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Citation: Ruoyu Cao, Jiaxin Chen, Jiaen Hu, Youting Zhai, Jiacong Fu, Lifen Hou, Xuebin Yan, Yanyang Li, Kai Li, Shuangquan Zang. Interactive Digital Experiment for Organic Synthesis: Designing Process and Case Presentation[J]. University Chemistry, ;2026, 41(1): 406-412. doi: 10.12461/PKU.DXHX202504022 shu

Interactive Digital Experiment for Organic Synthesis: Designing Process and Case Presentation

College of Chemistry, Zhengzhou University, Zhengzhou 450001, China

Corresponding author: Yanyang Li, Kai Li,
Received Date: 8 April 2025
Revised Date: 23 July 2025

In this work, we developed an interactive digital teaching model for experimental chemistry education. The approach employs digital technologies to perform retrosynthetic analysis of target compounds while evaluating different synthetic routes based on cost, safety, and yield parameters to identify optimal pathways for teaching purposes. Each route is systematically optimized to address potential operational challenges, with multiple troubleshooting solutions incorporated. The final output is presented as an interactive video-based digital experiment. Within this framework, instructors can utilize digital tools to design experimental pathways and generate randomized events, thereby guiding students through problem identification, solution development, and experimental completion. This interactive teaching paradigm represents a significant advancement over traditional linear virtual experiments, offering enhanced flexibility, personalization, real-time feedback, and improved differentiation capabilities. The methodology demonstrates considerable potential for broader application in experimental chemistry education.
- Interactive,
- Digitization,
- Organic synthesis,
- Interactive video
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