用科学打败牙菌斑的“膜法”

引用本文: 郑直, 马琪, 刘飞扬, 陈谷奎, 赵军龙. 用科学打败牙菌斑的“膜法”[J]. 大学化学, 2026, 41(2): 295-300. doi: 10.12461/PKU.DXHX202502088 shu

Citation: Zhi Zheng, Qi Ma, Feiyang Liu, Gukui Chen, Junlong Zhao. Defeating Dental Plaque with Science: Unlocking the Power of Biofilm Management[J]. University Chemistry, 2026, 41(2): 295-300. doi: 10.12461/PKU.DXHX202502088 shu

用科学打败牙菌斑的“膜法”

郑直 ^1, ,
马琪 ^2, ,
刘飞扬 ^1, ,
陈谷奎 ^{2,
,} ,
赵军龙 ^{2,
,}

1.
西北大学化学与材料科学学院, 化学国家级实验教学示范中心(西北大学), 西安 710127;
2.
西北大学医学院, 西安 710069

通讯作者: 陈谷奎,E-mail:zhaojunlong327@163.com; 赵军龙,E-mail:gukuichen@nwu.edu.cn

基金项目:
西安市社科规划项目(25JY135)

摘要: 牙菌斑是多种口腔致病菌通过胞外聚合物黏附形成的复合体，具有不易察觉、不易根除、危害性大等特点，是引发牙周疾病的关键因素。本文通过叙述手法，展示了牙菌斑的检测、治疗和预防策略，旨在向大众普及口腔卫生知识、纠正牙齿保健的错误认知。希望通过本文的介绍，能引导大众正确认识以牙菌斑为代表的细菌生物被膜，了解其在生产生活中的积极作用，感受科技“化腐朽为神奇”的魅力。

关键词:

English

Defeating Dental Plaque with Science: Unlocking the Power of Biofilm Management

Zhi Zheng ^1, ,
Qi Ma ^2, ,
Feiyang Liu ^1, ,
Gukui Chen ^{2,
,} ,
Junlong Zhao ^{2,
,}

1.
National Chemistry Experimental Teaching Demonstration Center, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China;
2.
School of Medicine, Northwest University, Xi'an 710069, China

Corresponding author: Gukui Chen, ; Junlong Zhao,

Received Date: 17 February 2025
Revised Date: 24 February 2025
Available Online: 18 September 2025

Abstract: Dental plaque, a complex biofilm formed by various oral pathogens embedded in an extracellular polymeric substance (EPS) matrix, is characterized by its inconspicuous nature, strong adherence, and resistance to removal, making it a key factor in the development of periodontal diseases. This article employs a narrative approach to present strategies for the detection, treatment, and prevention of dental plaque, aiming to enhance public awareness of oral hygiene and correct misconceptions about dental care. Furthermore, it seeks to foster a deeper understanding of bacterial biofilms, exemplified by dental plaque, highlighting their positive roles in various aspects of life and showcasing the transformative power of science in turning challenges into opportunities.

Key words:

Dental plaque
/ EPS
/ Oral hygiene
/ Biofilms

1. [1]
  乌日汉, 郭小娟, 王怡, 王金锋, 赵方庆. 微生物学报, 2018, 58 (11), 1950.
2. [2]
  郑欣, 程磊, 周学东. 中华口腔医学杂志, 2024, 59 (1), 14.
3. [3]
  Fasoulas, A.; Pavlidou, E.; Petridis, D.; Mantzorou, M.; Seroglou, K.; Giaginis, C. Heliyon 2019, 5 (7), e02064.Fasoulas, A.; Pavlidou, E.; Petridis, D.; Mantzorou, M.; Seroglou, K.; Giaginis, C. Heliyon 2019, 5 (7), e02064.
4. [4]
  肖澜. 牙结石的生物矿化及抑制研究[硕士学位论文]. 武汉: 武汉理工大学, 2022.
5. [5]
  Koo, H.; Allan, R. N.; Howlin, R. P.; Stoodley, P.; Hall-Stoodley, L. Nat. Rev. Microbiol. 2017, 15 (12), 740.Koo, H.; Allan, R. N.; Howlin, R. P.; Stoodley, P.; Hall-Stoodley, L. Nat. Rev. Microbiol. 2017, 15 (12), 740.
6. [6]
  Moszner, N.; Salz, U. Prog. Polym. Sci. 2001, 26 (4), 535.Moszner, N.; Salz, U. Prog. Polym. Sci. 2001, 26 (4), 535.
7. [7]
  麦穗, 韦曦, 凌均棨. 中华口腔医学杂志, 2021, 56 (1), 51.
8. [8]
  Leroy, N.; Bres, E. Eur. Cells Mater. 2001, No. 2, 36.Leroy, N.; Bres, E. Eur. Cells Mater. 2001, No. 2, 36.
9. [9]
  甄雪燕. 中国卫生人才, 2021, No. 4, 74.
10. [10]
  樊明文, 周学东. 牙体牙髓病学. 北京: 人民卫生出版社, 2008.
11. [11]
  Philipp, L. A.; Bühler, K.; Ulber, R.; Gescher, J. Nat. Rev. Microbiol. 2024, 22 (5), 276.Philipp, L. A.; Bühler, K.; Ulber, R.; Gescher, J. Nat. Rev. Microbiol. 2024, 22 (5), 276.

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

用科学打败牙菌斑的“膜法”

通讯作者: 陈谷奎,E-mail:zhaojunlong327@163.com; 赵军龙,E-mail:gukuichen@nwu.edu.cn

English

Defeating Dental Plaque with Science: Unlocking the Power of Biofilm Management

Corresponding author: Gukui Chen, ; Junlong Zhao,

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

用科学打败牙菌斑的“膜法”

通讯作者: 陈谷奎,E-mail:zhaojunlong327@163.com; 赵军龙,E-mail:gukuichen@nwu.edu.cn

English

Defeating Dental Plaque with Science: Unlocking the Power of Biofilm Management

Corresponding author: Gukui Chen, ; Junlong Zhao,

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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通讯作者: 陈斌, bchen63@163.com

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