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Citation: Gengjia Chen, Junjie Ou. Application of the van Deemter Equation in Instrumental Analysis Teaching: A Case of Organic Polymer Monolithic Columns[J]. University Chemistry, ;2025, 40(11): 362-368. doi: 10.12461/PKU.DXHX202502003 shu

Application of the van Deemter Equation in Instrumental Analysis Teaching: A Case of Organic Polymer Monolithic Columns

Gengjia Chen ,
Junjie Ou ^,

College of Chemistry and Materials Science, Northwest University, Xi'an 710127, China

Corresponding author: Junjie Ou, junjieou@nwu.edu.cn
Received Date: 8 February 2025
Revised Date: 18 April 2025

High-performance liquid chromatography (HPLC) occupies a pivotal position in the field of instrumental analysis. Nevertheless, current university courses in instrumental analysis often lack in-depth exploration of the intricate structure of stationary phases and the critical variables in the van Deemter equation that influence separation efficiency. This paper examines organic polymer monolithic columns prepared through traditional free radical polymerization and click polymerization methods, analyzing how their structure and morphology affect the A, B, and C terms of the van Deemter equation. The aim is to enhance students' understanding of the fundamental principles underlying the van Deemter equation.
- Monolithic column,
- Instrumental analysis,
- High-performance liquid chromatography,
- van Deemer equation
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