Citation:
Ying Zhang, Fang Ge, Zhimin Luo. AI-Driven Biochemical Teaching Research: Predicting the Functional Effects of Gene Mutations[J]. University Chemistry,
;2025, 40(3): 277-284.
doi:
10.12461/PKU.DXHX202412104
-
Guided by the principle of “integrating science and education, collaboratively cultivating talent”, this paper explores the integration of Artificial Intelligence (AI) with biochemistry teaching and research. It examines the application of AI technology in the reform of biochemistry education, specifically through the development of a case study in biomedical engineering that predicts the functional effects of gene mutations using AI. The paper discusses the design and implementation of this AI-driven teaching case, focusing on the case’s background, curriculum design, teaching strategies, and evaluation of its impact. This approach aims to cultivate interdisciplinary thinking in students, enhancing their ability to integrate knowledge across fields.
-
-
-
[1]
-
[2]
-
[3]
-
[4]
-
[5]
-
[6]
-
[7]
-
[8]
Stankovic, S.; Shekari, S.; Huang, Q. Q.; Gardner, E. J.; Ivarsdottir, E. V.; Owens, N. D. L.; Mavaddat, N.; Azad, A.; Hawkes, G.; Kentistou, K. A.; et al. Nature 2024, 633, 608.
-
[9]
Aboelkassem, Y. Biophys. J. 2024, 123 (3), 124a.
-
[10]
-
[11]
AlphaMissense. [2025-02-25]. https://github.com/deepmind/alphamissense
-
[12]
DeepSequence. [2025-02-25]. https://github.com/debbiemarkslab/DeepSequence
-
[13]
Ensembl VEP. [2025-02-25]. https://www.ensembl.org/vep
-
[14]
dbNSFP. [2025-02-25]. http://database.liulab.science/dbNSFP
-
[1]
-
-
-
[1]
Cheng-an Tao , Jian Huang , Yujiao Li . Exploring the Application of Artificial Intelligence in University Chemistry Laboratory Instruction. University Chemistry, 2025, 40(9): 5-10. doi: 10.12461/PKU.DXHX202408132
-
[2]
Xiao Ma , Junjie Wang , Xin Chen , Jingcheng Li , Lihong Zhao , Xueping Sun , Shaojuan Cheng , Fang Wang . Exploring Innovative Approaches to Chemistry Instructional Organization Driven by Artificial Intelligence. University Chemistry, 2025, 40(9): 99-106. doi: 10.12461/PKU.DXHX202410085
-
[3]
Wuyi Feng , Di Zhao . Significance and Measures of Integrating Artificial Intelligence Technology into College Chemistry Teaching. University Chemistry, 2025, 40(9): 156-163. doi: 10.12461/PKU.DXHX202502107
-
[4]
Lingli Wu , Shengbin Lei . Generative AI-Driven Innovative Chemistry Teaching: Current Status and Future Prospects. University Chemistry, 2025, 40(9): 206-219. doi: 10.12461/PKU.DXHX202503069
-
[5]
Run Yang , Huajie Pang , Huiping Zang , Ruizhong Zhang , Zhicheng Zhang , Xiyan Li , Libing Zhang . Artificial Intelligence-Enabled DNA Computing: Exploring New Frontiers in Bioinformatics. University Chemistry, 2025, 40(9): 107-117. doi: 10.12461/PKU.DXHX202412135
-
[6]
Meirong Cui , Mo Xie , Jie Chao . Design and Reflections on the Integration of Artificial Intelligence in Physical Chemistry Laboratory Courses. University Chemistry, 2025, 40(5): 291-300. doi: 10.12461/PKU.DXHX202412015
-
[7]
Yan Zhang , Limin Zhou , Xiaoyan Cao , Mutai Bao . Exploring the Application of Artificial Intelligence in Marine-Themed Integrated Physical Chemistry Experiments. University Chemistry, 2025, 40(9): 118-125. doi: 10.12461/PKU.DXHX202503062
-
[8]
Huixin Dong , Zhenlei Zhou , Wenxin Zou , Juan Jin , Xiguang Liu , Yuzhong Niu , Lili Zhu , Hua Jiang . Exploration and Practice of Ideological and Political Education in Inorganic Chemistry Courses with the Assistance of Artificial Intelligence. University Chemistry, 2026, 41(3): 254-261. doi: 10.12461/PKU.DXHX202505003
-
[9]
Weigang Zhu , Jianfeng Wang , Qiang Qi , Jing Li , Zhicheng Zhang , Xi Yu . Curriculum Development for Cheminformatics and AI-Driven Chemistry Theory toward an Intelligent Era. University Chemistry, 2025, 40(9): 34-42. doi: 10.12461/PKU.DXHX202412002
-
[10]
Ping Li , Chao Yin . Teaching Exploration and Practical Innovation of General Education Courses in the Context of Artificial Intelligence. University Chemistry, 2024, 39(10): 402-407. doi: 10.12461/PKU.DXHX202403075
-
[11]
Yifan Liu , Haonan Peng . AI-Assisted New Era in Chemistry: A Review of the Application and Development of Artificial Intelligence in Chemistry. University Chemistry, 2025, 40(7): 189-199. doi: 10.12461/PKU.DXHX202405182
-
[12]
Jizhu Zhou , Xiao Wei , Kaixue Wang . Deep Integration of Artificial Intelligence and Chemical Research: Applying the Fourth Paradigm and Evolving the Role of Chemists. University Chemistry, 2025, 40(12): 119-125. doi: 10.12461/PKU.DXHX202509003
-
[13]
Qifeng Zheng , Aimei Gao , Ruirui Zhao . Exploring a New Undergraduate Training Model for Chemistry Majors through “Science-Education-Innovation Integration” in the AI Era. University Chemistry, 2026, 41(2): 161-167. doi: 10.12461/PKU.DXHX202502056
-
[14]
Xiaoxuan Yu , Wukun Liu . Practice of Ideological and Political Education in Medicinal Chemistry for Pharmacy Administration Major: A Case Study on the Discovery of Cisplatin’s Anticancer Function. University Chemistry, 2025, 40(4): 408-414. doi: 10.12461/PKU.DXHX202405200
-
[15]
Fuxian Wan , Ying Li , Yuanhong Zhang , Shuhua Zhu , Jing Xu , Yanfang Wang , Lili Zhang . Exploration and Practice of Teaching in Agricultural Characteristic Organic Chemistry Course. University Chemistry, 2024, 39(2): 298-306. doi: 10.3866/PKU.DXHX202308041
-
[16]
Liangjun Chen , Yu Zhang , Zhicheng Zhang , Yongwu Peng . AI-Empowering Reform in University Chemistry Education: Practical Exploration of Cultivating Informationization and Intelligent Literacy. University Chemistry, 2025, 40(9): 220-227. doi: 10.12461/PKU.DXHX202503124
-
[17]
Yihui Song , Shangshang Qin , Kai Wu , Chengyun Jin , Bin Yu . 生物化学在高水平创新型药学人才培养中的交叉融合应用——以去甲基化酶LSD1抑制剂的活性评价为例. University Chemistry, 2025, 40(6): 341-352. doi: 10.12461/PKU.DXHX202406018
-
[18]
Xue Zhao , Guoyu Jiang , Haixia Wu . Teaching Practice and Reform of Analytical Chemistry for Non-Chemistry Majors. University Chemistry, 2026, 41(2): 123-130. doi: 10.12461/PKU.DXHX202503083
-
[19]
Xinghai Liu , Hongke Wu . Exploration and Practice of Ideological and Political Education in Heterocyclic Chemistry Based on "Fentanyl" Event. University Chemistry, 2024, 39(8): 359-364. doi: 10.3866/PKU.DXHX202312100
-
[20]
Lijun Zhou , Dongmei Wang , Jiameng Wang , Tongjie Yao , Mei Qi , Yin Kong , Yan Song . Teaching Case Design of “Degradation and Aging” as an Ideological and Political Demonstration Course. University Chemistry, 2025, 40(4): 80-86. doi: 10.12461/PKU.DXHX202405113
-
[1]
Metrics
- PDF Downloads(0)
- Abstract views(1583)
- HTML views(282)
Login In
DownLoad: