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Citation: Meihong Luo, Hongyu Wang. Teaching Reform of Benzoin Oxidation Experiment in the Context of Green Pharmaceutical Chemistry[J]. University Chemistry, ;2025, 40(5): 376-382. doi: 10.12461/PKU.DXHX202411055 shu

Teaching Reform of Benzoin Oxidation Experiment in the Context of Green Pharmaceutical Chemistry

Meihong Luo ,
Hongyu Wang ^,

School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, Shandong Province, China

Corresponding author: Hongyu Wang, why@ouc.edu.cn
Received Date: 19 November 2024
Revised Date: 23 January 2025

Green chemistry has emerged as a pivotal focus in organic synthesis and pharmaceutical development. This paper introduces a photocatalytic benzoin oxidation experiment grounded in green chemistry principles. The experiment utilizes oxygen from the air as the oxidant, 9-mesityl-10-methylacridinium perchlorate as the photocatalyst, triethylenediamine as the base, and chloroform as the solvent, subjected to irradiation by a 456 nm LED for 2 h. By optimizing the experimental conditions, we established the optimal reaction parameters, which were subsequently implemented in undergraduate laboratory courses, thereby integrating scientific research with education.
- Green organic chemistry,
- Photocatalysis,
- Benzoin oxidation,
- Undergraduate teaching experiment
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