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Citation: Xudong Liu, Huili Fan, Junping Xiao, Min Yang, Yan Li. Teaching Approaches to the A_E + A_N Mechanism of Electrophilic Addition Reactions between Olefins and Inorganic Acids in Organic Chemistry[J]. University Chemistry, ;2025, 40(7): 367-372. doi: 10.12461/PKU.DXHX202409041 shu

Teaching Approaches to the A_E + A_N Mechanism of Electrophilic Addition Reactions between Olefins and Inorganic Acids in Organic Chemistry

School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China

Corresponding author: Yan Li, liyan310@ustb.edu.cn
Received Date: 6 September 2024
Revised Date: 23 October 2024

Electrophilic addition reactions between olefins and inorganic acids are a key topic in university-level organic chemistry courses. This paper addresses the challenge of predicting the products of these reactions, which often proves difficult. By employing both static and dynamic analyses, in combination with nuclear magnetic resonance (NMR) carbon spectra and resonance theory, we provide a comprehensive analysis of the underlying mechanisms. Additionally, we propose a simplified method for predicting the major and minor products of electrophilic addition based on regioselectivity. This approach effectively helps senior undergraduates and graduate students overcome challenges in product prediction.
- Electrophilic addition,
- Nuclear magnetic resonance,
- Resonance theory,
- Electronic effect
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Teaching Approaches to the AE + AN Mechanism of Electrophilic Addition Reactions between Olefins and Inorganic Acids in Organic Chemistry

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通讯作者: 陈斌, bchen63@163.com

Teaching Approaches to the A_E + A_N Mechanism of Electrophilic Addition Reactions between Olefins and Inorganic Acids in Organic Chemistry