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Citation: Yihui Song, Shangshang Qin, Kai Wu, Chengyun Jin, Bin Yu. 生物化学在高水平创新型药学人才培养中的交叉融合应用——以去甲基化酶LSD1抑制剂的活性评价为例[J]. University Chemistry, ;2025, 40(6): 341-352. doi: 10.12461/PKU.DXHX202406018 shu

生物化学在高水平创新型药学人才培养中的交叉融合应用——以去甲基化酶LSD1抑制剂的活性评价为例

1.
School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China;
2.
State Key Laboratory of Antiviral Drugs, Pingyuan Laboratory, College of Chemistry, Zhengzhou University, Zhengzhou 450001, China

Received Date: 11 June 2024
Revised Date: 14 August 2024

药学是一门综合性学科，涉及生物学、化学、医学等多个领域。作为连接生物学和化学的桥梁，生物化学是药学教育中的一门基础必修课程，对于培养高水平创新型药学人才具有重要意义。但生物化学各章节相对独立，理论知识点繁多且零散，学生理解学习和灵活应用难度较大。如何有效地将生物化学基础理论知识与药学实践交叉应用，培养出具有创新能力和实践技能的药学人才是当前药学教育教学改革的重要课题。本文以去甲基化酶LSD1抑制剂的活性评价为例，采用传统理论教学与案例教学相结合的教学模式有机地将生物化学的理论知识与药物研发过程系统联系起来，激发学生的学习兴趣，培养学生的科研创新精神。本文旨在探讨闭环式案例教学模式在生物化学与药学教育中的融合应用，培养学生的分析思维能力和问题解决能力，引导他们运用生物化学知识分析和解决药物研发中的实际问题，以期为我国高水平创新型药学人才培养提供参考和借鉴。
- Biochemistry,
- Pharmaceutical talent training,
- Closed-loop case-based education,
- Integrated application,
- Research innovation
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