Citation: SHANG Jizhen, LI Zhi, XI Dongmei, ZHANG Shusheng. Progress in Biological Nanopore-based Analysis Technology[J]. Chinese Journal of Applied Chemistry, ;2017, 34(8): 855-867. doi: 10.11944/j.issn.1000-0518.2017.08.170103 shu

Progress in Biological Nanopore-based Analysis Technology

SHANG Jizhen ^a,b ,
LI Zhi ^b ,
XI Dongmei ^b,, ,
ZHANG Shusheng ^b,,

a.
The Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, Shandong 273165, China
b.
Shandong Provincial Key Laboratory of Detection Technology for Tumor Makers, College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shangdong 276005, China

Corresponding author: XI Dongmei, dongmxi@126.com ZHANG Shusheng, shushzhang@126.com
Received Date: 5 April 2017
Revised Date: 17 May 2017
Accepted Date: 22 May 2017

Fund Project: Supported by the National Natural Science Foundation of China(No.21405073, No.21535002)the National Natural Science Foundation of China No.21405073the National Natural Science Foundation of China No.21535002

Figures(15)

Biological nanopore sensing has been developed as an attractive single-molecule tool with advantages of being rapid, low-cost, and label-free. Nanopores are not only being widely developed for DNA sequencing, but they also have been utilized to analyze a wide range of analytes at the single-molecule level. This review summarizes and prospects the principle of the nanopore analysis and nanpore category, with an emphasis on the progress in nanopore-based DNA sequencing and single-molecule analysis.
- biological nanopore,
- DNA sequencing,
- single-molecule analysis
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