Citation: XIE Lefang, XING Rui, WANG Fang, WANG Li. Antibacterial Activities of Six Kinds of Polyoxometalates[J]. Chinese Journal of Applied Chemistry, ;2017, 34(6): 700-704. doi: 10.11944/j.issn.1000-0518.2017.06.160370 shu

Antibacterial Activities of Six Kinds of Polyoxometalates

  • Corresponding author: WANG Li, wanglimerry@jmu.edu.cn
  • Received Date: 18 September 2016
    Revised Date: 17 October 2016
    Accepted Date: 5 December 2016

    Fund Project: 20871054 the National Natural Science Foundation of China2137107 the National Natural Science Foundation of China

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  • In this study, we synthesised five kinds of Keggin-type transition metal substituted polyoxometalates(Na7PMo11M(Ⅱ)O40(M=Mn, Fe, Zn, Co, Ni), abbreviated as PMo11M(Ⅱ)(M=Mn, Fe, Zn, Co, Ni)). The structures of these compounds were characterized by UV-visible absorption spectrum and Fourier transform infrared spectrometer(FTIR). And then the antibacterial activities of the five kinds of Keggin-type transition metal substituted polyoxometalates(PMo11M(Ⅱ)(M=Mn, Fe, Zn, Co, Ni) and their parent H3PMo12O40(abbreviated PMo12) on Sarcina lutea(S.lutea), Staphylococcus aureus(S.aureus), Bacillus subtilis(B.subtilis) and Escherichia coli(E.coli) were investigated by Oxford plate. Also, the minimum inhibitory concentration(MIC) and the minimum bactericidal concentration(MBC) were tested by broth microdilution methods. The results show that the six kinds of polyoxometalates can inhibit the proliferation of these four different kinds of bacteria to different extents, and the antimicrobial activities of all compounds on S.lutea and S.aureus are more effective than those against B.Subtilis and E.coli. Among these compounds, the antibacterial activities of (PMo11M(Ⅱ)(M=Ni, Mn, Zn)) were superior to the other three compounds. This study will provide more theoretical and experimental supports for polyoxometalates as preservative agents in fruit and vegetables.
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