碰撞气体的种类和压力对离子阱质谱性能的影响

引用本文: 徐福兴, 党乾坤, 丁航宇, 黄正旭, 汪源源, 周振, 丁传凡. 碰撞气体的种类和压力对离子阱质谱性能的影响[J]. 分析化学, 2017, 45(4): 587-592. doi: 10.11895/j.issn.0253-3820.160826 shu

Citation: XU Fu-Xing, DANG Qian-Kun, DING Hang-Yu, HUANG Zheng-Xu, WANG Yuan-Yuan, ZHOU Zhen, DING Chuan-Fan. Performance Investigation of Ion Trap with Various Collision gas and Pressures[J]. Chinese Journal of Analytical Chemistry, 2017, 45(4): 587-592. doi: 10.11895/j.issn.0253-3820.160826 shu

碰撞气体的种类和压力对离子阱质谱性能的影响

1.
复旦大学电子工程系, 上海 200433;
2.
复旦大学化学系激光化学研究所, 上海 200433;
3.
广州禾信仪器股份有限公司, 广州 510530
基金项目:
本文系科技部十二五重大科学仪器设备开发专项（No.2011YQ14015006）资助

摘要: 基于数字离子阱技术，研究了离子阱质谱分析实验过程使用的碰撞气体种类及压力对离子阱质谱性能，如质量分辨能力、信号强度、串级质谱分析，以及低质量截止效应等的影响。实验过程中，在离子的激发和碰撞诱导解离阶段，分别采用质量数不等的氦气（质量数=4 amu）、氮气（质量数=28 amu）、氩气（质量数=40 amu）等作为碰撞气体，以及不同的气体压力，研究了它们对质谱性能的影响。结果表明，当采用质量数较大的氩气作为碰撞气体时，可以有效改善低质量数截止效应和提高离子碰撞过程中的能量转移效率，同时提高离子捕获和解离效率，但是质量分辨率会明显降低。在获得较高质量分辨率方面，氦气作为碰撞气体时效果最好。在气压相同的情况下，质量数大的碰撞气体有利于提高串级质谱分析效率，即获得更多碎片离子峰和更多有关母体离子结构的信息。

关键词:

English

Performance Investigation of Ion Trap with Various Collision gas and Pressures

1.
Department of Electronic Engineering, Fudan University, Shanghai 200433, China;
2.
Department of Chemistry and Laser Chemistry Institute, Fudan University, Shanghai 200433, China;
3.
Guangzhou Hexin Instrument Co.Ltd, Guangzhou 510530, China
Received Date: 11 November 2016
Revised Date: 12 January 2017
Fund Project:
This work was supported by the National Ministry of Science and Technology of China (No. 2011YQ14015006)

Abstract: Ion trap performances are investigated based on digital ion trap technique with different collision gases at different pressures. Collision gases of helium (4 amu), nitrogen (28 amu) and argon (40 amu) with various pressures are adopted in ion excitation and dissociation stages to investigate the ion trap performances, including mass resolution, signal intensity, tandem mass spectrometric analysis ability and low-mass cut off (LMCO) effect. It is found that when heavy gas of argon is used, energy can be efficiently transferred and LMCO effect is decreased with higher ion capture and dissociation efficiencies but with low mass resolution. Higher mass resolution is realized with helium as collision gas. Furthermore, at the same gas pressure, heavy gas is beneficial to abundant fragment ions and structural information of precursor ion.

Key words:

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沈阳化工大学材料科学与工程学院沈阳 110142

碰撞气体的种类和压力对离子阱质谱性能的影响

English

Performance Investigation of Ion Trap with Various Collision gas and Pressures

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中国化学会秘书处

碰撞气体的种类和压力对离子阱质谱性能的影响

English

Performance Investigation of Ion Trap with Various Collision gas and Pressures

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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