红霉素分子印迹二维光子晶体水凝胶传感器的研究

引用本文: 高敏君, 刘根起, 薛亚峰, 陈小娟, 师维江, 范晓东. 红霉素分子印迹二维光子晶体水凝胶传感器的研究[J]. 分析化学, 2017, 45(5): 727-733. doi: 10.11895/j.issn.0253-3820.160771 shu

Citation: GAO Min-Jun, LIU Gen-Qi, XUE Ya-Feng, CHEN Xiao-Juan, SHI Wei-Jiang, FAN Xiao-Dong. Erythromycin Molecularly Imprinted Two-dimensional Photonic Crystal Hydrogel Sensor[J]. Chinese Journal of Analytical Chemistry, 2017, 45(5): 727-733. doi: 10.11895/j.issn.0253-3820.160771 shu

红霉素分子印迹二维光子晶体水凝胶传感器的研究

西北工业大学理学院应用化学系, 陕西省高分子科学与技术重点实验室, 西安 710129
基金项目:
本文系西北工业大学研究生创意创新种子基金（No. Z2016168）资助

摘要: 以红霉素为印迹分子，聚苯乙烯二维光子晶体为模板，甲基丙烯酸为功能单体，乙二醇二甲基丙烯酸甲酯为交联剂，2，2-二乙氧基苯乙酮为引发剂，紫外光引发聚合，在甲醇-乙酸（9∶1，V/V）中洗脱印迹分子，得到能够特异性识别红霉素的分子印迹二维光子晶体水凝胶。通过测试德拜环直径变化，研究了此水凝胶在红霉素溶液中的响应性能。实验结果表明，当红霉素的浓度从0增加到1×10^-6 mol/L时，德拜环直径增加6 mm，相应的晶格间距减小30 nm。此外，水凝胶在1×10^-6 mol/L红霉素的类似物罗红霉素、琥乙红霉素溶液中，德拜环直径仅分别增加1.5和2.0 mm，表明此光子晶体水凝胶具有良好的选择性，有望用于红霉素低成本的简易检测。

关键词:

English

Erythromycin Molecularly Imprinted Two-dimensional Photonic Crystal Hydrogel Sensor

Shaanxi Key Laboratory of Macromolecular Science and Technology, Department of Applied Chemistry, School of Science, Northwestern Polytechnical University, Xi'an 710129, China
Received Date: 19 October 2016
Revised Date: 04 February 2017

Abstract: A molecularly imprinted two-dimensional photonic crystal hydrogel sensor was developed with erythromycin as imprinted molecule, polystyrene two-dimensional photonic crystal as templates, methanol as solvent, methacrylic acid as monomers and ethylene glycol dimethylacrylate as cross-linkers. The imprinted molecule was removed by methanol/acetic acid (9∶1, V/V). The results showed that the diameter of Debye ring increased 6 mm when the concentration of EM changed from 0 to 1×10^-6 mol/L. Namely the lattice spacing decreased 30 nm. In addition, the diameter of Debye ring only increased 1.5 and 2.0 mm when the hydrogel immersed in 1×10^-6 mol/L roxithromycin (RM) or erythromycin ethylsuccinate (EEs) solution. The result indicated that the sensor had high selectivity and could be used in determination of erythromycin with low cost and easy operation.

Key words:

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沈阳化工大学材料科学与工程学院沈阳 110142

红霉素分子印迹二维光子晶体水凝胶传感器的研究

English

Erythromycin Molecularly Imprinted Two-dimensional Photonic Crystal Hydrogel Sensor

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

红霉素分子印迹二维光子晶体水凝胶传感器的研究

English

Erythromycin Molecularly Imprinted Two-dimensional Photonic Crystal Hydrogel Sensor

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

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CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

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CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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