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Citation: Shunping WANG, Chuandong GE, Shuguang QU, Tianduo LI, Shaomin WANG, Qingyuan YANG. Synthesis of a fluorescent probe based on urea-based coordination and Si—O bond cleavage for F- and Cr(Ⅵ) detection[J]. Chinese Journal of Inorganic Chemistry, ;2026, 42(2): 297-308. doi: 10.11862/CJIC.20250214 shu

Synthesis of a fluorescent probe based on urea-based coordination and Si—O bond cleavage for F- and Cr(Ⅵ) detection

  • 1.

    School of Chemical Engineering and Technology, Xi′an Jiaotong University, Xi′an 710049, China

  • 2.

    Qihe Lihou Chemical Industry Co., Ltd., Dezhou, Shandong 251100, China

  • 3.

    School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China

Figures(11)

  • A novel bifunctional fluorescent probe 1-methyl-2, 4-bis[2-(tert-butyldimethylsilyloxy)ethylurea]benzene (T1) based on urea-based coordination and Si—O bond cleavage was designed and synthesized for highly selective detection of Cr(Ⅵ) and F- in environmental and biological samples. The probe exhibited excellent recognition performance in dimethyl sulfoxide/water (DMSO/H2O, 1∶1, V/V) solvent. For Cr(Ⅵ) detection, T1 showed fluorescence quenching at 395 nm based on urea coordination with a detection limit of 4.70×10-7 mol·L-1, without interference from other metal ions. For F- recognition, the probe displayed significant fluorescence enhancement at 320 nm via Si—O bond cleavage mechanism with a detection limit of 7.07×10-8 mol·L-1, maintaining high selectivity in the presence of various anions. Spectroscopic analyses confirmed that T1 binds Cr(Ⅵ) in a 1∶2 stoichiometric ratio (Ka=2.62×104 L·mol-1) and reacts quantitatively with F- through Si—O bond cleavage in a molar ratio of 1∶2. The probe showed good linear response in the 0-20.00 μmol·L-1 range, providing an efficient analytical tool for environmental monitoring and biomedical detection.
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