Citation: Ji-Qiu YIN, Yong-Lin AN, Xian-Chao JIA, Yang JIAO. Recognition and Cell Imaging of Zn²⁺ by Coumarin Derivative Fluorescence Sensor[J]. Chinese Journal of Inorganic Chemistry, ;2022, 38(2): 368-376. doi: 10.11862/CJIC.2022.039 shu

Recognition and Cell Imaging of Zn²⁺ by Coumarin Derivative Fluorescence Sensor

Ji-Qiu YIN ^{1, 2} ,
Yong-Lin AN ¹ ,
Xian-Chao JIA ¹ ,
Yang JIAO ^1,,

1.
State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian, Liaoning 116024, China
2.
College of Medical Laboratory, Dalian Medical University, Dalian, Liaoning 116044, China

Corresponding author: Yang JIAO, jiaoyang@dlut.edu.cn
Received Date: 30 July 2021
Revised Date: 17 November 2021

Figures(7)

Coumarin-derived fluorescence sensor was designed and synthesized to selectively recognize Zn²⁺ ions. The structure and fluorescence properties of the sensor were investigated by NMR, MS, fluorescence spectroscopy, and other technical methods. Sensor CANQ exhibited conspicuous fluorescent enhancement response to Zn²⁺ ion and had the characteristic of fast response, high selectivity, and good biocompatibility. It has been applied to the imaging of Zn²⁺ ions in MCF-7 cells.
- Zn²⁺ ion,
- coumarin derivative,
- fluorescent sensor,
- recognition
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Recognition and Cell Imaging of Zn2+ by Coumarin Derivative Fluorescence Sensor

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Recognition and Cell Imaging of Zn²⁺ by Coumarin Derivative Fluorescence Sensor