Citation: ZHONG Xin, HUANG Zi-Yang, ZHAO Meng-Yang. Preparation and Bioactivity Test in Vitro of HA/ZnO/SiO₂ Gradient Coating Materials[J]. Chinese Journal of Inorganic Chemistry, ;2020, 36(11): 2041-2047. doi: 10.11862/CJIC.2020.210 shu

Preparation and Bioactivity Test in Vitro of HA/ZnO/SiO₂ Gradient Coating Materials

College of Chemistry and Materials Science, Fujian Normal University, Fuzhou 350007, China

Corresponding author: HUANG Zi-Yang, zyhuang@fjnu.edu.cn
Received Date: 3 February 2020
Revised Date: 30 May 2020

Figures(12)

Hydroxyapatite (HA), chitosan (CS), ZnO and SiO₂ suspensions were distributed by zonal electrophoresis, and then HA/CS/ZnO/SiO₂ composite coating material on the Ti-based surface was obtained by electrophoretic deposition in a reverse electric field subsequently. An HA/ZnO/SiO₂ coating material (Z1) was fabricated by calcination at 710℃ for 2 h. At the same time, another HA/ZnO/SiO₂ coating material (E1) was directly prepared only by electrophoretic deposition for comparison. Both Si and Zn elements with a gradient distribution in the radial direction of the coating was found by X-ray energy spectrum analysis, which indicates that Z1 has certain gradient properties. Then, scanning electron microscope, powder X-ray diffraction and Fourier transform infrared spectroscopy were used to characterize the two coating materials. It was found that Z1 has more excellent properties than E1, mainly manifested in the bonding strength of Z1 and Ti substrate up to 31.2 MPa, and the degree of carbonated apatite on the surface of Z1 was more complete after 14 days of culture in HEPES simulated body fluid. In addition, the bacteriostatic effect test of Z1 showed that the bacteriostatic rates of Z1 powder against E. coli and S. aureus were up to 81.7% and 89.4%, respectively.
- hydroxyapatite/ZnO/SiO₂ gradient coating material,
- bonding strength,
- bacteriostatic property,
- in vitro bioactivity
1. [1]
  Shen X, Yang Z, McCool E N, et al. Trac-Trends Anal. Chem., 2019, 120:115644 doi: 10.1016/j.trac.2019.115644
2. [2]
  Sequeira D B, Seabra C M, Palma P J, et al. J. Funct. Biomater., 2018, 9(4):74 doi: 10.3390/jfb9040074
3. [3]
  Furko M, Jiang Y, Wilkins T, et al. Mater. Sci. Eng. C, 2016, 62:249-259 doi: 10.1016/j.msec.2016.01.060
4. [4]
  Golovanova O A, Zaits A Ⅴ. Inorg. Mater., 2018, 54(11):1124-1130 doi: 10.1134/S0020168518110067
5. [5]
  Sadat-Shojai M, Khorasani M T, Dinpanah-Khoshdargi E, et al. Acta Biomater., 2013, 9(8):7591-7621 doi: 10.1016/j.actbio.2013.04.012
6. [6]
  O'Hare P, Meenan B J, Burke G A, et al. Biomaterials, 2010, 31(3):515-522 doi: 10.1016/j.biomaterials.2009.09.067
7. [7]
  XU Fu-Qiu, CHEN Hua-Jun, DING Wu-Xiu. Chinese J. Inorg. Chem., 2013, 29(12):2582-2586
8. [8]
  Hendi A A. J. Alloys Compd., 2017, 712:147-151 doi: 10.1016/j.jallcom.2017.04.021
9. [9]
  Azari R, Rezaie H R, Khavandi A. Ceram. Int., 2019, 45(14):17545-17555 doi: 10.1016/j.ceramint.2019.05.317
10. [10]
  Zhao Y, Lu M, Fan Z, et al. J. Eur. Ceram. Soc., 2020, 40(3):798-810 doi: 10.1016/j.jeurceramsoc.2019.10.037
11. [11]
  WANG Yan-Ling, DING Hong, HE Wei, et al. Journal of Oral Science Research, 2019, 35(11):1070-1073
12. [12]
  Tayyaba Q, Shahzad M, Butt A Q, et al. Surf. Coat. Technol., 2019, 375:197-204 doi: 10.1016/j.surfcoat.2019.07.014
13. [13]
  Huey D J, Hu J C, Athanasiou K A. Science, 2012, 338(6109):917-921 doi: 10.1126/science.1222454
14. [14]
  Dzherayan T G, Vanifatova N G, Fadeeva Ⅰ Ⅴ, et al. J. Anal. Chem., 2015, 70(5):608-614 doi: 10.1134/S1061934815050032
15. [15]
  Dutta D. Electrophoresis, 2018, 39(5/6):760-769
16. [16]
  HUANG Zi-Yang, ZHANG Lan, LIANG Guang-Chao. Acta Chim. Sinica, 2012, 70(3):30-35
17. [17]
  Kim H, Camata R P, Chowdhury S, et al. Acta Biomater., 2010, 6(8):3234-3241 doi: 10.1016/j.actbio.2010.02.031
18. [18]
  Li G, Liang G, Zhao S, et al. Adv. Appl. Ceram., 2015, 114(3):164-174 doi: 10.1179/1743676114Y.0000000210
19. [19]
  Applerot G, Lipovsky A, Dror R, et al. Adv. Funct. Mater., 2009, 19(6):842-852 doi: 10.1002/adfm.200801081
20. [20]
  Ravichandran K, Snega S, Begum N J, et al. Superlattices Microstruct., 2014, 69:17-28 doi: 10.1016/j.spmi.2014.01.020
1. [1]
  Xinting XIONG , Zhiqiang XIONG , Panlei XIAO , Xuliang NIE , Xiuying SONG , Xiuguang YI . Synthesis, crystal structures, Hirshfeld surface analysis, and antifungal activity of two complexes Na(Ⅰ)/Cd(Ⅱ) assembled by 5-bromo-2-hydroxybenzoic acid ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1661-1670. doi: 10.11862/CJIC.20240145
2. [2]
  Lijuan Wang , Yuping Ning , Jian Li , Sha Luo , Xiongfei Luo , Ruiwen Wang . Enhancing the Advanced Nature of Natural Product Chemistry Laboratory Courses with New Research Findings: A Case Study of the Application of Berberine Hydrochloride in Photodynamic Antimicrobial Films. University Chemistry, 2024, 39(11): 241-250. doi: 10.12461/PKU.DXHX202403017
3. [3]
  Jia Zhou , Huaying Zhong . Experimental Design of Computational Materials Science Combined with Machine Learning. University Chemistry, 2025, 40(3): 171-177. doi: 10.12461/PKU.DXHX202406004
4. [4]
  Xin MA , Ya SUN , Na SUN , Qian KANG , Jiajia ZHANG , Ruitao ZHU , Xiaoli GAO . A Tb₂ complex based on polydentate Schiff base: Crystal structure, fluorescence properties, and biological activity. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1347-1356. doi: 10.11862/CJIC.20230357
5. [5]
  Jingke LIU , Jia CHEN , Yingchao HAN . Nano hydroxyapatite stable suspension system: Preparation and cobalt adsorption performance. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1763-1774. doi: 10.11862/CJIC.20240060
6. [6]
  Hong RAO , Yang HU , Yicong MA , Chunxin LÜ , Wei ZHONG , Lihua DU . Synthesis and in vitro anticancer activity of phenanthroline-functionalized nitrogen heterocyclic carbene homo- and heterobimetallic silver/gold complexes. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2429-2437. doi: 10.11862/CJIC.20240275
7. [7]
  Yu Wang , Haiyang Shi , Zihan Chen , Feng Chen , Ping Wang , Xuefei Wang . 具有富电子Pt^δ^-壳层的空心AgPt@Pt核壳催化剂：提升光催化H₂O₂生成选择性与活性. Acta Physico-Chimica Sinica, 2025, 41(7): 100081-. doi: 10.1016/j.actphy.2025.100081
8. [8]
  Haitang WANG , Yanni LING , Xiaqing MA , Yuxin CHEN , Rui ZHANG , Keyi WANG , Ying ZHANG , Wenmin WANG . Construction, crystal structures, and biological activities of two Ln^Ⅲ₃ complexes. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1474-1482. doi: 10.11862/CJIC.20240188
9. [9]
  Qiang Zhou , Pingping Zhu , Wei Shao , Wanqun Hu , Xuan Lei , Haiyang Yang . Innovative Experimental Teaching Design for 3D Printing High-Strength Hydrogel Experiments. University Chemistry, 2024, 39(6): 264-270. doi: 10.3866/PKU.DXHX202310064
10. [10]
  Hailian Tang , Siyuan Chen , Qiaoyun Liu , Guoyi Bai , Botao Qiao , Fei Liu . Stabilized Rh/hydroxyapatite Catalyst for Furfuryl Alcohol Hydrogenation: Application of Oxidative Strong Metal-Support Interactions in Reducing Conditions. Acta Physico-Chimica Sinica, 2025, 41(4): 100036-. doi: 10.3866/PKU.WHXB202408004
11. [11]
  Yifeng TAN , Ping CAO , Kai MA , Jingtong LI , Yuheng WANG . Synthesis of pentaerythritol tetra(2-ethylthylhexoate) catalyzed by h-MoO₃/SiO₂. Chinese Journal of Inorganic Chemistry, 2024, 40(11): 2155-2162. doi: 10.11862/CJIC.20240147
12. [12]
  Guang-Xu Duan , Queting Chen , Rui-Rui Shao , Hui-Huang Sun , Tong Yuan , Dong-Hao Zhang . Encapsulating lipase on the surface of magnetic ZIF-8 nanosphers with mesoporous SiO₂ nano-membrane for enhancing catalytic performance. Chinese Chemical Letters, 2025, 36(2): 109751-. doi: 10.1016/j.cclet.2024.109751
13. [13]
  Jin Yan , Chengxia Tong , Yajie Li , Yue Gu , Xuejian Qu , Shigang Wei , Wanchun Zhu , Yupeng Guo . Construction of a “Dual Support, Triple Integration” Chemical Safety Practical Education System. University Chemistry, 2024, 39(7): 69-75. doi: 10.12461/PKU.DXHX202405008
14. [14]
  Qiuting Zhang , Fan Wu , Jin Liu , Zian Lin . Chromatographic Stationary Phase and Chiral Separation Using Frame Materials. University Chemistry, 2025, 40(4): 291-298. doi: 10.12461/PKU.DXHX202405174
15. [15]
  Xiaohui Li , Ze Zhang , Jingyi Cui , Juanjuan Yin . Advanced Exploration and Practice of Teaching in the Experimental Course of Chemical Engineering Thermodynamics under the “High Order, Innovative, and Challenging” Framework. University Chemistry, 2024, 39(7): 368-376. doi: 10.3866/PKU.DXHX202311027
16. [16]
  . . Chinese Journal of Inorganic Chemistry, 2024, 40(12): 0-0.
17. [17]
  Ling Zhang , Jing Kang . Turn Waste into Valuable: Preparation of High-Strength Water-Based Adhesives from Polymethylmethacrylate Wastes: a Comprehensive Chemical Experiments. University Chemistry, 2024, 39(2): 221-226. doi: 10.3866/PKU.DXHX202306075
18. [18]
  Xinpin Pan , Yongjian Cui , Zhe Wang , Bowen Li , Hailong Wang , Jian Hao , Feng Li , Jing Li . Robust chemo-mechanical stability of additives-free SiO₂ anode realized by honeycomb nanolattice for high performance Li-ion batteries. Chinese Chemical Letters, 2024, 35(10): 109567-. doi: 10.1016/j.cclet.2024.109567
19. [19]
  Xiufang Wang , Donglin Zhao , Kehua Zhang , Xiaojie Song . “Preparation of Carbon Nanotube/SnS₂ Photoanode Materials”: A Comprehensive University Chemistry Experiment. University Chemistry, 2024, 39(4): 157-162. doi: 10.3866/PKU.DXHX202308025
20. [20]
  Rong Tian , Yadi Yang , Naihao Lu . Comprehensive Experimental Design of Undergraduate Students Based on Interdisciplinarity: Study on the Effect of Quercetin on Chlorination Activity of Myeloperoxidase. University Chemistry, 2024, 39(8): 247-254. doi: 10.3866/PKU.DXHX202312064

Get Citation

PDF

XML

Metrics

PDF Downloads(2)
Abstract views(756)
HTML views(103)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Preparation and Bioactivity Test in Vitro of HA/ZnO/SiO2 Gradient Coating Materials

Metrics

通讯作者: 陈斌, bchen63@163.com

Preparation and Bioactivity Test in Vitro of HA/ZnO/SiO₂ Gradient Coating Materials