Citation: TANG Guan-Xin, PENG Hong-Xia, HU Chuan-Yue, PENG Yang-Xi. Core-Spacer-Shell Structured Fe₃O₄@MoO₃@mSiO₂ Nanocarrier: Preparation and Controlled Release Drug[J]. Chinese Journal of Inorganic Chemistry, ;2018, 34(2): 337-345. doi: 10.11862/CJIC.2018.041 shu

Core-Spacer-Shell Structured Fe₃O₄@MoO₃@mSiO₂ Nanocarrier: Preparation and Controlled Release Drug

1.
Hunan Provincial Key Laboratory of Fine Ceramics and Powder Materials, School of Materials and Environmental Engineering, Hunan University of Humanities, Science and Technology, Loudi, Hunan 417000, China
2.
School of Materials Science and Engineering, Central South University, Changsha 410083, China

Corresponding author: PENG Hong-Xia, penghongxia1@126.com
Received Date: 10 August 2017
Revised Date: 2 November 2017

Figures(10)

MoO₃ interlayered Fe₃O₄@MoO₃@mSiO₂ core-spacer-shell structured drug nanocarrier was constructed to investigate loading and controllable release properties of ibuprofen (IBU). They possess high surface area of 222 cm²·g^-1, provide large accessible pore volume of 0.14 cm³·g^-1 for adsorption of drug molecules. At the same time they also have good magnetic responsiveness for drug targeting under foreigen magnetic under foreign magnetic fields, relatively good microwave heating conversion behavior for controlled release by microwave-triggered which is caused by MoO₃ interlayer. The IBU release of over 86% under microwave discontinuous irradiation within 360 min outclasses the only stirring release.
- Fe₃O₄@MoO₃@mSiO₂,
- magnetic,
- microwave heating conversion behavior,
- loading drug,
- controlled release
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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通讯作者: 陈斌, bchen63@163.com

Core-Spacer-Shell Structured Fe₃O₄@MoO₃@mSiO₂ Nanocarrier: Preparation and Controlled Release Drug