Citation: MAO Pan-Dong, HAN Xue-Feng, LI Shan-Shan, SHI Lin-Ying, WANG Yuan, WU Wei-Na. Syntheses, Crystal Structures and DNA-Binding Properties of Ni(Ⅱ)/Zn(Ⅱ)/Cd(Ⅱ)/Cu(Ⅱ) Complexes with 4-Methyl-1-((quinolin-8-yl) methylene)-thiosemicarbazide[J]. Chinese Journal of Inorganic Chemistry, ;2017, 33(4): 692-698. doi: 10.11862/CJIC.2017.067 shu

Syntheses, Crystal Structures and DNA-Binding Properties of Ni(Ⅱ)/Zn(Ⅱ)/Cd(Ⅱ)/Cu(Ⅱ) Complexes with 4-Methyl-1-((quinolin-8-yl) methylene)-thiosemicarbazide

MAO Pan-Dong ¹ ,
HAN Xue-Feng ^2,*,, ,
LI Shan-Shan ¹ ,
SHI Lin-Ying ¹ ,
WANG Yuan ¹ ,
WU Wei-Na ^1,*,,

1.
College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, Henan 454000, China
2.
Personnel Division, Henan Polytechnic University, Jiaozuo, Henan 454000, China

Corresponding author: HAN Xue-Feng, 108242720@qq.com WU Wei-Na, wuwn08@hpu.edu.cn
Received Date: 22 November 2016
Revised Date: 18 January 2017

Figures(4)

Four complexes[NiL₂]·2CH₃OH (1), [ZnL₂]·CH₃OH (2), [CdL₂]·CH₃CH₂OH (3) and[Cu₂L₂Cl₂] (4) (HL=4-methyl-1-((quinolin-8-yl) methylene)-thiosemicarbazide) have been synthesized and structurally determined by single-crystal X-ray diffraction. The results show that the structures of complexes 1~3 are quite similar. The metal ion in each complex with a distorted octahedron geometry is surrounded by two anionic thiosemicarbazone ligands with N₄S₂ donor set. However, complex 4 is binuclear, and each central Cu(Ⅱ) ion is coordinated by one independent neutral ligand HL and three chloride anions, two of which act as μ²-bridges. In addition, the fluorescence spectra indicate that the interactions of the complex es with DNA, particularly of the complex 4, are stronger than that of the ligand HL.
- quinoline,
- thiosemicarbazone,
- complex,
- crystal structure,
- DNA interaction
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沈阳化工大学材料科学与工程学院沈阳 110142