Citation: LIN Long, LI Xian-Hong, ZHANG Bo, ZHANG Zhan-Ying, WU Wei-Na, WANG Yuan. wo Binuclear Cu(Ⅱ) Complexes with 1-(3-Methylpyrazin-2-yl)ethylidene-4-phenylsemicarbazide: Crystal Structures and DNA Interaction[J]. Chinese Journal of Inorganic Chemistry, ;2017, 33(1): 143-148. doi: 10.11862/CJIC.2016.283 shu

wo Binuclear Cu(Ⅱ) Complexes with 1-(3-Methylpyrazin-2-yl)ethylidene-4-phenylsemicarbazide: Crystal Structures and DNA Interaction

LIN Long ^1,2 ,
LI Xian-Hong ¹ ,
ZHANG Bo ¹ ,
ZHANG Zhan-Ying ¹ ,
WU Wei-Na ^3,*,, ,
WANG Yuan ^3,*,,

1.
School of Materials Science and Engineering, Henan Polytechnic University, Jiaozuo, Henan 454000, China
2.
School of Mathematics and Informatics, Henan Polytechnic University, Jiaozuo, Henan 454000, China
3.
College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, Henan 454000, China

Corresponding author: WU Wei-Na, wuwn08@hpu.edu.cn WANG Yuan, wangyuan08@hpu.edu.cn
Received Date: 15 July 2016
Revised Date: 27 October 2016

Figures(3)

Two binuclear complexes, namely[Cu₂(L)₂Cl₂] (1) and[Cu₂(L)₂(OAc)₂] (2) (where HL is 1-(3-methylpyrazin-2-yl)ethylidene-4-phenylsemicarbazide), have been synthesized and characterized by single crystal X-ray diffraction, elemental analysis and IR spectroscopy. X-ray diffraction analysis results show that in both binuclear complexes, each central Cu(Ⅱ) ion with a distorted square pyramid coordination geometry is surrounded by one independent anionic ligand with N₂O donor set and two coordinated anions (chloride for 1, whilst acetate for 2), one of which acts as a μ²-bridge. In addition, the fluorescence spectra indicate that the interactions of the complexes with DNA are stronger than that of the ligand HL. CCDC:1455421, 1; 1455422, 2.
- semicarbazone,
- Cu(Ⅱ) complex,
- pyrazine,
- crystal structure,
- DNA interaction
1. [1]
  Ye X P, Zhu T F, Wu W N, et al. Inorg. Chem.Commun., 2014,47:60-62 doi: 10.1016/j.inoche.2014.07.022
2. [2]
  Alagesan L, Bhuvanesh N S P, Dharmaraj N. Dalton Trans., 2013,42:7210-7223 doi: 10.1039/c3dt50371b
3. [3]
  CHEN Yan-Min , XIE Qing-Fan, LIU Jin-Hua, et al. Chinese J. Inorg. Chem. , 2015,31:74-80
4. [4]
  Singh P, Singh D P, Singh V P. Polyhedron, 2014,81:56-65 doi: 10.1016/j.poly.2014.05.066
5. [5]
  Nath M, Vats M, Roy P. Eur. J. Med. Chem., 2013,59:310-321 doi: 10.1016/j.ejmech.2012.11.023
6. [6]
  Milenkovi M, Cantoni G, Bacchi A, et al. Polyhedron, 2014, 80:47-52 doi: 10.1016/j.poly.2014.01.022
7. [7]
  Milenkovi M, Bacchi A, Cantoni G, et al. Inorg. Chim. Acta, 2013,395:33-43 doi: 10.1016/j.ica.2012.09.043
8. [8]
  Chang H Q, Jia L, Xu Z Q, et al. Inorg. Chem. Commun., 2015,57:8-10 doi: 10.1016/j.inoche.2015.04.010
9. [9]
  Li M X, Zhang L Z, Yang M, et al. Bioorg. Med. Chem. Lett., 2012,22:2418-2433 doi: 10.1016/j.bmcl.2012.02.024
10. [10]
  Li M X, Zhang L Z, Zhang D, et al. Eur. J. Med. Chem., 2011,46:4383-4390 doi: 10.1016/j.ejmech.2011.07.009
11. [11]
  SHEN Wei, HU Wei-Ji, WU Xiao-Yong , et al. Chinese J. Inorg. Chem. , 2016,32:1101-1110
12. [12]
  Sheldrick G M. SADABS, University of Göttingen, Germany, 1996.
13. [13]
  Sheldrick G M. SHELX-97, Program for the Solution and the Refinement of Crystal Structures, University of Göttingen, Germany, 1997.
14. [14]
  WU Wei-Na, WANG Yuan, TANG Ning . Chinese J. Inorg. Chem. , 2012,28: 425-428
15. [15]
  Nakamoto K. Infrared and Raman Spectra of Inorganic and Coordination Compounds. 4th Ed. New York:Wiley, 1986:257
16. [16]
  Yang Z Y, Wang Y, Wang Y. Bioorg. Med. Chem. Lett., 2007,17:2096-2101 doi: 10.1016/j.bmcl.2006.10.049
1. [1]
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2. [2]
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