Citation: FENG Xiao-Yan, CHEN Ying, LIU Yu-Peng, WANG Chun-Peng, CHU Fu-Xiang. Near-IR Photothermal Antibacterial Effects of Polyethylene Glycol (PEG) Modified Gold Nanorods[J]. Chinese Journal of Inorganic Chemistry, ;2015, (2): 215-221. doi: 10.11862/CJIC.2015.059 shu

Near-IR Photothermal Antibacterial Effects of Polyethylene Glycol (PEG) Modified Gold Nanorods

1.
Institute of Chemical Industry of Forestry Products, CAF China; Key Laboratory of Biomass Energy and Material, Jiangsu Province China; National Engineering Laboratory for Biomass Chemical Utilization China; Key and Open Laboratory on Forest Chemical Engineering, SFA, Nanjing 210042, China

Corresponding author: CHEN Ying,
Received Date: 21 April 2014
Available Online: 2 December 2014
Fund Project: 中央级公益性科研院所基本科研业务费专项资金(No.CAFINT2010K04) (No.CAFINT2010K04)国家自然科学基金(No.31100427) (No.31100427)江苏省自然科学基金(No.BK20131071)资助项目 (No.BK20131071)

Gold nanorods(GNR) with longitudinal surface plasma resonance (LSPR) absorption at 785 nm were synthesized by seed-mediated growth method and their surface was modified with polyethylene glycol (PEG) macromolecular (PEG-GNR). The photothermal conversion effect and cytotoxicity of PEG-GNRwere investigated. Different bacteria, including gram-positive bacterium Staphylococcus aureus and Bacillus cereus, gram-negative bacterium Escherichia coli and Pseudomonas aeruginosa were used to analyze the influences of concentration of PEG-GNRand laser output power on the inhibition effects. The results show that the PEG-GNRhas good antibacterial properties for both Gram positive and negative bacterium under the radiation of near-IRlaser. The concentration of PEG-GNRand laser output power determined antibacterial effects of the PEG-GNR. The preliminary investigation on the antibacterial mechanism was explored by studying of bacteria apoptosis status with fluorescence microscope and transmission electronic microscope, suggesting that the effective absorption of the PEG-GNRby the cells is one of the key factors in the process of photothermal antibiosis.
- gold nanorod;PEG modified;photothermal antibacterial effect
1. [1]
  [1] Coenye T, Vandamme P. Environ. Microbiol., 2003,5(9):719-729
2. [2]
  [2] Nikoobakht B, El-Sayed M A. Chem. Mater., 2003,15(10): 1957-1962
3. [3]
  [3] SONG Wen-Zhi(宋文植), JIANG Ya-Ping(姜雅萍), JI Xiao-Hui(纪小会), et al. Chem. J. Chinese Universities(高等学校化学学报), 2012,33(9):1886-1888
4. [4]
  [4] Jo W, Freedman K, Yi D K, et al. Biofabrication, 2011,3(1): 15002
5. [5]
  [5] Niidome T, Akiyama Y, Yamagata M, et al. J. Biomater. Sci., Polym. Ed., 2009,20(9):1203-1215
6. [6]
  [6] Letfullin R R, Joenathan C, George T F, et al. Nanomedicine, 2006,1(4):473-480
7. [7]
  [7] QU Xiao-Chao(屈晓超), LIANG Jia-Ming(梁佳明), YAO Cui-Ping(姚翠萍), et al. Chin. J. Lasers(中国激光), 2008,34 (11):1459-1465
8. [8]
  [8] ZHENG Ming-Shan(郑明彬), ZHENG Cui-Fang(郑翠芳), GONG Ping(龚萍), et al. Prog. Biochem. Biophys., 2013,40 (10):971-976
9. [9]
  [9] ZHANG Da(张达), ZHOU Fei-Fan(周非凡), XING Da(邢达). Chin. Sci. Bull.(科学通报), 2013,58(7):586-592
10. [10]
  [10] WU Song(吴松), XIAO Shao-Wen(肖绍文), LU Gui-Hua(卢桂花), et al. Chin. J. New Clin. Med.(中国临床新医学), 2013,6(6):531-534
11. [11]
  [11] Kim J W, Shashkov E V, Galanzha E I, et al. Laser. Surg. Med., 2007,39(7):622-634
12. [12]
  [12] Cho E C, Au L, Zhang Q, et al. Small, 2010,6(4):517-522
13. [13]
  [13] Huang W, Tsai P, Chen Y. Nanomedicine, 2007,2(6):777-787
14. [14]
  [14] Guo R, Zhang L, Qian H, et al. Langmuir, 2010,26(8):5428-5434
15. [15]
  [15] Cai W, Gao T, Hong H, et al. Nanotechnol. Sci. Appl., 2008, 3(1):17-22
16. [16]
  [16] Ferrari M. Nat. Rev. Cancer, 2005,5(3):161-171
17. [17]
  [17] Nikoobakht B, El-Sayed M A. Chem. Mater., 2003,15(10): 1957-1962
18. [18]
  [18] Alkilany A M, Murphy C J. J. Nanopart. Res., 2010,12(7): 2313-2333
19. [19]
  [19] Nativo P, Prior I A, Brust M. ACS Nano, 2008,2(8):1639-1644
20. [20]
  [20] Takahashi H, Niidome Y, Niidome T, et al. Langmuir, 2006, 22(1):2-5
21. [21]
  [21] Niidome T, Yamagata M, Okamoto Y, et al. J. Controlled Release, 2006,114(3):343-347
22. [22]
  [22] Cai Z Y, Liu Y J, Lu X M, et al. J. Phys. Chem C, 2013, 117(18):9440-9445
23. [23]
  [23] Niidome T, Ohga A, Akiyama Y, et al. Bioorg. Med. Chem., 2010,18(12):4453-4458
24. [24]
  [24] Dickerson, Erin B, Dreaden, et al. Cancer Lett., 2008,269 (1):57-66
25. [25]
  [25] Moghimi S M, Hunter A C. Trends Biotechnol., 2000,18 (10):412-420
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沈阳化工大学材料科学与工程学院沈阳 110142