Citation: YANG Zi-Yuan, SONG Bin, XU Shou-Wei, ZHENG Chang-Zheng. Synthesis, Crystal Structure and Antibacterial Activities of Furan Acylhydrazone and Its Nickel, Manganese Complexes[J]. Chinese Journal of Inorganic Chemistry, ;2014, 30(3): 585-590. doi: 10.11862/CJIC.2014.095 shu

Synthesis, Crystal Structure and Antibacterial Activities of Furan Acylhydrazone and Its Nickel, Manganese Complexes

1.
1 People's Hospital of Shaanxi Province, Xi'an 710068, China;

Received Date: 19 April 2013
Available Online: 12 November 2013
Fund Project: 西安工程大学博士科研启动基金(No.31004C0402)资助项目。 (No.31004C0402)

A novel Schiff base ligand which called 2-furancarbaldehyde-4-methoxy-benzoylhydrazone (HL) has been synthesized from 2-furancarbaldehyde and 4-methoxybenzoylhydrazine. Two different configurations metal complexes of the ligand which named NiL₂ and Mn(HL)₂Cl₂ were also synthesized in mixed solvent of ethanol and acetone with Ni(NO₃)₂·6H₂O and MnCl₂·4H₂O. The single crystal of HL, NiL₂ and Mn(HL)₂Cl₂ were obtained through solvent evaporation method. Complex NiL₂ and Mn(HL)₂Cl₂ were characterized by using X-ray, EA, FT-IR and 1H NMR methods. Structure analysis shows the ligand HL crystallizes in the trigonal system, space group R3 with a=2.442(2) nm, b=2.442(2) nm, c=1.135 4(10) nm parameters, γ=120°, Z=18. Complex NiL₂ and Mn(HL)₂Cl₂ crystall-izes both in the monoclinic system. Complex NiL₂ has square planar configuration in space group P2₁/n with a=1.206 7(8) nm, b=0.577 4(4) nm, c=1.841 8(13) nm parameters, β=107.122(11)°, Z=2; Complex Mn(HL)₂Cl₂ has distorted octahedral configuration in space group P2₁/c with a=0.915 5(4) nm, b=0.721 7(4) nm, c=2.033 6(9) nm parameters, β=96.047(9)°, Z=2. The ligand and its metal complexes have been screened for their antibacterial activities by agar diffusion method. The result shows that complex NiL₂ has very significant antibacterial activity to Staphylococcus aureus. CCDC: 926194, HL; 926193, NiL₂; 926195, Mn(HL)₂Cl₂.
- Schiff base;crystal structure;antibacterial activity;nickel complex;manganese complex
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沈阳化工大学材料科学与工程学院沈阳 110142