Citation: Shuang Lu, Wei-na Fang, Li-hua Wang, Hua-jie Liu. DNA-assisted High-efficient Purifying and Encoding of Gold Nanotriangles[J]. Acta Polymerica Sinica, ;2019, 50(9): 964-972. doi: 10.11777/j.issn1000-3304.2019.19049 shu

DNA-assisted High-efficient Purifying and Encoding of Gold Nanotriangles

Shuang Lu ^1,2 ,
Wei-na Fang ³ ,
Li-hua Wang ¹ ,
Hua-jie Liu ^4,,

1.
Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800
2.
University of Chinese Academy of Sciences, Beijing 100049
3.
Institute of Molecular Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127
4.
School of Chemical Science and Engineering, Tongji University, Shanghai 200092

Corresponding author: Hua-jie Liu, liuhuajie@tongji.edu.cn
Received Date: 11 March 2019
Revised Date: 22 March 2019
Available Online: 5 May 2019

Combining the advantages of information encoding and function realization, DNA-conjugated nanomaterials have attracted great attention recently. As a typical anisotropic material, gold nano-triangle is of great value due to the sharp vertices. However, the yield of nano-triange is not high through current wet synthesis. In order to solve this problem, we propose a new strategy of shape selective separation of gold nano-triangles with the assist of thiol-DNA. The attachment of DNA to the surface of gold nanoparticles, on one hand, can stabilize the nanoparticles by shielding the direct contact between gold nanoparticles and solution environment. On the other hand, according to the particle shape, size and the surface charge density, gold nanoparticles have different mobilities in the electric field. As a result, gold nanoparticles can be separated by gel electrophoresis. The DNA-assist purification method gives a yield of above 80% of gold nano-triangles, which is also universal for the separation of nano-triangles with different sizes. More importantly, the surface-modified DNA can simultaneously separate and encode gold nano-triangles. By rational designing the DNA sequence, nano-triangles can be assembled on DNA origami and higher-order structures can be constructed.
- Gold nanoparticles,
- Gold nanotriangles,
- DNA,
- Self-assembly,
- Eelectrophoresis,
- Purification
1. [1]
  Kallenbach N R, Ma R I, Seeman N C. Nature, 1983, 305(5937): 829 − 831 doi: 10.1038/305829a0
2. [2]
  Winfree E, Liu F R, Wenzler L A, Seeman N C. Nature, 1998, 394(6693): 539 − 544 doi: 10.1038/28998
3. [3]
  Nummelin S, Kommeri J, Kostiainen M A, Linko V. Adv Mater, 2018, 30(24): 1703721 doi: 10.1002/adma.v30.24
4. [4]
  Jones M R, Seeman N C, Mirkin C A. Science, 2015, 347(6224): 1260901 doi: 10.1126/science.1260901
5. [5]
  Liu X G, Zhang F, Jing X X, Pan M, Liu P, Li W, Zhu B W, Li J, Chen H, Wang L H, Lin J P, Liu Y, Zhao D Y, Yan H, Fan C H. Nature, 2018, 559(7715): 593 − 598 doi: 10.1038/s41586-018-0332-7
6. [6]
  Taton T A, Mirkin C A, Letsinger R L. Science, 2000, 289(5485): 1757 − 1760 doi: 10.1126/science.289.5485.1757
7. [7]
  Saha K, Agasti S S, Kim C, Li X, Rotello V M. Chem Rev, 2012, 112(5): 2739 − 2779 doi: 10.1021/cr2001178
8. [8]
  Liu N, Liedl T. Chem Rev, 2018, 118(6): 3032 − 3053 doi: 10.1021/acs.chemrev.7b00225
9. [9]
  Ding B, Deng Z, Yan H, Cabrini S, Zuckermann R N, Bokor J. J Am Chem Soc, 2010, 132(10): 3248 − 3249 doi: 10.1021/ja9101198
10. [10]
  Lan X, Chen Z, Dai G, Lu X, Ni W, Wang Q. J Am Chem Soc, 2013, 135(31): 11441 − 11444 doi: 10.1021/ja404354c
11. [11]
  Roller E M, Argyropoulos C, Högele A, Liedl T, Pilo-Pais M. Nano Lett, 2016, 16(9): 5962 − 5966 doi: 10.1021/acs.nanolett.6b03015
12. [12]
  Urban M J, Both S, Zhou C, Kuzyk A, Lindfors K, Weiss T, Liu N. Nat Commun, 2018, 9(1): 1454 doi: 10.1038/s41467-018-03882-w
13. [13]
  Nelayah J, Kociak M, Stephan O, de Abajo F J G, Tence M, Henrard L, Taverna D, Pastoriza-Santos I, Liz-Marzan L M, Colliex C. Nat Phys, 2007, 3(5): 348 − 353 doi: 10.1038/nphys575
14. [14]
  Fang Weina(方维娜), Lu Shuang(鲁爽), Wang Lihua(王丽华), Fan Chunhai(樊春海), Liu Huajie(柳华杰). Prog Chem(化学进展), 2017, 29(5): 459 − 466 doi: 10.7536/PC170132
15. [15]
  Zhan P, Wen T, Wang Z G, He Y, Shi J, Wang T, Liu X, Lu G, Ding B. Angew Chem Int Ed, 2018, 57(11): 2846 − 2850 doi: 10.1002/anie.201712749
16. [16]
  Scarabelli L, Coronado-Puchau M, Giner-Casares J J, Langer J, Liz-Marzan L M. ACS Nano, 2014, 8(6): 5833 − 5842 doi: 10.1021/nn500727w
17. [17]
  Liu R, Zhou J H, Zhou Z K, Jiang X, Liu J, Liu G, Wang X H. Nanoscale, 2014, 6(21): 13145 − 13153 doi: 10.1039/C4NR04301D
18. [18]
  Zhang F, Zhu J, An H Q, Li J J, Zhao J W. J Mater Chem C, 2016, 4(3): 568 − 580 doi: 10.1039/C5TC03389F
19. [19]
  Kim J, Song X H, Ji F, Luo B B, Ice N F, Liu Q P, Zhang Q, Chen Q. Nano Lett, 2017, 17(5): 3270 − 3275 doi: 10.1021/acs.nanolett.7b00958
20. [20]
  Kuttner C, Mayer M, Dulle M, Moscoso A, Lopez-Romero J M, Forster S, Fery A, Perez-Juste J, Contreras-Caceres R. ACS Appl Mater Interfaces, 2018, 10(13): 11152 − 11163 doi: 10.1021/acsami.7b19081
21. [21]
  Jones M R, Mirkin C A. Angew Chem Int Ed, 2013, 52(10): 2886 − 2891 doi: 10.1002/anie.201209504
22. [22]
  Chen L, Ji F, Xu Y, He L, Mi Y F, Bao F, Sun B Q, Zhang X H, Zhang Q. Nano Lett, 2014, 14(12): 7201 − 7206 doi: 10.1021/nl504126u
23. [23]
  Rothemund P W K. Nature, 2006, 440(7082): 297 − 302 doi: 10.1038/nature04586
24. [24]
  Fang Weina(方维娜), Fan Chunhai(樊春海), Liu Huajie(柳华杰). Acta Polymerica Sinica(高分子学报), 2017, (12): 1993 − 2000 doi: 10.11777/j.issn1000-3304.2017.17064
25. [25]
  Ha T H, Koo H J, Chung B H. J Phys Chem C, 2007, 111(3): 1123 − 1130 doi: 10.1021/jp066454l
26. [26]
  Millstone J E, Wei W, Jones M R, Yoo H, Mirkin C A. Nano Lett, 2008, 8(8): 2526 − 2529 doi: 10.1021/nl8016253
27. [27]
  Seo D, Il Yoo C, Chung I S, Park S M, Ryu S, Song H. J Phys Chem C, 2008, 112(7): 2469 − 2475 doi: 10.1021/jp7109498
28. [28]
  Lee S H, Salunke B K, Kim B S. Biotechnol Bioproc Eng, 2014, 19(1): 169 − 174 doi: 10.1007/s12257-013-0561-4
29. [29]
  Zheng Y, Feng G, Shang T, Wu W, Huang J, Sun D, Wang Y, Li Q. Sep Sci Technol, 2016, 52(5): 951 − 957
30. [30]
  Li P, Kumar A, Ma J, Kuang Y, Luo L, Sun X. Sci Bull, 2018, 63(10): 645 − 662 doi: 10.1016/j.scib.2018.04.014
31. [31]
  Hanauer M, Pierrat S, Zins I, Lotz A, Sonnichsen C. Nano Lett, 2007, 7(9): 2881 − 2885 doi: 10.1021/nl071615y
32. [32]
  Robertson J D, Rizzello L, Avila-Olias M, Gaitzsch J, Contini C, Magon M S, Renshaw S A, Battaglia G. Sci Rep, 2016, 6: 27494 doi: 10.1038/srep27494
33. [33]
  Zanchet D, Micheel C M, Parak W J, Gerion D, Alivisatos A P. Nano Lett, 2001, 1(1): 32 − 35 doi: 10.1021/nl005508e
34. [34]
  Xia Y, Xiong Y, Lim B, Skrabalak S E. Angew Chem Int Ed, 2009, 48(1): 60 − 103 doi: 10.1002/anie.200802248
35. [35]
  Wu Z, Yang S, Wu W. Nanoscale, 2016, 8(3): 1237 − 1259 doi: 10.1039/C5NR07681A
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