Citation: Zhang Shuo, Cai Chun-hua, Huang Qi-jing, Lin Jia-ping, Xu Zhan-wen. Effect of Intermolecular Interactions on Self-assembled Structures of Polypeptide-based Copolymer/Polystyrene Derivatives Blends[J]. Acta Polymerica Sinica, ;2018, (1): 109-118. doi: 10.11777/j.issn1000-3304.2018.17223 shu

Effect of Intermolecular Interactions on Self-assembled Structures of Polypeptide-based Copolymer/Polystyrene Derivatives Blends

School of Materials Science and Engineering, East China University of Science and Technology, Shanghai Key Laboratory of Advanced Polymeric Materials, Shanghai 200237

Corresponding author: Cai Chun-hua, caichunhua@ecust.edu.cn Lin Jia-ping, jlin@ecust.edu.cn
Received Date: 10 August 2017
Revised Date: 8 September 2017

Herein, poly(γ-benzyl-L-glutamate)-b-poly(ethylene glycol) (PBLG-b-PEG) polypeptide-based rod-coil block copolymer, polystyrene homopolymer (PS), and PS derivatives, such as poly(4-acetoxystyrene) (PAS) homopolymer, poly(vinylphenol) (PVPh) homopolymer, and poly(styrene-co-4-acetoxystyrene) (P(S-co-AS)) copolymer with various AS molar contents, were synthesized. The molecular structures (molecular weight, polydispersity index and composition) of the polymers were characterized by Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance spectroscopy (¹H-NMR) and gel permeation chromatography (GPC). Self-assembly behaviors of the polymer blends composed of PBLG-b-PEG copolymer and PS derivatives (including PS homopolymer) were explored. The self-assembled aggregates were prepared by a dialysis method with water used as selective solvent. The morphologies and structures of the formed aggregates were investigated by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). The influence of intermolecular interaction between polymers (e.g., π-π interaction between PBLG and PS, PAS and PVPh, dipole-dipole interaction between PBLG and PAS, and hydrogen-bonding interaction between PBLG and PVPh) on self-assembly behaviors of the polymer blends was investigated. With the strength of intermolecular interaction increasing in the order of PBLG/PS < PBLG/PAS < PBLG/PVPh, a morphological transition was observed. With relatively weak intermolecular interaction, strip-pattern-spheres were formed in the PBLG-b-PEG/PS blends. For PBLG-b-PEG/PAS blends, as the dipole-dipole interaction was stronger than π-π interaction, the strips disappeared and cavity was observed. As the intermolecular interaction was further enhanced by hydrogen bonding, vesicles were self-assembled in PBLG-b-PEG/PVPh blends. Additionally, the surface morphology of the spherical aggregates was tuned by AS molar content and temperature for PBLG-b-PEG/P(S-co-AS) blends. With increasing AS molar content, the dipole-dipole interaction between PBLG and P(S-co-AS) increased, leading to less regular strip patterns on aggregates surfaces compared with PBLG-b-PEG/PS polymer blends. As temperature increases, the strip patterns became more regular due to the weaker interaction between PBLG and PSAS segments.
- Self-assembly,
- Blends,
- Intermolecular interaction,
- Polypeptides,
- Morphological transition
1. [1]
  Groschel A H, Walther A, Lobling T I, Schacher F H, Schmalz H, Muller A H E. Nature, 2013, 503:247-251 doi: 10.1038/nature12610
2. [2]
  Groschel A H, Muller A H E. Nanoscale, 2015, 7:11841-11876 doi: 10.1039/C5NR02448J
3. [3]
  Zhuang Z L, Jiang T, Lin J P, Gao L, Yang C Y, Wang L Q, Cai C H. Angew Chem Int Ed, 2016, 55:12522-12527 doi: 10.1002/anie.201607059
4. [4]
  Yang C Y, Gao L, Lin J P, Wang L Q, Cai C H, Wei Y H, Li Z B. Angew Chem Int Ed, 2017, 56:5546-5550 doi: 10.1002/anie.201701978
5. [5]
  Cai C H, Lin J P, Lu Y Q, Zhang Q, Wang L Q. Chem Soc Rev, 2016, 45:5985-6012 doi: 10.1039/C6CS00013D
6. [6]
  Xu F G, Wu D D, Huang Y J, Wei H, Gao Y, Feng X L, Yan D Y, Mai Y Y. ACS Macro Lett, 2017, 6:426-430 doi: 10.1021/acsmacrolett.7b00031
7. [7]
  Long Meilin, Zhang Ke, Chen Yongming, Zhu Wen. Acta Polymerica Sinica, 2016, (9):1238-1246
8. [8]
  Lin X, He X H, Hu C Q, Chen Y X, Mai Y Y, Lin S L. Polym Chem, 2016, 7:2815-2820 doi: 10.1039/C6PY00152A
9. [9]
  Mai Y Y, Eisenberg A. Chem Soc Rev, 2012, 41:5969-5985 doi: 10.1039/c2cs35115c
10. [10]
  Wang L Q, Lin J P, Zhang X. Polymer, 2013, 54:3427-3442 doi: 10.1016/j.polymer.2013.03.054
11. [11]
  Zhang Z, Li H D, Huang X Y, Chen D Y. ACS Macro Lett, 2017, 6:580-585 doi: 10.1021/acsmacrolett.7b00296
12. [12]
  Wu Qiong, Xu Pengxiang, Wang Liquan, Cai Chunhua, Lin Jiaping, Lu Yingqing, Tian Xiaohui. Acta Polymerica Sinica, 2017, (3):471-481
13. [13]
  Xu Jiangfei, Zhang Xi. Acta Polymerica Sinica, 2017, (1):37-49
14. [14]
  Liu Y, Lor C, Fu Q, Pan D, Ding L, Liu J, Lu J. J Phys Chem C, 2010, 114:5767-5772 doi: 10.1021/jp9099545
15. [15]
  Huang X J, Xiao Y, Lang M D. J Colloid Interf Sci, 2011, 364:92-99 doi: 10.1016/j.jcis.2011.08.028
16. [16]
  Kakkar D, Mazzaferro S, Thevenot J, Schatz C, Bhatt A, Dwarakanath B S, Singh H, Mishra A K, Lecommandoux S. Macromol Biosci, 2015, 15:124-137 doi: 10.1002/mabi.201400451
17. [17]
  Shan Y B, Luo T, Peng C, Sheng R L, Cao A M, Cao X Y, Shen M W, Guo R, Tomás H, Shi X Y. Biomaterials, 2012, 33:3025-3035 doi: 10.1016/j.biomaterials.2011.12.045
18. [18]
  Qi Meiwei, Huang Wei, Xiao Guyu, Zhu Xinyuan, Gao Chao, Zhou Yongfeng. Acta Polymerica Sinica, 2017, (2):214-228
19. [19]
  Xue J X, Guan Z, Lin J P, Cai C H, Zhang W J, Jiang X Q. Small, 2017, 13:1604214 doi: 10.1002/smll.201604214
20. [20]
  Shao Y, Jia H Y, Cao T Y, Liu D S. Acc Chem Res, 2017, 4:659-668
21. [21]
  Liu Y J, Zhang Y F, Wang Z Y, Wang J, Wei K C, Chen G S, Jiang M. J Am Chem Soc, 2016, 38:12387-12394
22. [22]
  Lua B B, Wei L L, Meng G H, Hou J, Liu Z Y, Guo X H. Chinese J Polym Sci, 2017, 35(8):924-938 doi: 10.1007/s10118-017-1947-0
23. [23]
  Reuther J F, Siriwardane D A, Campos R, Novak B M. Macromolecules, 2015, 48:6890-6899 doi: 10.1021/acs.macromol.5b01564
24. [24]
  Quan C Y, Wu D Q, Chang C, Zhang G B, Cheng S X, Zhang X Z, Zhuo R X. J Phys Chem C, 2009, 113:11262-11267
25. [25]
  Dag A, Zhao J C, Stenzel M H. ACS Macro Lett, 2015, 4:579-583 doi: 10.1021/acsmacrolett.5b00163
26. [26]
  Wu X R, Wu C W, Zhang C. Chinese J Polym Sci, 2017, 35(1):1-24 doi: 10.1007/s10118-017-1871-3
27. [27]
  He C L, Zhuang X L, Tang Z H, Tian H Y, Chen X S. Adv Healthcare Mater, 2012, 1:48-78 doi: 10.1002/adhm.201100008
28. [28]
  Deng C, Wu J T, Cheng R, Meng F H, Klok H A, Zhong Z Y. Prog Polym Sci, 2014, 39:330-364 doi: 10.1016/j.progpolymsci.2013.10.008
29. [29]
  Zhang S S, Li Z B. J Polym Sci, Part B:Polym Phys, 2013, 51:546-555
30. [30]
  Qiu H B, Hudson Z M, Winnik M A, Manners I. Science, 2015, 347:1329-1332 doi: 10.1126/science.1261816
31. [31]
  Cambridge G, GonzalezAlvarez M J, Guerin G, Manners I, Winnik M A. Macromolecules, 2015, 48:707-716 doi: 10.1021/ma502279b
32. [32]
  Cai C H, Lin J P, Zhu X Y, Gong S T, Wang X S, Wang L Q. Macromolecules, 2016, 49:15-22 doi: 10.1021/acs.macromol.5b02254
33. [33]
  Ma Shiying, Wang Rong. Acta Polymerica Sinica, 2016, (8):1030-1041 doi: 10.11777/j.issn1000-3304.2016.16082
34. [34]
  Zhao X J, Yu X L, Lee Y I, Liu H G. Langmuir, 2016, 32:11819-11826 doi: 10.1021/acs.langmuir.6b02396
35. [35]
  Tanaka H, Hasegawa H, Hashimoto T. Macromolecules, 1991, 24:240-251 doi: 10.1021/ma00001a037
36. [36]
  Hashimoto T, TanakaH, Hasegawa H. Macromolecules, 1990, 23:4378-4386 doi: 10.1021/ma00222a009
37. [37]
  Salim N V, Guo Q P. J Phys Chem B, 2011, 115:9528-9536
38. [38]
  Wang X J, Chen J H, Hong K L, Mays J W. ACS Macro Lett, 2012, 1:743-747 doi: 10.1021/mz300192u
39. [39]
  Hickey R J, Luo Q J, Park S J. ACS Macro Lett, 2013, 2:805-808 doi: 10.1021/mz400301g
40. [40]
  Hoheisel T N, Hur K, Wiesner U B. Prog Polym Sci, 2015, 40:3-32 doi: 10.1016/j.progpolymsci.2014.10.002
41. [41]
  Wang Jian, Lu Yuyuan, Xu Yuci, Ruan Yongjin, Li Liangyi, An Lijia. Acta Polymerica Sinica, 2016, (3):271-287 doi: 10.11777/j.issn1000-3304.2016.15340
42. [42]
  Looser J E, Lohmann E, Jiang Y M, Reineke T M, Lodge T P. Macromolecules, 2016, 49:6644-6654 doi: 10.1021/acs.macromol.6b01408
43. [43]
  Huang C W, Mohamed M G, Zhu C Y, Kuo S W. Macromolecules, 2016, 49:5374-5385 doi: 10.1021/acs.macromol.6b01060
44. [44]
  Kuo S W, Chen C J. Macromolecules, 2011, 44:7315-7326 doi: 10.1021/ma200721e
45. [45]
  Hsu C H, Kuo S W, Chen J K, Ko F H, Liao C S, Chang F C. Langmuir, 2008, 24:7727-7734 doi: 10.1021/la703960g
46. [46]
  Osuji C, Chao C Y, Bita I, Ober C K, Thomas E L. Adv Funct Mater, 2002, 12:753-758 doi: 10.1002/adfm.200290003
47. [47]
  Zhang Y Y, Li Y M, Liu W G. Adv Funct Mater, 2015, 25:471-480 doi: 10.1002/adfm.201401989
48. [48]
  Zhang X, Lin J Y, Wang L Q, Zhang L S, Lin J P, Gao L. Polymer, 2015, 78:69-80 doi: 10.1016/j.polymer.2015.09.065
49. [49]
  Dehghan A, Shi A C. Macromolecules, 2013, 46:5796-5805 doi: 10.1021/ma4008576
50. [50]
  Duan C, Li W H, Qiu F, Shi A C. ACS Macro Lett, 2017, 6:257-261 doi: 10.1021/acsmacrolett.7b00058
51. [51]
  Palanisamy A, Guo Q. Chem Commun, 2015, 51:11100-11103 doi: 10.1039/C5CC03714J
52. [52]
  Yang H, Zhang C, Li C, LiuY, An Y, Ma R J, Shi L Q. Biomacromolecules, 2015, 16:1372-1381 doi: 10.1021/acs.biomac.5b00155
53. [53]
  Gong Ying, Yuan Qian, Nie Jing, Yang Shuguang. Acta Polymerica Sinica, 2017, (6):967-973
54. [54]
  Cai C H, Li Y L, Lin J P, Wang L Q, Lin S L, Wang X S, Jiang T. Angew Chem Int Ed, 2013, 52:7732-7736 doi: 10.1002/anie.v52.30
55. [55]
  Zhu X Y, Guan Z, Lin J P, Cai C H. Sci Rep, 2016, 6:29796 doi: 10.1038/srep29796
56. [56]
  Zhang S, Cai C H, Guan Z, Lin J P, Zhu X Y. Chinese Chem Lett, 2017, 28:839-844 doi: 10.1016/j.cclet.2016.12.040
57. [57]
  Kuo S W, Chen C J. Macromolecules, 2012, 45:2442-2452 doi: 10.1021/ma300061w
58. [58]
  Sasaki S, Uzawa T. Polym Bull, 1986, 6:517-524
59. [59]
  Matyjaszewski K, Xia J. Chem Rev, 2001, 101:2921-2990 doi: 10.1021/cr940534g
60. [60]
  Yu Y S, Zhang L F, Eisenberg A. Macromolecules, 1998, 31:1144-1154 doi: 10.1021/ma971254g
61. [61]
  Liu F T, Eisenberg A. J Am Chem Soc, 2003, 125:15059-15064 doi: 10.1021/ja038142r
62. [62]
  Zhang Shuo, Li Qing, Lin Jiaping, Cai Chunhua, Wang Liquan. Acta Polymerica Sinica, 2017, (2):294-305
63. [63]
  LosikM, Kubowicz S, Smarsly B, Schlaad H. Eur Phys J E, 2004, 15:407-411 doi: 10.1140/epje/i2004-10057-5
1. [1]
  Jin Tong , Shuyan Yu . Crystal Engineering for Supramolecular Chirality. University Chemistry, 2024, 39(3): 86-93. doi: 10.3866/PKU.DXHX202308113
2. [2]
  Ruoxi Sun , Yiqian Xu , Shaoru Rong , Chunmiao Han , Hui Xu . The Enchanting Collision of Light and Time Magic: Exploring the Footprints of Long Afterglow Lifetime. University Chemistry, 2024, 39(5): 90-97. doi: 10.3866/PKU.DXHX202310001
3. [3]
  Jiaxun Wu , Mingde Li , Li Dang . The R eaction of Metal Selenium Complexes with Olefins as a Tutorial Case Study for Analyzing Molecular Orbital Interaction Modes. University Chemistry, 2025, 40(3): 108-115. doi: 10.12461/PKU.DXHX202405098
4. [4]
  Shihui Shi , Haoyu Li , Shaojie Han , Yifan Yao , Siqi Liu . Regioselectively Synthesis of Halogenated Arenes via Self-Assembly and Synergistic Catalysis Strategy. University Chemistry, 2024, 39(5): 336-344. doi: 10.3866/PKU.DXHX202312002
5. [5]
  Wenjian Zhang , Mengxin Fan , Wenwen Fei , Wei Bai . Cultivation of Critical Thinking Ability: Based on RAFT Polymerization-Induced Self-Assembly. University Chemistry, 2025, 40(4): 108-112. doi: 10.12461/PKU.DXHX202406099
6. [6]
  Xiaofei NIU , Ke WANG , Fengyan SONG , Shuyan YU . Self-assembly of [Pd₆(L)₄]⁸⁺-type macrocyclic complexes for fluorescent sensing of HSO₃^-. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1233-1242. doi: 10.11862/CJIC.20240057
7. [7]
  Yuxin CHEN , Yanni LING , Yuqing YAO , Keyi WANG , Linna LI , Xin ZHANG , Qin WANG , Hongdao LI , Wenmin WANG . Construction, structures, and interaction with DNA of two Sm^Ⅲ₄ complexes. Chinese Journal of Inorganic Chemistry, 2025, 41(6): 1141-1150. doi: 10.11862/CJIC.20240258
8. [8]
  Huiying Xu , Minghui Liang , Zhi Zhou , Hui Gao , Wei Yi . Application of Quantum Chemistry Computation and Visual Analysis in Teaching of Weak Interactions. University Chemistry, 2025, 40(3): 199-205. doi: 10.12461/PKU.DXHX202407011
9. [9]
  Dongdong Yao , JunweiGu , Yi Yan , Junliang Zhang , Yaping Zheng . Teaching Phase Separation Mechanism in Polymer Blends Using Process Representation Teaching Method: A Teaching Design for Challenging Theoretical Concepts in “Polymer Structure and Properties” Course. University Chemistry, 2025, 40(4): 131-137. doi: 10.12461/PKU.DXHX202408125
10. [10]
  Hailian Tang , Siyuan Chen , Qiaoyun Liu , Guoyi Bai , Botao Qiao , Fei Liu . Stabilized Rh/hydroxyapatite Catalyst for Furfuryl Alcohol Hydrogenation: Application of Oxidative Strong Metal-Support Interactions in Reducing Conditions. Acta Physico-Chimica Sinica, 2025, 41(4): 100036-. doi: 10.3866/PKU.WHXB202408004
11. [11]
  Yanan Jiang , Yuchen Ma . Brief Discussion on the Electronic Exchange Interaction in Quantum Chemistry Computations. University Chemistry, 2025, 40(3): 10-15. doi: 10.12461/PKU.DXHX202402058
12. [12]
  Ji Qi , Jianan Zhu , Yanxu Zhang , Jiahao Yang , Chunting Zhang . Visible Color Change of Copper (II) Complexes in Reversible SCSC Transformation: The Effect of Structure on Color. University Chemistry, 2024, 39(3): 43-57. doi: 10.3866/PKU.DXHX202307050
13. [13]
  Zongfei YANG , Xiaosen ZHAO , Jing LI , Wenchang ZHUANG . Research advances in heteropolyoxoniobates. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 465-480. doi: 10.11862/CJIC.20230306
14. [14]
  Min LIU , Huapeng RUAN , Zhongtao FENG , Xue DONG , Haiyan CUI , Xinping WANG . Neutral boron-containing radical dimers. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 123-130. doi: 10.11862/CJIC.20240362
15. [15]
  Peiyu Zhang , Aixin Song , Jingcheng Hao , Jiwei Cui . 高频超声法制备聚多巴胺薄膜综合实验. University Chemistry, 2025, 40(6): 210-214. doi: 10.12461/PKU.DXHX202407081
16. [16]
  Zhiwen HU , Ping LI , Yulong YANG , Weixia DONG , Qifu BAO . Morphology effects on the piezocatalytic performance of BaTiO₃. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 339-348. doi: 10.11862/CJIC.20240172
17. [17]
  Shipeng WANG , Shangyu XIE , Luxian LIANG , Xuehong WANG , Jie WEI , Deqiang WANG . Piezoelectric effect of Mn, Bi co-doped sodium niobate for promoting cell proliferation and bacteriostasis. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1919-1931. doi: 10.11862/CJIC.20240094
18. [18]
  Qin ZHU , Jiao MA , Zhihui QIAN , Yuxu LUO , Yujiao GUO , Mingwu XIANG , Xiaofang LIU , Ping NING , Junming GUO . Morphological evolution and electrochemical properties of cathode material LiAl_0.08Mn_1.92O₄ single crystal particles. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1549-1562. doi: 10.11862/CJIC.20240022
19. [19]
  Juan Yuan , Bin Zhang , Jinping Wu , Mengfan Wang . Design of a Comprehensive Experiment on Preparation and Characterization of Cu₂(Salen)₂ Nanomaterials with Two Distinct Morphologies. University Chemistry, 2024, 39(10): 420-425. doi: 10.3866/PKU.DXHX202402014
20. [20]
  Meiyu Lin , Yuxin Fang , Songzhang Shen , Yaqian Duan , Wenyi Liang , Chi Zhang , Juan Su . Exploration and Implementation of a Dual-Pathway Blended Teaching Model in General Chemistry Experiment Course: A Case Study of Copper Glycine Synthesis and Its Thermal Analysis. University Chemistry, 2024, 39(8): 48-53. doi: 10.3866/PKU.DXHX202312042

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(111)
HTML views(6)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142