Citation: Xiao-Qiu Dou, Chang-Li Zhao, Nabila Mehwish, Ping Li, Chuan-Liang Feng, Holger Schönherr. Photoresponsive Supramolecular Hydrogel Co-assembled from Fmoc-Phe-OH and 4,4′-Azopyridine for Controllable Dye Release[J]. Chinese Journal of Polymer Science, ;2019, 37(5): 437-443. doi: 10.1007/s10118-019-2223-2 shu

Photoresponsive Supramolecular Hydrogel Co-assembled from Fmoc-Phe-OH and 4,4′-Azopyridine for Controllable Dye Release

a.
Physical Chemistry I and Research Center of Micro and Nanochemistry and Engineering (Cμ), Department of Chemistry and Biology, University of Siegen, Siegen 57076, Germany
b.
State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China

Corresponding author: Chuan-Liang Feng, clfeng@sjtu.edu.cn Holger Schönherr, schoenherr@chemie.uni-siegen.de
Received Date: 11 December 2018
Revised Date: 28 December 2018
Available Online: 18 February 2019

Photoresponsive hydrogels have been attractive because they can provide precise spatial and temporal control for molecule release, whereas the conventional preparation of photoresponsive hydrogels generally involves complex chemical synthesis steps or specific conditions which limits their practical applications. Herein, a new photoresponsive hydrogel is facilely prepared via co-assembly of two simple molecules, Fmoc-Phe-OH and Azp, without chemical synthesis. The co-assembly mechanism, morphology, and photoresponsiveness of (Fmoc-Phe-OH)-Azp hydrogel are investigated by circular dichroism (CD), ultraviolet-visible (UV-Vis), fluorescence, ¹H nuclear magnetic resonance (¹H-NMR), attenuated total internal reflection Fourier transform Infrared (ATR-FTIR) spectroscopy, and scanning electron microscopy (SEM). Furthermore, the enhanced release of encapsulated sulforhodamine B (SRB) dye molecules can be achieved via UV light irradiation. The enhanced dye release amount can be controlled by manipulating photoirradiation time. This study provides a facile way to prepare photoresponsive hydrogel which holds great potential for controllable drug release.
- Photoresponsive,
- Supromolecular,
- Co-assembly,
- Hydrogel,
- Dye release
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