引用本文:
Qin Zheng YANG, Jing YANG, Chang Kai ZHANG. Layered Double Hydroxide as Cordycepin Delivery Nanocarrier[J]. Chinese Chemical Letters,
2006, 17(7): 985-987.
Citation: Qin Zheng YANG, Jing YANG, Chang Kai ZHANG. Layered Double Hydroxide as Cordycepin Delivery Nanocarrier[J]. Chinese Chemical Letters, 2006, 17(7): 985-987.
Citation: Qin Zheng YANG, Jing YANG, Chang Kai ZHANG. Layered Double Hydroxide as Cordycepin Delivery Nanocarrier[J]. Chinese Chemical Letters, 2006, 17(7): 985-987.
Layered Double Hydroxide as Cordycepin Delivery Nanocarrier
摘要:
Layered double hydroxide was investigated as cordycepin delivery nanocarrier for the first time in this study. Negatively charged biomolecule-cordycepin was intercalated in the gallery spaces of [Mg-Al-NO3], which was confirmed by the results of X-ray diffraction and electrophoretic mobility. Cell experiment suggested that the new bio-LDH nanohybrid could prevent cordycepin decomposition by adenosine deaminase. This new formulation could possibly be used as a novel form cordycepin intravenous injection.
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关键词:
- Layered double hydroxide
- / cordycepin
- / nanohybrid
- / intercalate
English
Layered Double Hydroxide as Cordycepin Delivery Nanocarrier
Abstract:
Layered double hydroxide was investigated as cordycepin delivery nanocarrier for the first time in this study. Negatively charged biomolecule-cordycepin was intercalated in the gallery spaces of [Mg-Al-NO3], which was confirmed by the results of X-ray diffraction and electrophoretic mobility. Cell experiment suggested that the new bio-LDH nanohybrid could prevent cordycepin decomposition by adenosine deaminase. This new formulation could possibly be used as a novel form cordycepin intravenous injection.
-
Key words:
- Layered double hydroxide
- / cordycepin
- / nanohybrid
- / intercalate
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