2006 Volume 17 Issue 2

(Salen)Ti(Ⅳ)-Catalyzed Asymmetric Ring-opening of meso Epoxides Using Dithiophosphorus Acid as the Nucleophile
Zheng Hong ZHOU , Zhao Ming LI , Bing LIU , Kang Ying LI , Li Xin WANG , Guo Feng ZHAO , Qi Lin ZHOU , Chu Chi TANG
2006, 17(2): 143-146
[Abstract](224) [FullText HTML] [PDF 42KB](1)
Abstract:
The asymmetric ring-opening of epoxides with dithiophosphorus acids catalyzed by a (salen)Ti(Ⅳ) complex formed in situ from the reaction of Ti(OPr-i)4 and the chiral Schiff base derived from (1R, 2R)-(+)-diaminocyclohexane was realized. The resulting products were obtained with low to good enantioselectivity (up to 73% ee).
First Total Synthesis of 6-Oxodendrolasinolide
Yi LI , Tao ZHANG , Yu Lin LI
2006, 17(2): 147-149
[Abstract](195) [FullText HTML] [PDF 97KB](0)
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An efficient total synthesis of 6-oxodendrolasinolide 1, a new farnesane-based homosesquiterpene lactone, starting from geraniol 2 through twelve steps is described. Our work involved two key steps: (1) regioselective alkylation of the anion of vinyldithian 5 with allylic chloride 31, (2) Corey's oxidative lactionization method2.
Multicomponent Reaction in Ionic Liquid: A Novel and Green Synthesis of 1, 4-Dihydropyridine Derivatives
Xin Ying ZHANG , Yan Zhen LI , Xue Sen FAN , Gui Rong QU , Xue Yuan HU , Jian Ji WANG
2006, 17(2): 150-152
[Abstract](207) [FullText HTML] [PDF 118KB](1)
Abstract:
An efficient and green method for the synthesis of 1, 4-dihydropyridine derivatives mediated in an ionic liquid, [bmim][BF4], through a four-component condensation process of aldehydes, 1, 3-dione, Meldrum's acid and ammonium acetate is disclosed in this paper.
Synthesis of Novel 1-Arylsulfonyl-4-(1'-N-2', 3', 4', 6'-tetra-O-acetyl-β-D-glucopyranosyl)thiosemicarbazides
Yu Xin LI , Zheng Ming LI , Wei Guang ZHAO , Wen Li DONG , Su Hua WANG
2006, 17(2): 153-155
[Abstract](212) [FullText HTML] [PDF 173KB](0)
Abstract:
The synthesis of novel 1-arylsulfonyl -4-(1'-N-2', 3', 4', 6'-tetra-O-acetyl-β-D-glucopyranosyl) thiosemicarbazides via condensation of 2, 3, 4, 6-tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate with substituted phenylsulfonyl hydrazines was described. Their structures and physical properties were confirmed by 1H NMR, 13C NMR spectra, elemental analysis and MS.
Synthesis and Bioassay of 4-Substituted 2-Oxoglutaric Acids
Qiu Yun CHEN , Qing Shan LIU , Christopher J. SCHOFIELD
2006, 17(2): 156-158
[Abstract](199) [FullText HTML] [PDF 48KB](0)
Abstract:
Three 2-oxoglutaric acid analogues were synthesized. Their interaction with factorinhibiting hypoxia-inducible factor (FIH) was studied using LC-MS method. The results show that hydrophobic substitutes of 2-oxoglutaric acids have great influence on their inhibitor activity.
Stereochemistry Control in Direct 1α-Hydroxylation of 5, 6-trans-Vitamin D3 by Solid Support
Yong Bin HAN , Jin Ping CHEN , Bai Ning LIU , Guo Qiang YANG , Yi LI
2006, 17(2): 159-162
[Abstract](203) [FullText HTML] [PDF 144KB](0)
Abstract:
A solid-phase synthesis of 1α-hydroxylation of 5, 6-trans-vitamin D3 8 is described.The solid phase resin acts as a special protecting group, which gives a higher stereoselectivity in oxidation step than classical protecting groups. The stereochemistry control is favored by using high crosslinkage polymer support in a poor solvent. This work may be of benefit to the synthesis of vitamin D system.
First Total Synthesis of 12-Hydroxy-13-methylpodocarpa-9, 11, 13-trien-3-one
Cheng Lu ZHANG , Xiao Lei ZHU , Ying Ge MA , Li Wei ZOU
2006, 17(2): 163-164
[Abstract](206) [FullText HTML] [PDF 110KB](1)
Abstract:
A first facile total synthesis of 12-hydroxy-13-methylpodocarpa-9, 11, 13-trien-3-one 9 was accomplished via a strategy of AC→ABC. In the synthetic process, compound 5 was synthesized through Reimer-Teimann reaction, followed by methylation, reduction, dehydration, addition to ethylene epoxide and chlorination. The target compound 9 was finally obtained through the condensation of Grignard reagent of compound 5 with 6, followed by intramolecular cyclization, reduction and demethylation.
Grignard Addition to Quinoxalinium Salt: Synthesis of 1, 2-Dihydroquinoxaline and 1, 2, 3, 4-Tetrahydroquinoxaline Derivatives
Lian You ZHENG , Xu BAI
2006, 17(2): 165-168
[Abstract](229) [FullText HTML] [PDF 119KB](0)
Abstract:
Grignard additions to a quinoxalinium salt were studied. Depending on the ratio of the reagents and reaction temperature, 1, 2, 3, 4-tetrahydroquinoxaline and 1, 2-dihydroquinoxaline derivatives could be resulted selectively.
Synthesis of Multiester-appended and Multicarboxylic-appended Imidazolium Ionic Liquids
Wei Guo GENG , Xue Hui LI , Le Fu WANG , Hong Li DUAN , Wei Ping PAN
2006, 17(2): 169-172
[Abstract](229) [FullText HTML] [PDF 117KB](0)
Abstract:
Multiester-appended imidazolium ionic liquids were synthesized in a quatemization reaction between the imidazole derivatives carrying single or double esters and ethyl chloroacetate or bromoethane. Multicarboxylic-appended imidazolium ionic liquids were achieved from the hydrolysis of the corresponding ionic liquids. The influences of multifunctional groups on the transition temperatures and viscosity of these new ionic liquids were investigated.
Synthesis and Characterization of a Novel Galactosylated Cholesterol
Shao Ning WANG , Ying Kun QIU , Hui XU , Yi Hui DENG , Da Wei CHEN
2006, 17(2): 173-176
[Abstract](208) [FullText HTML] [PDF 130KB](0)
Abstract:
A novel galactosylated cholesterol with mono-galactoside moiety, (5-cholesten-3-yl)4-oxo-4-[2-(lactobionylamido)ethylamido]butanoate 6 was synthesized. Its chemical structure was characterized by IR, ESI-MS, 13C NMR, 1H NMR. Doxorubicin entrapped in the liposomes containing 10% mol/mol 6 was rapidly accumulated in liver and mainly uptake by parenchymal cells in mice.
A Facile Synthetic Route to L-Phosphinothricin
Xue Song XU , Han Bing TENG , Guo Fu QIU , Shu Cai LIANG , Xian Ming HU
2006, 17(2): 177-179
[Abstract](215) [FullText HTML] [PDF 38KB](3)
Abstract:
A convenient and effective method for synthesis of L-phosphinothricin was described.The highlight was involved in a simple access to the key intermediate L-2-amino-4-chlorobutyric acid derivative from the inexpensive L-methionine.
An Improved and Convenient Procedure for the Synthesis of Ozagrel
Chun GUO , Xiao Dan LIU , Zhen Gang XIE , Chu Jun LI
2006, 17(2): 180-182
[Abstract](206) [FullText HTML] [PDF 113KB](3)
Abstract:
A novel approach to the synthesis of ozagrel is described. The target compound isconveniently prepared from the commercially available material, 1, 1-carboxyldiimidazole (CDI)through the condensation and hydrolyzation.
Total Synthesis of the Analogue of Icogenin
Shu Jie HOU , Peng XU , Liang ZHOU , De Quan YU , Ping Sheng LEI , Chuan Chun ZOU
2006, 17(2): 183-186
[Abstract](205) [FullText HTML] [PDF 90KB](0)
Abstract:
One of the analogues of icogenin, a natural furostanol saponin showing strong cytotoxic effect on cancer cell, was first synthesized via convergent strategy by using diosgenin and available monosaccharides as starting materials.
Synthesis of 11H-Indeno[1, 2-b]qninolines via the Friedländer Reaction
Feng XU , Ding Qiao YANG , Kai Ling JIANG , Wei GUO
2006, 17(2): 187-190
[Abstract](193) [FullText HTML] [PDF 155KB](0)
Abstract:
The nine new 11H-indeno[1, 2-b]quinolines were synthesized in high yield with sodium ethoxide as a catalyst via the Friedänder condensation reaction. The possible reaction mechanism was proposed.
Synthesis and Characterization of Poly (hydroxylethyl, octanediamine)-DL-aspartamide: a New Tissue Engineering Scaffolds
Gu Ping TANG , Xiao Xiao SONG , Da LI
2006, 17(2): 191-194
[Abstract](200) [FullText HTML] [PDF 471KB](0)
Abstract:
Poly (hydroxyethyl, octanediamine)-DL-aspartamide (PHOA) hydrogels were prepared by adding mixture of 1, 8-octanediamine and ethanolamine to PA in DMF at room temperature. The properties of the hydrogels were investigated by FT-IR, 1HNMR, TGA and cell culture assay.
New Triterpenes from Siyekucai (Ixeris chinensis)
Shu Jun ZHANG , Jin Lan WANG , Qi Gang DENG , Masayoshi ANDO
2006, 17(2): 195-197
[Abstract](205) [FullText HTML] [PDF 43KB](0)
Abstract:
Three new triterpenes, 3β, 21α-dihydroxylupen-18(19)-en (1), 3β, 25-dihydroxytirucalla7, 23(24)-dien (2), and 21α-hydroxy-19α-hydrogentaraxasterol-20(30)-en (3) were obtained from an ethyl acetate extract of the whole plant of Siyekucai (Ixeris chinensis). The structures of 1-3 were determined by spectroscopic methods (EIMS, IR, 1D and 2D NMR).
A New Hemiterpene Derivative from Prinsepia utilis
Jun Yi HU , Wei QIAO , Yoshihisa TAKAISHI , Hong Quan DUAN
2006, 17(2): 198-200
[Abstract](199) [FullText HTML] [PDF 141KB](0)
Abstract:
A new hemiterpenoid, (+)-(2R,3S)-2-chloro-3-hydroxy-3-methyl-γ-buty-rolactone was isolated from the leaves of Prinsepia utilis Royle. Its structure was elucidated by spectroscopic methods and X-ray crystallographic analysis.
A New Jatrophane Diterpenoid Ester from Euphorbia turczaninowii
Li Gen LIU , Ren Xiang TAN , You Ming GONG
2006, 17(2): 201-203
[Abstract](200) [FullText HTML] [PDF 107KB](1)
Abstract:
A new jatrophane diterpenoid ester (2S, 3S, 4R, 5R, 7S, 8R, 13R, 15R)-3, 5, 7, 8, 15-pentaacetoxy-9, 14-dioxojatropha-6(17), 11E-diene was isolated from the whole plant of Euphorbia turczaninowii Kar. & Kir.. Its structure was characterized by spectral analysis and confirmed by X-ray crystallographic analysis.
Two New Lanostane-type Triterpenoids from Mulgedium tataricum
Xiao Xiong WANG , Zhong Jian JIA
2006, 17(2): 204-206
[Abstract](199) [FullText HTML] [PDF 117KB](1)
Abstract:
Two new triterpenoids, lanost-9(11), 23Z(24)-diene-3β, 25-diol (1) and lanost-9(11), 25-diene-3β, 24-diol (2) were isolated from Mulgedium tataricum L. Their structures were elucidated by spectral methods.
A Novel Phenylpropanoid-substituted Catechin Glycoside and a New Dihydrochalcone from Sarcandra glabra
Yuan LI , Dong Ming ZHANG , Shi Shan YU , Jian Bei LI , Yong Ming LUO
2006, 17(2): 207-210
[Abstract](204) [FullText HTML] [PDF 104KB](0)
Abstract:
A novel phenylpropanoid-substituted catechin glycoside glabraoside A 1 and a new dihydrochalcone 3'-(7"-allylphenyl)-2', 4', 4"-trihydroxy-6'-methoxydihydrochalcone 2 were isolated from the herbs of Sarcandra glabra. Their structures were elucidated on the basis of spectroscopic analyses and chiroptical methods.
A New Triterpenoid Spaonin Isolated from the Seeds of Aesculus assamica Griff
Hong Wei LIU , Xin Sheng YAO , Nai Li WANG , Guo Ping CAI
2006, 17(2): 211-214
[Abstract](204) [FullText HTML] [PDF 135KB](1)
Abstract:
A new triterpenoid saponin, 21β-angeloylprotoaescigenin-3β-O-[α-L-rhamnopyranosyl(1-3)]β-D-glucopyranosiduronic acid 1, was isolated from the seeds of Aesculus assamica Griff. Its structure was elucidated on the basis of spectroscopic data analysis.
Two New Eremophilenolides from Ligularia muliensis
Qiu Hong WU , He Xiang WANG , Kun GAO
2006, 17(2): 215-217
[Abstract](199) [FullText HTML] [PDF 151KB](0)
Abstract:
Two new eremophilenolides were isolated from the roots of Ligularia muliensis. Their structures were elucidated on the basis of the spectroscopic analysis as 6β-acetoxy-8β-hydroxyl-eremophil-7(11)-en-12, 8α-olide 1 and 6α-hydroxy-8βH-eremophil-7(11)-en-12, 8α-olide 2.
Two New Dihydroflavanoids from Patrinia villosa Juss
Jin Yong PENG , Guo Rong FAN , Yu Tian WU
2006, 17(2): 218-220
[Abstract](196) [FullText HTML] [PDF 153KB](2)
Abstract:
Two new dihydroflavonoids were obtained from the traditional Chinese medicinal herb Patrinia villosa Juss. Their structures were elucidated as (2S)-5, 7, 2', 6'-tetrahydroxy-6, 8-di (γ, γ-dimethylallyl) flavanone (1) and (2S)-5, 7, 2', 6'-tetrahydroxy-6-lavandulylated flavanone (2) by spectroscopic methods including UV, IR, HR-TOF-MS, 1D NMR and 2D NMR techniques.
Thiol-functionalized MCM-48: an Effective Absorbent of Mercury Ions
Shu Guo WANG , Jin Lin LI
2006, 17(2): 221-224
[Abstract](230) [FullText HTML] [PDF 167KB](0)
Abstract:
Mercaptopropyl groups were grafted onto the pore walls of mesoporous molecular sieves MCM-48. The pore structures were characterized by powder X-ray diffraction and N2 adsorption analysis. Elemental analysis confirmed that the material with high organic moiety (2.2 mmol/g) had been obtained. 13C MAS NMR verified the tethered organic groups. The thiol-functionalized MCM-48 showed effective capture of mercury ions, and all of the organic ligands were accessible for the binding of mercury ions.
Behavior and Quantification Studies of Phoxim Pesticide Using Cyclic and Linear Sweep Stripping Voltammetry at a Mercury Electrode
Ping QIU , Yong Nian NI
2006, 17(2): 225-227
[Abstract](221) [FullText HTML] [PDF 84KB](0)
Abstract:
The adsorptive and electrochemical behaviour of phoxim on a hanging mercury drop electrode were explored in NH3·H2O-NH4CL buffer by using cyclic and linear sweep voltmmery The procedure was successfully applied for the assay of phoxim in vegetable and fruit samples.
Thiacrown Molecular Basket with High Extracting Selectivity towards Ag+
Qing Sheng LIU , Shu Ling GONG , Yuan Yin CHEN
2006, 17(2): 228-230
[Abstract](191) [FullText HTML] [PDF 117KB](0)
Abstract:
By bridging 1, 3:4, 6-bis(3, 6-dihydroxy-1, 2-xylylene)tetrahydro-3a, 6a-diphenyl imidazo[4, 5]-imidazole-2, 5(1H, 3H)-dione 1 with S(CH2CH2OCOCH2Cl)2, thiacrown molecular basket 2c was prepared for the first time. It was found that the compound exhibited very poor affinity towards alkali metal ions but high extracting selectivity towards silver ion.
Ionic Liquid and HP-β-CD Modified Capillary Zone Electrophoresis to Separate Hyperoside, Luteolin and Chlorogenic Acid
Yue Ling WANG , Zhong Bo HU , Zhuo Bin YUAN
2006, 17(2): 231-234
[Abstract](182) [FullText HTML] [PDF 61KB](0)
Abstract:
Ionic liquid (1-ethyl-3-methylimidazolium tetrafluoroborate, 1E-3MI-TFB) and HP-β-CD as modifier was added to the buffer to separate hyperoside, luteolin and chlorogenic acid.Experiments explored the effect of concentration of 1E-3MI-TFB and HP-β-CD on separation.The results indicated that 1.0 mmol/L HP-β-CD and 1‰ (v/v) 1E-3MI-TFB added to the buffer simultaneous y could achieve a good compromise of resolution and analysis time. Capillary experiments and UV spectra indicated that there was interaction between 1E-3MI-TFB and analytes.
SBA-15 Modified Carbon Paste Electrode for Rapid cTnI Detection with Enhanced Sensitivity
Nong Yue HE , Hui Shi GUO , Di YANG , Chun Rong GU , Ji Nan ZHANG
2006, 17(2): 235-238
[Abstract](191) [FullText HTML] [PDF 64KB](1)
Abstract:
A novel electrochemical immunoassay for cardiac troponin I (cTnI) combining the concepts of the dual monoclonal antibody "sandwich" principle, the silver enhancement on the nano-gold particle, and the SBA-15 mesoporous modified carbon paste electrode (SBA-MCPE) is described. Four main steps were carried out to obtain the analytical signal, i.e., electrode preparation, immunoreaction, silver enhancement, and anodic stripping voltammetric detection.A linear relationship between the anodic stripping peak current and concentration of cTnI from 0.5 to 5.0 ng/mL and a limit of detection of 0.2 ng/mL of cTnI were obtained.
Synthesis and Characterization of Amphiphilic Block Copolymer Containing PVP and Poly(5-benzyloxytrimethylene carbonate)
Ying Xia WANG , Feng HE , Ren Xi ZHUO
2006, 17(2): 239-242
[Abstract](197) [FullText HTML] [PDF 110KB](0)
Abstract:
Amphiphilic copolymer of 5-benzyloxytrimethylene carbonate (BTMC) with poly (vinyl pyrrolidone) (PVP) was successfully synthesized using immobilized porcine pancreas lipase (IPPL) or SnOct2 as catalyst. Hydroxyl terminated PVP, synthesized with 2-mercaptoethanol as a chain transfer reagent, was employed as a macroinitiator. The resulting copolymers were characterized by GPC, 1H NMR and IR. Increasing the BTMC/PVP-OH feed ratio ([B]/[P])resulted in the increase of Mn of corresponding copolymers and the decrease of Mw/Mn.Immobilized enzyme has comparable catalytic activity to SnOct2 for the copolymerization.
Novel Isatin-Schiff Base Cu (H) and Ni(H) Complexes. X-ray Crystal Structure of Bis[3-(4-hexylphenylimino)-1H-indol-2(3H)-one]-dichlorocopper(H) Complex
Ayse ERCAG , Sema Oztürk YILDIRIM , Mehmet AKKURT , Mahmure Ustün OZGUR , Frank W. HEINEMANN
2006, 17(2): 243-246
[Abstract](216) [FullText HTML] [PDF 135KB](2)
Abstract:
Schiff base ligand (HL) derived from 4-hexylaniline with isatin (1H-indole-2, 3-dione)and its complexes with Cu(Ⅱ), Ni(Ⅱ) were prepared and characterized by analytical, spectroscopic (IR, UV-Vis, Mass) techniques, electrical conductivity, magnetic and thermal measurements. The crystal and molecular structure of [Cu(HL)2Cl2] was determined by a single-crystal X-ray diffraction study. The molecular structure of the title compound has an inversion center on the Cu atom.
Monitor of Polymerization of Inverse Microemulsions Containing Methyl Methacrylate and Acrylic Acid
Xiao LI , Sheng Ping XIA , Wei Jie ZENG , Wei Ying ZHANG , Sheng Xiong DONG
2006, 17(2): 247-250
[Abstract](211) [FullText HTML] [PDF 123KB](0)
Abstract:
The polymerization of the inverse microemulsions composed of methyl methacrylate, acrylic acid, sodium dodecyl sulfate and water was monitored by refractometer, conductometer and time-resolved light scattering device. The results showed that refractive index, conductivity or intensity distribution of scattered light changed along with polymerization, and different processes of polymerization could be identified.
Modification of Nano-alumina Surface by Michael Addition Reaction
Jie ZHANG , Jian YU , Zhao Xia GUO
2006, 17(2): 251-252
[Abstract](204) [FullText HTML] [PDF 55KB](0)
Abstract:
A general method for modification of nano-alumina surface is investigated using Michael addition reaction with α, β-unsaturated carbonyl compounds.
Study on the Interaction of Pd-TMPyP with ctDNA by Solid-substrate Room Temperature Phosphorescence
Li Min GUO , Wen Juan DONG , Chuan DONG
2006, 17(2): 253-254
[Abstract](204) [FullText HTML] [PDF 81KB](0)
Abstract:
The interaction between calf thymus DNA (ctDNA) and Pd (Ⅱ) meso-tetrakis(4-N-methyl pyridiniumyl) porphyrin (Pd-TMPyP) was investigated by steady solid-substrate room temperature phosphorescence (SS-RTP). The SS-RTP intensity and lifetime of Pd-TMPyP enhanced with the increasing ctDNA. The anion quenching experiment of Pd-TMPyP indicated that Pd-TMPyP intercalated into ctDNA, which was also approved by UV-Vis spectra.
Thermoregulated Organic Biphasic Hydrogenation of 1-OcteneCatalyzed by Ru/PETPP Complex
Ya Dong LU , Yan Hua WANG , Zi Lin JIN
2006, 17(2): 255-257
[Abstract](200) [FullText HTML] [PDF 70KB](0)
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Thermoregulated organic biphasic system composed of triethylene glycol monomethyl ether (TGME) and n-heptane was first applied to the hydrogenation of 1-octene. Under the optimal conditions: P(H2)=5.0MPa, T=80℃, t=3h, 1-octene/Ru=1000(molar ratio), the yield of n-octane reached up to 99.6%. Furthermore, the simply decanted catalyst could be reused for 10 times without apparent loss of catalytic activity.
Redox Polymerization of Methyl Methacrylate in the Fluorous Triphasic System
Shi Zhen CHEN , Yun Peng BAI , Zhao Long LI
2006, 17(2): 258-260
[Abstract](186) [FullText HTML] [PDF 53KB](0)
Abstract:
Methyl methacrylate (MMA) was polymerized by using of benzoyl peroxide (BPO) and N, N-dimethylaniline (DMA) as an redox initiator in fluorous triphasic system at room temperature.The polymerization was occurred in both initiator layer and monomer layer in a U-tube. It was found that PMMA obtained from the initiator layer with relatively narrow polydispersity.(PDI=1.38)
Ruthenium Bisphosphine Catalyst on Functionalized Silica:Novel Efficient Catalyst for Carbon Dioxide Hydrogenation to Formic Acid
Yi Ping ZHANG , Jin Hua FEI , Ying Min YU , Xiao Ming ZHENG
2006, 17(2): 261-264
[Abstract](202) [FullText HTML] [PDF 165KB](0)
Abstract:
A novel efficient catalyst for the hydrogenation of carbon dioxide to formic acid ruthenium bisphosphine on functionalized silica was in situ synthesized, affording turnover frequency (TOF) of 1190 h-1 at 100% selectivity under 80C with total pressure of 16.0 MPa. The catalyst can be separated from the reaction mixture easily and reused with moderate loss of activity.
Preparation of Copolymer of Salen-crown Ether Complexes and its Catalytic Activation for Molecular Oxygen
Rong Min WANG , Xiao Dong LI , Yu Feng HE
2006, 17(2): 265-268
[Abstract](179) [FullText HTML] [PDF 213KB](0)
Abstract:
A new stable salen Schiff base cobalt and crown ether sodium complex (SalCo-NaB18C6) was prepared through copolymerization. This copolymer complex was applied to catalytic oxidation of hydrocarbon compound with molecular oxygen without reductant, which was shown the higher activity and selectivity for ketone, and reused effectively.
Metallothionein Induction by Cd(Ⅱ) and Zn(Ⅱ)
Xiao Yan ZHANG , Xin GAO , Yan LI , Xiao Dong FAN
2006, 17(2): 269-272
[Abstract](231) [FullText HTML] [PDF 76KB](0)
Abstract:
The induction of MT(metallothionein) by Cd(Ⅱ) and Zn(Ⅱ) in renal proximal tubule cells (LLC-PKI) and the effects of simultaneous administration of Cd(Ⅱ) and Zn(Ⅱ) on MT induction were discussed. The two metals administered together are able to induce MT to almost 40μg MT/mg protein. The additive production of MT may be due to two different effects by Cd(Ⅱ) and Zn(Ⅱ) on the activation of MT transcription. The experiments of simultaneous administration of Cd(Ⅱ) and Zn(Ⅱ) to the renal proximal tubule cells demonstrated the interaction of these metals, MT induction and proximal tubule toxicity.
Preparation of Langmuir-Blodgett Film of Oligophenylenevinylene at the Air/Water Interface and Study on its Fluorescence
Kai HUANG , Li Chuan MA , Hao Fei GONG
2006, 17(2): 273-276
[Abstract](201) [FullText HTML] [PDF 121KB](0)
Abstract:
Methoxy groups is favorable for film-forming property of oligophenylenevinylenes (OPVs) and the Langmuir-Blodgett film of 1, 4-bis (3, 4, 5-trimethoxystyryl)-2, 5-dimethoxybenzene (MOPV) was prepared. It might be the formation of H-aggregate of MOPV in the LB film that results in a 57 nm blue shift of λmax for the absorption and a 58 nm red shift of λmax for the fluorescence, respectively.
Selective Permeation of CO2 Through Modified PVSA/PS Composite Membrane
Ying ZHANG , Zhi WANG , Juan ZHAO , Ji Xiao WANG , Shi Chang WANG
2006, 17(2): 277-280
[Abstract](197) [FullText HTML] [PDF 128KB](0)
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A new fixed carrier membrane material VSA-SA for CO2 separation was prepared through the chemical modification of PVSA. The selective permeation of CO2 through VSA-SA/PS composite membrane was performed with CO2/CH4 system. The VSA-SA/PS composite membranes possess better CO2 permselectivity than PVSA/PS composite membrane.
Theoretical Study of the Scattering Resonance State, Reaction Mechanism and Partial Potential Energy Surface of the F+CH4→HF +CH3 Reaction
Qiang WANG , Zheng Ting CAI , Da Cheng FENG
2006, 17(2): 281-284
[Abstract](198) [FullText HTML] [PDF 121KB](0)
Abstract:
The partial potential energy surface was constructed by ab initio method [QCISD(T)/6-311++G(2df, 2pd)]for F+CH4→HF+CH3 reaction system. It not only explained the reaction mechanism brought forward by Diego Troya by means of quasiclassical trajectory (QCT) but also successfully validated Kopin Liu's experimental phenomena about the existence of the reactive resonance. The lifetime of the scattering resonance state was about 0.07 ps. All these were in agreement with the experiments.
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