引用本文:
Shi Lei LIU, Xiu Bao DU, Jing Lin KONG. New Polypeptides from Chinese Mistletoe, Viscum coloratum (Kom.) Nakai[J]. Chinese Chemical Letters,
2006, 17(1): 41-44.
Citation: Shi Lei LIU, Xiu Bao DU, Jing Lin KONG. New Polypeptides from Chinese Mistletoe, Viscum coloratum (Kom.) Nakai[J]. Chinese Chemical Letters, 2006, 17(1): 41-44.
Citation: Shi Lei LIU, Xiu Bao DU, Jing Lin KONG. New Polypeptides from Chinese Mistletoe, Viscum coloratum (Kom.) Nakai[J]. Chinese Chemical Letters, 2006, 17(1): 41-44.
New Polypeptides from Chinese Mistletoe, Viscum coloratum (Kom.) Nakai
摘要:
Three viscotoxins have been isolated from Chinese mistletoe, Viscum coloratum (Kom.) Nakai. The primary structures were determined unambiguously by the combination of Edman degradation, endoproteinase Elu-c digestion, and Q-TOF mass spectrometry. One was identified as viscotoxin C1, which was for the first time isolated from Chinese mistletoe. The other two were new polypeptides, named as viscotoxin B5 and viscotoxin B8. Pharmacological studies showed that the polypeptides exhibit distinct cytotoxicity to human cancer cells.
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关键词:
- Viscum coloratum
- / mistletoe
- / isolation
- / primary structure
- / viscotoxin
English
New Polypeptides from Chinese Mistletoe, Viscum coloratum (Kom.) Nakai
Abstract:
Three viscotoxins have been isolated from Chinese mistletoe, Viscum coloratum (Kom.) Nakai. The primary structures were determined unambiguously by the combination of Edman degradation, endoproteinase Elu-c digestion, and Q-TOF mass spectrometry. One was identified as viscotoxin C1, which was for the first time isolated from Chinese mistletoe. The other two were new polypeptides, named as viscotoxin B5 and viscotoxin B8. Pharmacological studies showed that the polypeptides exhibit distinct cytotoxicity to human cancer cells.
-
Key words:
- Viscum coloratum
- / mistletoe
- / isolation
- / primary structure
- / viscotoxin
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