2005 Volume 16 Issue 7

A Ferrocenylsulfide-mediated Sulfur Ylide Epoxidation Reaction
Lei WANG , Zhi Zhen HUANG
2005, 16(7): 853-855
[Abstract](200) [FullText HTML] [PDF 1083KB](0)
A ferrocenylsulfides 1-2 mediated sulfur ylide epoxidation reaction was found to stereoselectively afford trans-oxiranes in excellent yields with recoverable starting material.
The Self-catalytic Esterification Reaction of O-Phosphoryl Serine Derivative
Jin Tang DU , Yan Mei LI , Zhong Zhou CHEN , Shi Zhong LUO , Yu Fen ZHAO
2005, 16(7): 856-858
[Abstract](189) [FullText HTML] [PDF 1061KB](0)
O-Phosphoryl serine derivative can perform self-catalytic esterification reaction in the mixture of CH3OH and CHCl3 at the room temperature. The phosphoryl group participation was the key step of the esterification. This type of reactions were proposed through an intermediate of mixed phosphoric-carboxylic anhydride that might provide a clue to the function of the phosphoryl group in the phosphorylated enzymes and in the prebiotic synthesis of protein.
Novel Bone-targeted Agents for Treatment of Osteoporosis
Jun Bo WANG , Chun Hao YANG , Xue Ming YAN , Xi Han WU , Yu Yuan XIE
2005, 16(7): 859-862
[Abstract](204) [FullText HTML] [PDF 1240KB](2)
The novel bone-targeted agents were designed and synthesized by the combination of raloxifene and bisphosphonates. The anti-osteoporosis effect was evaluated by bone mineral density (BMD) obtained from OVX mice in vivo. The results indicated that the compound 8, 9 not only prevented ovariectomy induced loss of bone but also enhanced BMD to 0.87% and 19.67% compared to Sham, respectively.
Synthesis and Crystal Structures of Schiff Bases Bearing Ferrocenylphenyl Groups
Yan XU , Yong FU , Mao Ping SONG , Yang Jie WU
2005, 16(7): 863-866
[Abstract](196) [FullText HTML] [PDF 1377KB](0)
The Schiff bases bearing ferrocenylphenyl and diferrocenylphenyl groups were synthesized by the reactions of m-ferrocenylaniline with salicylaldehyde or 1, 4-bis (2'-formylphenyl)-1, 4-dioxabutane. The title compounds were characterized by elemental analysis, IR, 1H NMR and X-ray structural determination.
Synthesis of Boswellic Acid Derivatives and Primary Research on their Activities
Yan Qiu MENG , Lin Xiang ZHAO , Zan WANG , Dan LIU , Yong Kui JING
2005, 16(7): 867-870
[Abstract](196) [FullText HTML] [PDF 1721KB](0)
In order to search for new potent anti-cancer agents, a series of boswellic acid derivatives were designed and synthesized. Six of them were identified by IR, NMR and MS as new compounds and biologic assay of anti-cancer is underway.
Photosensitization of trans-Vitamin D3 to cis-Vitamin D3 in Heterogeneous System
Yong Bin HAN , Jin Ping CHEN , Yun Yan GAO , Bai Ning LIU , Guo Qiang YANG , Yi LI
2005, 16(7): 871-874
[Abstract](222) [FullText HTML] [PDF 1407KB](0)
Two modes of heterogeneous photoisomerization of trans-vitamin D3 to cis-vitamin D3are described. The occurrence of isomerization on the substrate bounded to the polymeric support gives us the possibility in succession synthesis of 1α-hydroxyvitamin D3. The polymer-bound anthracene can sensitize isomerization of trans-vitamin D3 to cis-vitamin D3 efficiently and ease the separation process.
A New and Efficient Synthetic Method and Antibacterial Activities of Oxazolidinone Analogues
De Sheng YU , Liang HUANG , Hui LIANG , Ping GONG
2005, 16(7): 875-878
[Abstract](188) [FullText HTML] [PDF 1202KB](6)
A series of novel oxazolidinone analogues were prepared by a new and efficient synthetic method and their antibacterial activities were determined. These compounds were characterized by LC-MS and 1H NMR.
Exploration of Chiral Aminophenols and Aminonaphthols with C2-Symmetry
Yan SUN , Zhi Min LI , Xiu Min SHE N , Feng Nian MA , Cong ZHANG
2005, 16(7): 879-882
[Abstract](183) [FullText HTML] [PDF 1105KB](0)
The exploration of C2-symmetric chiral aminophenols and aminonaphthols is described.Seven new ligands have been successfully synthesized using Mannich reaction as a key step.Four of them have C2-symmetry and their structure has been fully characterized by means of NMR and X-ray crystallography.
Synthesis and Crystal Structure of a Novel Hetero-six-nuclear Copper-iron Cluster Containing Ferroceylphenyl Groups
Yan XU , Hai Xian WANG , Yong FU , Mao Ping SONG , Yang Jie WU
2005, 16(7): 883-885
[Abstract](178) [FullText HTML] [PDF 1314KB](0)
A new hetero-six-nuclear cluster was synthesized and determined by X-ray diffraction technique. The four-carboxylate groups are bound to the Cu(Ⅱ) atoms to form Cu(OR)4Cu paddle-wheel-type cage between two DMF as the basis for the cluster. The distance of two copper(Ⅱ) atoms is 2.642 Å, and they are bridged by the carboxylate groups. A huge system plane was auto-assembled by four host molecules and two Cu (Ⅱ) ions, which was observed in the crystal structure.
An Efficient and Green Synthesis of 5-Oxo-5,6,7,8-tetrahydro 4H-benzo-[b]-pyran Derivatives Promoted by InCl3·4H2O Under Microwave Irradiation
Xue Yuan HU , Xue Sen FAN , Xin Ying ZHANG , Gui Rong QU , Yan Zhen LI
2005, 16(7): 886-888
[Abstract](170) [FullText HTML] [PDF 1151KB](0)
A rapid and facile preparation of benzo-[b]-pyran derivatives through condensation of chalcone and 5, 5-dimethyl-1,3-cyclohexandione under microwave irradiation in the presence of catalytic amount of InCI3·4H2O has been developed.with its high effciency,operational simplicity and environmental benignancy, this method may provide a useful alternative for the preparation of benzo-[b]-pyran derivatives.
Synthesis of 4-Aminosalicylglycine
Zheng Bao ZHAO , Jing GUO , Yuan Gui WEI , Tong Da LIANG
2005, 16(7): 889-892
[Abstract](178) [FullText HTML] [PDF 1551KB](0)
To search for a better prodrug of 4-aminosalicylic acid that is expected to deliver stably parent drug to colon against the inflammatory bowel disease, a novel 4-aminosalicylic acid derivative was designed and synthesized from 4-aminosalicylic acid. 4-Aminosalicylglycine was prepared from 4-aminosalicylic acid by protecting amino and hydroxyl groups with benzyloxycarbonyl and acetyl, respectively, then the carboxylic acid was converted to acyl chloride which was treated with glycine. After removing the protection groups, 4-aminosalicylglycine was obtained. All the compounds were characterized by FT-IR, 1H-NMR, 13C-NMR spectra. In vivo experiment on rats suggested that the curative effect of 4-aminosalicylglycine was more effective than that of 4-aminosalicylic acid.
Reduction of 1-Deoxy-13-oxotaxanes
Meng ZHANG , Da Li YIN , Ji Yu GUO , Xiao Tian LIANG
2005, 16(7): 893-896
[Abstract](177) [FullText HTML] [PDF 1401KB](0)
Reduction of 1-deoxy-13-oxotaxanes has been studied under different reaction conditions.Some interesting reactions were reported.
FeCl3·6H2O Catalyzed Reaction of Aromatic Aldehydes with 5, 5-Dimethyl-1, 3-cyclohexandione in Ionic Liquids
Xue Sen FAN , Yan Zhen LI , Xin Ying ZHANG , Xue Yuan HU , Jian Ji WANG
2005, 16(7): 897-899
[Abstract](183) [FullText HTML] [PDF 1177KB](2)
The reaction of aromatic aldehydes 1 with 5, 5-dimethyl-1, 3-cyclohexandione 2 was investigated in this paper by using[bmim] [BF4] as the reaction medium. It was found that when the reaction was carried out in the presence of catalytic amount of FeCl3·6H2O, xanthenediones 3 was obtained in high yields. On the other hand, when a combination of trimethylchlorosilane (TMSCl) and FeCl3·6H2O was employed as the catalyst, the reaction afforded ring-opening derivatives of xanthenediones 4 with high efficiency.
One-step Synthesis of Dipyrromethanes in the Presence of Ionic Liquid[Hmim]BF4
Guo Hua GAO , Liang LU , Jin Bao GAO , Wen Juan ZHOU , Jian Guo YANG , Xin Yu YU , Ming Yuan HE
2005, 16(7): 900-902
[Abstract](178) [FullText HTML] [PDF 1048KB](1)
Dipyrromethanes were obtained in moderate yields by the condensation of ketone and pyrrole in the presence of ionic liquid[Hmim]BF4 without using any strong acid and other organic solvent.
Organic Reactions in Ionic Liquids:An Efficient Method for the Synthesis of Phenacyl Esters by Reaction of Carboxylic Acids with α-Bromoacetophenone Promoted by Potassium Fluoride
Yi HU , Jue CHEN , Zhang Gao LE , Zhen Chu CHEN , Qin Guo ZHENG
2005, 16(7): 903-905
[Abstract](177) [FullText HTML] [PDF 1281KB](1)
An efficient method is reported for the synthesis of phenacyl esters by reaction of carboxylic acids with α-bromoacetophenone promoted by potassium fluoride in ionic liquid[Bmim]PF6, the yield of the reaction is almost quantitative and the products are essentially pure.
A Novel Ionic Liquid/water Biphasic System for the Preparation of Oximes
Hui Mou LUO , Yi Qun LI , Wen Jie ZHENG
2005, 16(7): 906-908
[Abstract](171) [FullText HTML] [PDF 1179KB](0)
A variety of carbonyl compounds can be converted into oximes efficiently and conveniently in a novel ionic liquid/water bi-phasic system in the presence of sodium bicarbonate at ambient temperature. The ionic liquid 1-butyl-3-methyl imidazolium hexafluorophosphate[bmim]PF6 is immiscible with water or diethyl ether and can be easily recycled for reuse without noticeable droping in activity after separation of the products. The protocol is rapid, the yields are excellent, the method is simple and the ionic liquid can be reused.
Preparation of 3-Aryl-5-phenylselenomethyl 1, 2, 4-Oxadiazole and their Further Deselenenylation Reaction
Wei Ming XU , Mao Zhong MIAO , Jian Feng XU , Xian HUANG
2005, 16(7): 909-910
[Abstract](184) [FullText HTML] [PDF 579KB](2)
A mild Porco's two-step, one-pot condensation reaction for the preparation of 3-aryl-5-phenylselenomethyl 1, 2, 4-oxadiazole through phenylseleno acetic acid and benzamidoxime was reported. And further deselenenylation of 3-aryl-5-phenylselenomethyl 1, 2, 4-oxadiazole was studied.
Spirostane Steroidal Saponins from the Undergroud Parts of Tupistra chinensis
Guang Xu WU , Xiao Yi WEI , Wei Xin CHEN
2005, 16(7): 911-914
[Abstract](175) [FullText HTML] [PDF 1496KB](1)
Two new spirostanol saponins, (25S)-spirostane-1β,3β,5β-triol 3-O-β-D-glucopyranoside 1 and rhodeasapogenin 3-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranoside 2, together with a known saponin, rhodeasapogenin 3-O-β-D-glucopyranoside 3, were isolated from the underground parts of Tupistra chinensis Bak.. Their structures were determined by spectroscopic analysis.
A New Sesquiterpene from the Roots of Biondia hemsleyana
Xing Gen TAN , Pei CAO , Shu Lin PENG , Li Sheng DING
2005, 16(7): 915-917
[Abstract](183) [FullText HTML] [PDF 987KB](0)
A new sesquiterpene with a unusual modified germacrane skeleton was isolated from the ethanol extracts of the roots of Biondia hemsleyana and its structure was elucidated as 3β-hydroxy4,14-cyclogermacra-11-en-9-one by the spectroscopic methods and X-ray crystallography.
A New Coumestan from Arachis hypogaea L.
Hong Wei FU , Hai Long ZHANG , Yue Hu PEI
2005, 16(7): 918-920
[Abstract](168) [FullText HTML] [PDF 788KB](0)
A new coumestan, 3, 9-dihydroxy-4, 8-dimethoxycoumestan, was isolated from Arachis hypogaea L. together with two known compounds:3, 9-dihydroxy-4-methoxycoumestan and 3,9-dihydroxy-8-methoxycoumestan. The structure was established by spectroscopic methods.
A New Diterpene Acid from the Flowers of Heteropappus altaicus
Qing Hua LIU , Jun Shan YANG , Yang LU , Qi Tai ZHENG , Li MAO
2005, 16(7): 921-924
[Abstract](175) [FullText HTML] [PDF 1096KB](1)
A new compound, named heteraltaic acid was isolated from the flowers of Heteropappus altaicus (willd) Novopokr.. The compound was elucidated as (5R, 6S, 8aS)-5-[2-(3-furyl) ethyl-5, 6, 8a-trimethyl-4a, 5, 6, 7, 8, 8a-hexahydro-1-naphthalenecarboxylic acid]by the combination of 1D and 2D NMR techniques (HSQC, HMBC) and X-ray analysis.
Chlorophytoside A, a New Labdane Diterpene Glycoside from Chlorophytum laxum
You Heng GAO , Quan Xi MEI , Hui Fei WU , Yuan Ming DIAO , Xin Sheng PENG , Rui Fang ZHANG
2005, 16(7): 925-927
[Abstract](185) [FullText HTML] [PDF 949KB](3)
A new labdane-type diterpene glycoside 1, chlorophytoside A, had been isolated from Chlorophytum laxum R.Br. The structure had been elucidated as (10S)-6α-hydroxylabda-8,13-dien-15,16-olide 3R-O-β-D-glucopyranoside on the basis of chemical and spectroscopic data.
Two New Glycosides from the Roots of Ranunculus ternatus
Jing Kui TIAN , Feng SUN , Yi Yu CHENG
2005, 16(7): 928-930
[Abstract](181) [FullText HTML] [PDF 929KB](0)
Two new glycosides named as ternatoside A 1 and ternatoside B 2 were isolated from the roots of Ranunculus ternatus, the structures were determined by 1D and 2D NMR, ESI-MS techniques, and chemical methods.
Spectrophotometric Study on the Interaction of Water with Chloranilic Acid and its Analytical Application
Feng Lin ZHAO , Xi Lan FENG , Xue Jing LIU , Na LI , Ke An LI
2005, 16(7): 931-934
[Abstract](177) [FullText HTML] [PDF 1584KB](2)
The reaction between chloranilic acid and water in alcohol was studied spectrophotometrically. The conditions of reaction were investigated in detail. The stable purple complex with an absorption wavelength at 530 nm was produced from the reaction between chloranilic acid and water. As a method for determination of H2O, Beer's law was obeyed in range of 0-6.0% or 0-8.0% (V/V) with the detection limit of 0.13%. The relative standard deviation (RSD) was less than 2%. The proposed method has been applied to determination of trace amount of water in ethanol, flour and food flavoring, respectively. The recoveries of water in samples were 97~102%.
A Novel Method for Conversion of Valuable BDS Intermediates HPBS/Cx-HPBS from DBT/Cx-DBT
Bo YU , Jian HUANG , Xiao Feng CAI , Xiao Yong LIU , Cui Qing MA , Fu Li LI , Ping XU
2005, 16(7): 935-938
[Abstract](181) [FullText HTML] [PDF 1462KB](0)
A simple recombinant PCR method was used to delete the dszB gene responsible for the slowest step of the Dsz pathway and allow the accumulation of hydroxyphenyl benzene sulfinate (HPBS) in the recombinant E. coli. Using GC/MS, HPBS accumulation was confirmed. The recombinant E. coli could also desulfurize Cx-DBT to corresponding Cx-HPBS. The result gave a new insight to BDS process and explored a new method to obtain valuable surfactants from cheap raw materials.
Fourier Power Spectrum Analysis of Exons for the Period-3 Behavior
Yuan Xin TIAN , Chao CHEN , Xiao Yong ZOU , Jian Ding QIU , Pei Xiang CAI , Jin Yuan MO
2005, 16(7): 939-942
[Abstract](169) [FullText HTML] [PDF 1557KB](0)
The period-3 behaviors of 105 exons from 20 genes in human were studied by Fourier power spectrum. The results indicated that not all exons show the period-3 behavior. The exons were adjusted in order to make them accord with the order of the protein translated, and we found that the period-3 character is relation to the length of exons and the bases distribution in the three codon position. Furthermore, as long as the exons with period-3 behavior accord with the order of protein translated, they would exhibit the synonymous codons usage preference, and the codons with g/c at the third position are used in higher frequency. The results are significant to the gene prediction and the research on the introns.
Interaction of Surface-active Fluorescence Probes with Bovine Serum Albumin
Tong Kuan XU , Xing Hai SHEN , Na LI , Hong Cheng GAO
2005, 16(7): 943-946
[Abstract](180) [FullText HTML] [PDF 1194KB](0)
The binding between three surface-active substituted 3H-indole fluorescence probes and bovine serum albumin (BSA) in aqueous solution was studied using fluorescence quenching. The binding constants of 3H-indole molecules with BSA were obtained. According to the Forster resonance energy transfer theory, the distances between 3H-indole molecules and tryptophan of BSA were calculated. The results show that the oligoethyloxyethylene chain of 3H-indole molecules is longer, the binding between them is stronger, the energy transfer efficiency is higher,and the distance between tryptophan and 3H-indole is nearer.
The Interaction between Propranolol and Gold Nanoparticles and its Analytical Application
Hong Ying DUAN , Fang CHEN , Xin Ping AI , Zhi Ke HE
2005, 16(7): 947-950
[Abstract](367) [FullText HTML] [PDF 1539KB](2)
The addition of propranolol induced the aggregation of gold nanoparticles, and increased Rayleigh light scattering (RLS) intensity greatly. The interaction between them was studied by RLS spectrum, UV-Vis spectrum and transmission electron microscopy (TEM). Based on these results, a novel method was proposed for propranolol assay. With the combination of solid phase microextraction (SPME), the proposed method was successfully applied to determine propranolol in urine.
A Novel Biomolecular Immobilization Matrix Based on Nanoporous ZnO/Chitosan Composite Film for Amperometric Hydrogen Peroxide Biosensor
Yun Hui YANG , Ming Hui YANG , Jian Hui JIANG , Guo Li SHEN , Ru Qin YU
2005, 16(7): 951-954
[Abstract](190) [FullText HTML] [PDF 1588KB](0)
A novel ZnO/Chitosan composite matrix was developed to fabricate the H2O2 biosensor.This material combined the advantages of inorganic species, ZnO, and organic polymer, chitosan.Horseradish peroxidase immobilized in the material maintained its activity well as the usage of glutaraldehyde was avoided. The activity of enzyme was 7.9 times greater than the cross-linked enzyme. The parameters affecting the fabrication and experimental conditions of biosensors were optimized. With the aid of hydroquinone mediator, the biosensor had a fast response of less than 10s. The linear range was 5.0×10-6 to 2.0×10-3 mol/L with a sensitivity of 43.8 μAL/mmol.This matrix can also be used to immobilize other biomolecule.
Preparation and Evaluation of Molecularly Imprinted Monolithic Column for Felodipine in Micro-liquid Chromatography
Qi Liang DENG , Zhi Hong LUN , Chao YAN , Ru Yu GAO
2005, 16(7): 955-958
[Abstract](160) [FullText HTML] [PDF 1387KB](0)
This study concentrated on the production of molecularly imprinted polymers (MIPs) as highly selective sorbents for felodipine (FLD), a representive dihydropyridine calcium antagonists.Demonstrated chromatographically through a selection factor, these MIPs showed high selectivity for the template molecule among a group of structurally similar compounds. The recognition was found to correlate with structural similarity to the template compound.
Synthesis and Characterization of Benzimidazolium Salts as Novel Ionic Liquids and their Catalytic Behavior in the Reaction of Alkylation
Wei Guo HUANG , Bo CHEN , Yuan Yuan WANG , Li Yi DAI , Yong Kui SHAN
2005, 16(7): 959-962
[Abstract](181) [FullText HTML] [PDF 1434KB](1)
A new series of ionic liquids have been prepared containing benzimidazolium cation (abbreviated as Bim). These salts were characterized by DSC, NMR, elemental analysis and thermogravimetric analysis. They showed different properties compared to imidazolium cation due to the introduction of benzene ring. The alkylation of benzene/diphenyl ether with 1-dodecene was carried in C4eBimBr-AlCl3 ionic liquids showing high catalytic activity when the mole ratio of C4eBimB:AlCl3 was 1:2.
Study on the Surface Property of Surfactant Ionic Liquids Solutions
Yan An GAO , Zhong Ni WANG , Jin ZHANG , Wan Guo HOU , Gan Zuo LI , Bu Xing HAN , Feng Feng Lü , Gao Yong ZHANG
2005, 16(7): 963-966
[Abstract](172) [FullText HTML] [PDF 1573KB](1)
The surfactant TX-100 can be dissolved in ionic liquid bmimPF6 and decrease the surface tension of 1-butyl-3-methylimidazolium hexafluorophosphate (bmimPF6) solutions. Here,we confirmed that in this new system, the pure solvents need rearrangement at the air-water interface at the initial stage. The dynamic surface tension (DST) study shows that at the initial adsorption stage, the adsorption model of surfactant accords with the diffusion-controlled adsorption mechanism, and the dilute ionic liquids solutions is further close to the diffusion-controlled adsorption.
A Novel Nanocrystalline TiO2 Thin Film Electrodes Prepared at Low Temperature
Cheng Yu LI , Xue Ping LI , Yu Tao MA , Zheng Ping WANG , Xiao Wen ZHOU , Yuan LIN , Shu Jing FENG , Xu Rui XIAO
2005, 16(7): 967-970
[Abstract](188) [FullText HTML] [PDF 1528KB](0)
Nanocrystalline TiO2 thin films were successfully prepared by a new "water-cooked" method on both conductive glass substrates and flexible substrates at low temperature.Dye-sensitized solar cells based on these films have exhibited high overall light-to-electricity conversion efficiencies of 4.67% and 1.94% on conductive glass substrate and flexible substrate,respectively, under the illumination at 100 mW/cm2.
Thermal Behavior of Poly(trimethylene-co-ethylene terephthalate)
Yong XU , Sheng Rong YE , Jin Wen QIAN
2005, 16(7): 971-974
[Abstract](175) [FullText HTML] [PDF 1500KB](0)
Poly (trimethylene-co-ethylene terephthalate) with various compositions of diol has been synthesized. The crystallization of copolyesters with high comonomer content was observed by both wide-angle X-ray diffraction (WAXD) and differential scanning calorimetry (DSC). It was found that the copolyesters become less crystallizable with the involvement of the comonomer,the crystals of crystallizable copolyesters come from PTT or PET homopolymers. The glass transition temperature (Tg) of the copolyester increases with increasing PET component in the copolyester, and the relationship between Tg and composition obey both Fox equation and additive law, the former is better in describing this relationship.
Asymmetric Phase-transfer Mediated Epoxidation of α,β-Enones Using Dendritic Catalysts Derived from Cinchona Alkaloids
Xu Dong LIU , Xiao Li BAI , Xue Peng QIU , Lian Xun GAO
2005, 16(7): 975-978
[Abstract](176) [FullText HTML] [PDF 1500KB](0)
Chiral phase-transfer catalysts, derived from cinchona alkaloids and Frechet dendritic wedges up to generation two, have been synthesized. These chiral dendritic molecules have been used as PTCs in the epoxidation of α,β-enones, showing a moderate level of asymmetric induction.
Photorechargeable Properties of Metal Hydride-SrTiO3 Electrode
Wen Kui ZHANG , Xi Li TONG , Hui HUANG , Yong Ping GAN , Na HUANG
2005, 16(7): 979-982
[Abstract](192) [FullText HTML] [PDF 1416KB](0)
A photosensitive metal hydride electrode was prepared by modification with perovskite-type SrTiO3 photocatalyst. The photorechargeable properties of the prepared electrodes were investigated by using electrochemical cyclic voltammetry and EIS measurements. The results showed that the modified electrode exhibited the obvious photorechargeable properties. The reduction current increased remarkably under the xeon light irradiation compared with the unmodified electrode. During the photocharging process, the potential of the modified electrode shifted quickly to negative direction and a potential plateau of about -0.90V (vs. Hg/HgO) occurred at the end of light irradiation. The corresponding discharge capacity of the electrode was about 5.4 mAh/g.
A Novel Reagentless Biosensor Constructed by Layer-by-Layer Assembly of HRP and Nile Blue Premixed with Polyanion
Shao Ming YANG , Yang Mei LI , Xiu Ming JIANG , Xian Fu LIN
2005, 16(7): 983-986
[Abstract](177) [FullText HTML] [PDF 1355KB](0)
A novel reagentless biosensor constructed by the organic dye nile blue (NB) and horseradish peroxidase (HRP) has been fabricated via layer-by-layer (LBL) self-assembly technique. NB premixed with polyanion poly (sodium-p-styrenesulfonate) (PSS) acts as the mediator between the immobilized HRP and the electrode surface. The response of the biosensor to hydrogen peroxide has been investigated. The linear range of the biosensor to hydrogen peroxide was from 0.20 mmol/L to 7.03 mmol/L with a sensitivity of 8.45 μA/(mmol/L).
Role of the Confined Geometry on the Crystallization of Poly(ethylene terephthlate) Ultrathin Films
Ying ZHANG , Yong Lai LU , De Yan SHEN
2005, 16(7): 987-990
[Abstract](185) [FullText HTML] [PDF 1387KB](0)
The reflection-absorption infrared (RAIR) was employed to study the crystallization kinetic of poly (ethylene terephthalate) (PET) ultrathin films. During isothermal crystallization the thinner PET film shows a slower kinetic compared with the thicker film. Moreover, the final crystallinity of films with various thickness was found decrease with thickness. The result of fitting our data to Avrami equation showed that the Avrami exponents decrease with film thickness.
Preparation and Blood Compatibility of Oxidized-chitosan Films
Yue Dong YANG , Jiu Gao YU , Yong Guo ZHOU , Pei Guo LI
2005, 16(7): 991-994
[Abstract](187) [FullText HTML] [PDF 1443KB](6)
Chitosan membrane was modified by the selective oxidization of chitosan molecules on its surface with NO2 gas. FTIR spectra indicated there were plenty of-COOH and-COO- groups on the modified membrane surface. The SEM study showed the modified membrane surface was rough rather than smooth as chitosan membrane. All antithrombosis test, hemolysis test and blood cell morphology observation with SEM revealed that modified chitosan membranes have superior blood compatibility to chitosan.
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