引用本文:
Ai Ye LIANG, Yu Guang DU, Ke Yi WANG, Bing Cheng LIN. Capillary Zone Electrophoresis Investigation of Interactions between Granulocyte-colony Stimulating Factor and Dextran Sulfate/Carrageenan Oligosaccharide[J]. Chinese Chemical Letters,
2005, 16(5): 647-650.
Citation: Ai Ye LIANG, Yu Guang DU, Ke Yi WANG, Bing Cheng LIN. Capillary Zone Electrophoresis Investigation of Interactions between Granulocyte-colony Stimulating Factor and Dextran Sulfate/Carrageenan Oligosaccharide[J]. Chinese Chemical Letters, 2005, 16(5): 647-650.

Citation: Ai Ye LIANG, Yu Guang DU, Ke Yi WANG, Bing Cheng LIN. Capillary Zone Electrophoresis Investigation of Interactions between Granulocyte-colony Stimulating Factor and Dextran Sulfate/Carrageenan Oligosaccharide[J]. Chinese Chemical Letters, 2005, 16(5): 647-650.

Capillary Zone Electrophoresis Investigation of Interactions between Granulocyte-colony Stimulating Factor and Dextran Sulfate/Carrageenan Oligosaccharide
摘要:
The interactions between granulocyte-colony stimulating factor (G-CSF) and dextran sulfate/κ-carrageenan oligosa1ccharide were studied by capillary zone electrophoresis. Dextran sulfate could strongly interact with G-CSF and the complex was detected. The binding constant and stoichiometry were determined to be 1.2×106 (mol/L)-1 and 3:1, respectively. However, the interaction between κ-carrageenan oligosaccharide and G-CSF was not found.
English
Capillary Zone Electrophoresis Investigation of Interactions between Granulocyte-colony Stimulating Factor and Dextran Sulfate/Carrageenan Oligosaccharide
Abstract:
The interactions between granulocyte-colony stimulating factor (G-CSF) and dextran sulfate/κ-carrageenan oligosa1ccharide were studied by capillary zone electrophoresis. Dextran sulfate could strongly interact with G-CSF and the complex was detected. The binding constant and stoichiometry were determined to be 1.2×106 (mol/L)-1 and 3:1, respectively. However, the interaction between κ-carrageenan oligosaccharide and G-CSF was not found.

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