β-Lactam Templated Macrocyclization:Synthesis of 12-Membered Macrolide

Guo Juan LIANG Jin Zhong ZHANG An Qi CHEN

引用本文: Guo Juan LIANG,  Jin Zhong ZHANG,  An Qi CHEN. β-Lactam Templated Macrocyclization:Synthesis of 12-Membered Macrolide[J]. Chinese Chemical Letters, 2005, 16(5): 601-603. shu
Citation:  Guo Juan LIANG,  Jin Zhong ZHANG,  An Qi CHEN. β-Lactam Templated Macrocyclization:Synthesis of 12-Membered Macrolide[J]. Chinese Chemical Letters, 2005, 16(5): 601-603. shu

β-Lactam Templated Macrocyclization:Synthesis of 12-Membered Macrolide

  • 基金项目:

    This work is supported by the National Natural Science Foundation of China (grant No:20372056) and a Research Fund from the Royal Society of Chemistry, UK.

摘要: A novel macrolactonization method was developed using a chiral β-lactam as the template. This novel method features that the macrocyclization is simultaneously achieved while a TBS protected hydroxy group is deprotected.

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  • 收稿日期:  2004-05-09
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