Cleavage of DNA by a New Mixed-ligand Cu(Ⅱ) Complex

Qing Hua ZHOU Pin YANG

引用本文: Qing Hua ZHOU,  Pin YANG. Cleavage of DNA by a New Mixed-ligand Cu(Ⅱ) Complex[J]. Chinese Chemical Letters, 2005, 16(1): 81-84. shu
Citation:  Qing Hua ZHOU,  Pin YANG. Cleavage of DNA by a New Mixed-ligand Cu(Ⅱ) Complex[J]. Chinese Chemical Letters, 2005, 16(1): 81-84. shu

Cleavage of DNA by a New Mixed-ligand Cu(Ⅱ) Complex

  • 基金项目:

    The authors acknowledge the support of the National Natural Science Foundation of China (No:20171031) and the Shanxi Provincial Natural Science Foundation for Youth (No:20011007).

摘要: Cleavage of DNA pUC19 by [Cu (saldien) (NH3)]Cl2 (here, saldien=bis (salicylicdene)-diethylenetriamine) was investigated at different pHs, times, concentrations, and 37℃. It was found that the copper (Ⅱ) complex could cleave DNA without added coreactants.

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  • 收稿日期:  2003-10-31
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