Synthesis of 2-En-1-one-ebelactonyl Benzoates of Territrem B Analogues from Jujubogenin

• Jin Hao ZHAO ^1,2, ,
• Yan Guang WANG ^2, ,
• Hai Bo LI ^1, ,
• Feng ZHAO ^1, ,
• Lei Xiang YANG ^1, ,
• Hua BAI ^3, ,
• Shoei Sheng LEE ^4, ,
• Yu ZHAO ^1,

• 1.

  Department of Traditional Chinese Medicine and Natural Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031;

• 2.

  Department of Chemistry, College of Sciences, Zhejiang University, Hangzhou 310027;

• 3.

  Zhejiang Hisun Naturelite Pharmaceutical R & D Co., Ltd., Hangzhou 310007;

• 4.

  Department of Pharmacy, College of Medicine, National Taiwan University, Taipei 10018

• Received Date: 18 November 2003
  
• Fund Project:

  ritte and Dr. O. Baudoin (CNRS) for useful discussions. We are grateful to Dr. Xiaojiang Hao (KIB, CAS) for helpful suggestions. One of the authors (Y. Zhao) would also like to express his thanks to the Chinese Ministry of Education as well as to Mr. Ka-shing Li for the"Cheung Kong Scholars Chair Professorship" at Zhejiang University.

  The authors would like to thank Dr. F. Gué