Studies on a New Usage of Hypophosphorous Acid-iodine System in N-C Bond Cleavage

Ge MENG Ling ZHAO You Fu LUO Fen Er CHEN

引用本文: Ge MENG,  Ling ZHAO,  You Fu LUO,  Fen Er CHEN. Studies on a New Usage of Hypophosphorous Acid-iodine System in N-C Bond Cleavage[J]. Chinese Chemical Letters, 2003, 14(4): 351-354. shu
Citation:  Ge MENG,  Ling ZHAO,  You Fu LUO,  Fen Er CHEN. Studies on a New Usage of Hypophosphorous Acid-iodine System in N-C Bond Cleavage[J]. Chinese Chemical Letters, 2003, 14(4): 351-354. shu

Studies on a New Usage of Hypophosphorous Acid-iodine System in N-C Bond Cleavage

摘要: A mixture of hypophosphorous acid (H3PO2) and iodine in acetic acid can cleave the N-alkyl bond in a variety of N-1 substituted pyrimidine derivative in relatively high yields, withoutany damage to the amido bond in the non-nucleosides pyrimidine base skeleton.

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  • 收稿日期:  2002-05-27
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