Synthesis of Novel Nucleoside:2'-deoxyuridine-3',5'-di(4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybipheny1-2-methoxy carbonyl 2'-carboxylate)

Rui Yun GUO Jun Biao CHANG Rong Feng CHEN Jing Xi XIE

引用本文: Rui Yun GUO,  Jun Biao CHANG,  Rong Feng CHEN,  Jing Xi XIE. Synthesis of Novel Nucleoside:2'-deoxyuridine-3',5'-di(4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybipheny1-2-methoxy carbonyl 2'-carboxylate)[J]. Chinese Chemical Letters, 1999, 10(5): 341-344. shu
Citation:  Rui Yun GUO,  Jun Biao CHANG,  Rong Feng CHEN,  Jing Xi XIE. Synthesis of Novel Nucleoside:2'-deoxyuridine-3',5'-di(4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybipheny1-2-methoxy carbonyl 2'-carboxylate)[J]. Chinese Chemical Letters, 1999, 10(5): 341-344. shu

Synthesis of Novel Nucleoside:2'-deoxyuridine-3',5'-di(4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybipheny1-2-methoxy carbonyl 2'-carboxylate)

摘要: Abstract:Hepatitis B Virus (HBV) belongs to the family of hepadnaviridae which comprises several animal viruses, including human HBV, woodchuck hepatitis (WHV), ground squirrel hepatitis virus (GSHV) and duck hepatitis B virus (DHBV). These viruses share common features such as the genome organization, mode of replication and similar tropism for hepatocytes1. 2'-deoxyuridine-substituted biphenyl carboxylate was synthesized as anti-hepatitis B agents. The structure was confirmed by UV, 1HNMR spectrum and elementary analysis.

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  • 收稿日期:  1998-09-14
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