引用本文:
Chen MA, Tong Hut ZHOU. Studies on Different Hydrolysis Procedures for Drugs of Abuse in Hair[J]. Chinese Chemical Letters,
1999, 10(3): 239-242.
Citation: Chen MA, Tong Hut ZHOU. Studies on Different Hydrolysis Procedures for Drugs of Abuse in Hair[J]. Chinese Chemical Letters, 1999, 10(3): 239-242.
Citation: Chen MA, Tong Hut ZHOU. Studies on Different Hydrolysis Procedures for Drugs of Abuse in Hair[J]. Chinese Chemical Letters, 1999, 10(3): 239-242.
Studies on Different Hydrolysis Procedures for Drugs of Abuse in Hair
摘要:
Different hydrolysis and extraction procedures have been studied for the determination of drugs of abuse in hair samples.The results showed that acid and enzymatic hydrolysis gave high extraction recoveries for 6-monoacetylmorphine.morphine.codeine and heroin.Enzymatic hydrolysis was more expensive.After alkaline hydrolysis.6-monoacetylmorphine.a unique proof of heroin abuse.could not be detected and after methanolic extraction.the extract was dirty and the obtained chromatogram showed an interfering background.It is concluded that acid hydrolysis is the extraction method of choice.
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关键词:
- Drugs of abuse
- / hydrolysis
- / hair
English
Studies on Different Hydrolysis Procedures for Drugs of Abuse in Hair
Abstract:
Different hydrolysis and extraction procedures have been studied for the determination of drugs of abuse in hair samples.The results showed that acid and enzymatic hydrolysis gave high extraction recoveries for 6-monoacetylmorphine.morphine.codeine and heroin.Enzymatic hydrolysis was more expensive.After alkaline hydrolysis.6-monoacetylmorphine.a unique proof of heroin abuse.could not be detected and after methanolic extraction.the extract was dirty and the obtained chromatogram showed an interfering background.It is concluded that acid hydrolysis is the extraction method of choice.
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Key words:
- Drugs of abuse
- / hydrolysis
- / hair
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