Synthesis of the (3R, 9S, 10S)-Diastereoisomer of Panaxytriol,a Potent Antitumor Polyacetylene from Panax ginseng

Wei LU Guang Rong ZHENG Jing Shan SHEN Jun Chao CAI

引用本文: Wei LU,  Guang Rong ZHENG,  Jing Shan SHEN,  Jun Chao CAI. Synthesis of the (3R, 9S, 10S)-Diastereoisomer of Panaxytriol,a Potent Antitumor Polyacetylene from Panax ginseng[J]. Chinese Chemical Letters, 1999, 10(3): 201-204. shu
Citation:  Wei LU,  Guang Rong ZHENG,  Jing Shan SHEN,  Jun Chao CAI. Synthesis of the (3R, 9S, 10S)-Diastereoisomer of Panaxytriol,a Potent Antitumor Polyacetylene from Panax ginseng[J]. Chinese Chemical Letters, 1999, 10(3): 201-204. shu

Synthesis of the (3R, 9S, 10S)-Diastereoisomer of Panaxytriol,a Potent Antitumor Polyacetylene from Panax ginseng

  • 基金项目:

    We thank the State Key Laboratory of Drug Research for financial support.

摘要: (3R, 9S.lOS)-Heptadec-l-ene-4,6-diyne-3.9.10-triol 2.a diastereoisomer of panaxytriol 1 was synthesized using L-(+)-diethyl tartrate 5 as a chiral template.through the Cadiot-Chodkiczwicz coupling of the terminal acetylene 3 with bromoacetylene 4.

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  • 收稿日期:  1998-08-31
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