A Theoretical Research on the Intermediate in the Reaction of N-Phosphorylamino-acid to form Peptide or Ribotide

Ru Gang ZHONG Zhao Long LI Yu Fen ZHAO Qian Huan DAI

引用本文: Ru Gang ZHONG,  Zhao Long LI,  Yu Fen ZHAO,  Qian Huan DAI. A Theoretical Research on the Intermediate in the Reaction of N-Phosphorylamino-acid to form Peptide or Ribotide[J]. Chinese Chemical Letters, 1998, 9(11): 1005-1006. shu
Citation:  Ru Gang ZHONG,  Zhao Long LI,  Yu Fen ZHAO,  Qian Huan DAI. A Theoretical Research on the Intermediate in the Reaction of N-Phosphorylamino-acid to form Peptide or Ribotide[J]. Chinese Chemical Letters, 1998, 9(11): 1005-1006. shu

A Theoretical Research on the Intermediate in the Reaction of N-Phosphorylamino-acid to form Peptide or Ribotide

  • 基金项目:

    This work was supported by the National Education Committee of China and the National Natural Science Foundation of China (Grant No. 29632004)

摘要: In order to explain the high activity of N-phosphoryl-α-amino acids, ab initio and MNDO calculations are performed to study the reaction pathway of the intermediate formation from N-dimethylphosphoryl-a-alanine (DMP-α-Ala) and the structures and energies involved in the reaction.

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  • 收稿日期:  1998-02-27
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