1995 Volume 6 Issue 10

A NOVEL REDUCTIVE TETRAALLYLATION OF PYRIDINE
Xian Mou ZENG , Jia Qiang CAI , Yi Jian GU
1995, 6(10): 833-834
[Abstract](161) [FullText HTML] [PDF 92KB](0)
Abstract:
Pyridine and 4-picoline undergo reductive tetraallylation with allyl bromide and zinc dust in THF at room temperature to afford regio-selectively 1,2,3,6-tetraallyl-1,2,3,6-tetrahydropyridine and 1,2,3,6-tetraallyl-1,2,3,6-tetrahydro-4-picoline, respectively.
STUDY ON THE REARRANGEMENT REACTION OF 5-AMINO-1-AMINOCARBONYL-1,2,AND ITS ANALOGUES
Rong Jian LU , Hua Zheng YANG , Bao Ying QIAN , Hai Yan DENG
1995, 6(10): 835-838
[Abstract](167) [FullText HTML] [PDF 107KB](1)
Abstract:
The discovery of a rearrangement reaction of 5-amino-1-arylaminocarbcnyl-1,2,4-triazole (pyrazole) to 5-arylureylene-1,2,4-trazole and the mechanism for this rearrangement reaction are presented.The rearrangement reaction could be attributed to a thermodynamic energy preference leading to the predominant formation of 5-arylureylene-1,2,4-triazole,as shown by molecular mechanics calculation with MMX program.
CYCLOTRIMERIZATION OF NITRILES BY THE REACTIVE ALKALI METAL HYDRIDES
Wen Ming ZHANG , Li ZHANG , Shi Jian LIAO , Yun XU , Dao Rong YU
1995, 6(10): 839-842
[Abstract](161) [FullText HTML] [PDF 139KB](0)
Abstract:
In the presence of reactive alkali metal hydrides,nitriles can be cyclotrimerized to give 2,4,6-trisubstituted-1,3,5-triazines and 2,4,6-trisubstituted imidazoles in moderate yield.
STUDIES ON THE SYNTHESIS OF SESAMIN-GROUP LIGNANS* V. A CONVENIENT METHOD FOR THE PREPARATION OF 2-ARYL-4-PHENYLOXAZOLES
Bing Zi CHEN , Jian PEI , Jie WU , Xiu Lin YE
1995, 6(10): 843-846
[Abstract](177) [FullText HTML] [PDF 150KB](1)
Abstract:
Nine 2-aryl-4-phenyloxazoles are prepared from phenacyl benzoates and acetamide in boiling xylene under the action of boron fluoride as catalyst.By this improved method the oxazoles are obtained as single products with yields ranging 75-90%.
SYNTHESIS AND POTENTIAL ANTINEOPLASTIC ACTIVITY OF α-(1-CYCLOPENTENYL) CYCLOPENTANONE DERIVATIVES-A NEW FAMILY OF ANTICANCER AGENTS
Chuan Min QI , Zhi Zhong JI
1995, 6(10): 847-850
[Abstract](151) [FullText HTML] [PDF 156KB](0)
Abstract:
In search for anticancer agents,thirteen new α,β-unsaturated and β-aminomethyl cyclopentanones containing α-(1-cyclopentenyl) have been synthesized by condensation and by Mannich reaction respectively.Anticancer test showed that all title compounds have significant activities against P385,Hela.HepA and EAC in vitro.Part of these compounds were shown to have activity against EAC tumour in vivo.
SYNTHESIS OF FUSED PHOSPHORUS HETEROCYCLIC COMPOUNDS(Ⅱ)
Hua Zheng YANG , Rong Jian LU , Zhen Feng SHANG
1995, 6(10): 851-852
[Abstract](170) [FullText HTML] [PDF 79KB](0)
Abstract:
Using cation exchange resin (D72,Amberlyst-15) as catalyst,Mannich-type reaction of 5-amino-1,2,4-triazole 1,containing guanidine substructure,provides an efficient synthesis of a new kind of bicyclic P-and N-containing compounds,6-phospha-4,5,6-trihydroimidazolo [2,3-e] 1,2,4-triazofe 4.
STUDIES ON THE PRENYLFLAVOIDS PART X Ⅵ SYNTHESIS OF (±)-3',4'-METHYLENEDIOXYISODERICINE-A AND (±)-PONGAPINONE-B
Xian Yong BU , Lian Yun ZHAO , Yu Lin LI
1995, 6(10): 853-854
[Abstract](156) [FullText HTML] [PDF 81KB](0)
Abstract:
3',4'-Methylenedioxyisodericine-A and pongapinone-B were first synthesized via the condensation of piperonal with 2-hydroxy-4-methoxy-3-prenylacetophenone and 4,6-dimethoxy-2-hydroxy-3-prenylacetophenone respectively followed by cyclization.
STUDY ON NEW PHOSPHORUS-GERMANIUM COMPOUNDS
Ru Yu CHEN , Lun Zu LIU , Zhong Biao ZHANG
1995, 6(10): 855-856
[Abstract](161) [FullText HTML] [PDF 61KB](0)
Abstract:
The spirobicyclic pentacoordinated germanium compounds are synthesized by one pot reaction of diethyl N,N-bis-(2-hydroxyethyl) aminomethyl phosphonate with tetraethoxygermane and Z(OH)2(Z=CH2CH2,CH(CH3)CH2,CH(CH3)CH(CH3),1,2-C6H4).The products were confirmed by 1HNMR,31PNMR and MS spectra.
A FACILE SYNTHESIS OF CHIRAL 3-ALKYL-3,4-DIHYDRO-2H-1,4-BENZOXAZINE DERIVATIVES
Lun Jia XIE
1995, 6(10): 857-860
[Abstract](166) [FullText HTML] [PDF 148KB](0)
Abstract:
This paper describes a facile synthesis of chiral 3-alkyl-3,4-dihydro-2H-1,4-benzoxazine derivatives 1,in which (S) or (R) configuration (1b or 1c)is obtainable.
SYNTHESIS OF PHOSPHONO-DIPEPTIDES BY MANNICH-TYPE AND ARBUZOV-TYPE REACTIONS
Ru Yu CHEN , Qing DAI
1995, 6(10): 861-862
[Abstract](157) [FullText HTML] [PDF 63KB](0)
Abstract:
Two kinds of phosphono-dipeptides have been synthesized by the Mannich-type or Arbuzov-type reaction.The structures of new products have been confirmed by 1H NMR,31P NMR,IR,MS and elemental analyses.
AN EFFICIENT AND STEREOSPECIFIC SYNTHESIS OF 1-PALMITOYL-2-[(z,z,z)-9,12,15-LINOLENOYL]-SN 2-GLYCEROPHOSPHOCHOLINE
Jie XIA , Yong Zheng HUI
1995, 6(10): 863-866
[Abstract](174) [FullText HTML] [PDF 170KB](0)
Abstract:
A polyunsaturated mixed-acid phosphatidylcholine, 1-palmitoyl-2-linoienoyl-sn-glycerophosphocholine (1) prepared from D-mannitol as an optically active starting material is described.
INVESTIGATION ON THE INTERACTION OF THE HALOGEN ATOMS WITH THE C60 CAGE IN THE HALOGEN-ENCLOSED COMPLEXES (HALOGEN@C60)
Chuan Bao ZHU , Ji Min YAN
1995, 6(10): 867-870
[Abstract](164) [FullText HTML] [PDF 173KB](0)
Abstract:
The interaction between C60 cage and the center halogen atoms in endohedral complexes (Halogen@C60) (Halogen=Hal=F,Cl,Br,I),including electro-static interaction,dispersive interaction and repulsive interaction,have been calculated by molecular mechanics method combined with the results obtained by quantum-chemical EHMO/ASED method.The computational results show that the total interaction is attraction which reduces the energy of the endohedral complex system except for (I@C60),and the electro-static interaction plays a decisive role in the three forms of interactions,reaching up more than 90%.For the endohedral complex (I@C60),the resultant non-bonded interaction is repulsive.There is a similar variation trend for the total energy variation of system △Etot and the total interaction energy Einter,of which the order is (F@C60) < (Cl@C60) < (Br@C60) < (I@C60).
A NEW APPLICATION OF HYDRIZIRCONOCENE CHLORIDE,CROSS COUPLING OF ALKENYL STANNANE WITH ALLYL BROMIDE
Ji Tao WANG , Yu Ming XU , Hai Jun HAO
1995, 6(10): 871-872
[Abstract](166) [FullText HTML] [PDF 73KB](0)
Abstract:
Alkenyl stannane after hydrozirconation,coupled with allyl bromide using CuCN as catalyst producing allyl homologated stannane.
O-METHYLLAUREOLOL FROM SKIMMIA LAUREOLA
Hong Jie ZHANG , Xin Feng GAO , Ming Zhe ZHANG
1995, 6(10): 873-874
[Abstract](170) [FullText HTML] [PDF 74KB](0)
Abstract:
A new triterpene alcohol was isolated and identifed by specrtral analyses from Skimmia laureola ssp.multinervia which was collected from Yunnan province of China and named O-methyllaureolol.
NEW SESQUITERPENE FROM LIGULARIA SAGITTA
Li YANG , Hai Ruo PENG , Zhong Jiang JIA
1995, 6(10): 875-876
[Abstract](167) [FullText HTML] [PDF 82KB](2)
Abstract:
A new eremophilane acid was isolated in the phytochemical investigation of the roots of Ligularia sagitta.Its structure and stereochemistry were elucidated by 1D NMR and 2D NMR techniques including 1H-1H COSY,13C-1H COSY,13C-1H COLOC and NOESY.
QUINOLONE ALKALOIDS FROM EVODIA RUTAECARPA BENTHAM
Yuan Qing TANG , Xiao Zhang FENG , Liang HUANG
1995, 6(10): 877-878
[Abstract](154) [FullText HTML] [PDF 106KB](0)
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A new quinolone alkaloid was isolated from the fruit of Evodia rutaecarpa Bentham (Rutaceae) with three known alkaloids,and their structures were determined on the basis of spectral data and chemical transformations.
FLUORESCENCE SPECTROSCOPY STUDIES ON TIIE ACTION OK RARE EARTHS WITH BOVINE SERUM ALBUMIN IN MULTIMOLECULAR SYSTEM
ZHi Qiang WANG , Gong ZHANG , Qi Min LIU , Jia Zan NI
1995, 6(10): 879-882
[Abstract](154) [FullText HTML] [PDF 155KB](0)
Abstract:
In this paper,the interaction of tripositive terbium ions (Tb3+) with bovine serum albumin (DSA) has been investigated in the presence of some alkaline earth metals and citric acid (Cit) by using fluorescence spectroscopy.The results show that Tb3+,BSA and Cit can form ternary complex BSA·Tb2·Cit4 in μ=0.1mol/1 NaCl,pH 6.3 hexaniethylenetetramine buffer.Other rare earths are able to compete for the same binding site in BSA with Tb3+.The sequence of competition is Eu3+ > Pr3+ > Yb3+ > Gd3+ > La3+.Ca2+ and Mg2+ can not replace Tb bound to BSA.
RUTHENTUM (Ⅱ) COORDINATION COMPOUNDS WITH POLYPYRIDINE (Ⅲ):STEREOSELECTIVITY OF TRIS (PHENANTHROLINE) RUTHENIUM BINDING IN DNA
Lei WANG , Guang YANG , Jian Zhong WU , Tian Xian ZENG , Liang Nian JI , Xuan TIAN
1995, 6(10): 883-884
[Abstract](164) [FullText HTML] [PDF 108KB](0)
Abstract:
The binding of coordination compound Ru(phen)32+ to calf thymus DMA and herring sperm DNA has been investigated by absorption,emission and circular dichroism spectroscopy. Measurement of enantioselectivily combined with photophysical experiment shows the binding of Ru(phen)32+ with calf thymus DNA is of intercalatively bound mode,but the binding of Ru(phen)32+ with herring sperm DNA is of surface-bound mode.
STUDIES ON THE ANIONIC SPECIES OF SODIUM ALUMINATE SOLUTIONS OF LOW CAUSTIC RATIOS
Yi Lin CAO , Hong Lin LIU , Nian Yi CHEN
1995, 6(10): 885-886
[Abstract](168) [FullText HTML] [PDF 92KB](0)
Abstract:
UV and Raman spectra were used in the studies of anionic species in sodium aluminate solutions.Two absorption peaks near 233nm and 270nm in UV spectra were found and assigned to Al(OH)4 and [(HO)3Al-O-Al(OH)3]2- respectively,while the results of Raman spectra measurements and quantum chemical calculations by using MNDO and DV-Xα methods were in good agreement with the above conclusions.
ASSIGNMENTS FOR THE GROUND STATES OF METAL MONOCARBONYLS
Xin XU , Nan Qin WANG , Xin LV , Qian Er ZHANG
1995, 6(10): 887-890
[Abstract](161) [FullText HTML] [PDF 181KB](0)
Abstract:
The bonding mechanisms between the first-row transition metal and carbon monoxide were discussed.Three basic rules have been drawn up to determine the ground states of the metal monocarbonyls.The theoretical assignments are in full agreement with the existing experimental results.
AROYL HYDRAZONES CONTAINING TRIAZOLE AND THEIR BIVALENT METAL COMPLEXES
Ding Bo WANG , Yong Min LIANG , Yong Xiang MA
1995, 6(10): 891-892
[Abstract](170) [FullText HTML] [PDF 88KB](0)
Abstract:
Two new ligands.aroyl hydrazones containing triazole and some of their bivalent transition metal complexes have been synthesized.The complexes were characterized by elemental analyses,IR,UV,XPS and thermal analyses.Two ligands were characterized by NMR spectra also.
RUTHENIUM COORDINATION COMPOUBNDS WITH POLYPYRIDINES Ⅳ. SYNTHESIS AND CHARACTERIZATION OF (2-PHENYL)IMIDAZO[f] 1,10-PHENANTHROLINE AND THEIR Ru(Ⅱ) COORDINATION COMPOUNDS
Jian Zhong WU , Lei WANG , Guang YANG , Tian Xian ZENG , Lisng Nian JI
1995, 6(10): 893-896
[Abstract](158) [FullText HTML] [PDF 144KB](0)
Abstract:
Two new polypyridine liganda,imidazo[f]1,10-phenanthroline (IP) and 2-phenyl-imidazo[f]1,10-phenanthroline (PIP) and their Ru(Ⅱ) mixed type coordination compounds together with 2,2'-bipyridine (bpy) and 1,10-phenanthroline(phen) are synthesized and characterized by elemental analyses,melting points,electronic absorption,IR,emission spectra and cyclic voltammetry.
SYNTHESIS,STRUCTURE AND THERMOREANGEMENT OF TRTRA METHYLDISILANDIYL BIS(1-INDENYL) TETRACARBONYL DI-IRON
Xiu Zhong ZHOU , Bai Quan WANG , Shan Sheng XU
1995, 6(10): 897-898
[Abstract](205) [FullText HTML] [PDF 77KB](0)
Abstract:
The title compound (Me2SiSiMe2)[η5-1-indenyl)Fe(CO)]2(μ-CO)2(1) was prepared by the reaction of 1.2-bis(1-indenyl)tetramethyldisilane and Fe(CO)5 in relluxing heptane.1 in refluxing xylene can be converted into [Me2Si(η5-1-indenyl) Fe(CO)2]2(2).The pure trans isomer 2t was obtained and its crystal and molecular structure was determined by X-ray diffraction.
CRYSTAL STRUCTURE OF (Et4N)2Pd(i-MNT)2 AND ITS REACTION WITH (Et4N)2WS4 (i-MNT=S2CC(CN)22-)
De Liang LONG , Xin Quan XIN , Bao Sheng LUO , Liao Rong CHEN , Kai Bei YU
1995, 6(10): 899-902
[Abstract](181) [FullText HTML] [PDF 117KB](1)
Abstract:
(Et4N)2Pd(i-mnt)2,fw=647.04,monociinic,space group P21/c;a=9.511(1),b=11.612(2),c=14.820(3)Å,β=94.38(1)°, V=1631.9(5)Å3, Z=2, Dc=1.32 g·cm-3, F(000)=672, R=0.0324, RW=0.0298. This is a new example of X-ray characterized Pd complexes with bivalent anion 1,1-dithiolato ligands and its reaction with(Et4N)2WS4 gives (Et4N)2WS4Pd(i-mnt).
LANGMUIR-BLODGETT FILM OF STRONG LUMINESCENT EUROPIUM DIBENZOYLMETHANE COMPLEXES
De Jian ZHOU , Guang QinG YAO , Chun Hui HUANG , Jie BAI , Tian Kai LI
1995, 6(10): 903-906
[Abstract](162) [FullText HTML] [PDF 183KB](0)
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Two strong fluorescent amphiphilic europium-dibenzoylmethane complex:Me3NC16H33.Fu(DBM)4.(A) and Et3NC18H37.Eu(DBM)4 (B) have been synthesized and their Langmuir films have been formed at the air/water interface.The Langmuir film of A can be easily transferred onto hydrophilic substrates with transfer ratio around unity to build up Langmuir-Blodgett (LB) films.The LB films were characterized by UV-vis spectra and low-angle X-ray diffraction.Their fluorescence spectra and fluorescence lifetime have been studied both in solution and highly ordered LB films.
SYNTHESIS AND PRELIMINARY CHARACTERIZATION OF NORBORNENE-ETHYLENE BLOCK COPOLYMER
Qing WU , Ze Jian LU , Fang Cheng TANG
1995, 6(10): 907-910
[Abstract](168) [FullText HTML] [PDF 119KB](0)
Abstract:
Transformation of living ring-opening metathesis polymerization (ROMP) into coordination polymerization by converting the titanacyclobutane attached to a polynorbornene (polyNBE) chain into titanocene alkoxide has been used to the synthesis of poly(NBE-b-ethylene).The copolymerization product,after being extracted by CH2Cl2 to separate the NBE homopolymer,exhibits the Tg of polyNBE segments and Tm of polyethylene segments by DSC measurement.
A NOVEL METHOD OF SECONDARY SYNTHESIS OF FeY ZEOLITE
Ai Min ZHANG , Shu Lin BAO , Qin Hua XU
1995, 6(10): 911-914
[Abstract](166) [FullText HTML] [PDF 174KB](0)
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FeY zeolites were prepared by three different secondary synthetic methods.Samples were characterized with XRD,IR,ESR,MBS and XPS techniques.The results showed that more iron ions were inserted into the framework of zeolite when the sample was pretreated with (NH4)2SiF6 aqueous sotution.The structure of such zeolites has obviously changed due to the iron ions inserted into the framework.
PREPARATION OF SPHERICAL,MONODISPERSED NANOMETER Eu2O3 PARTICLES
Jun MA , Qi Jie YAN
1995, 6(10): 915-918
[Abstract](179) [FullText HTML] [PDF 143KB](0)
Abstract:
Spherical,monodispersed europium hydroxycarbonate particles were obtained by homogeneous precipitation with urea in aqueous solution of Eu(NO3)3 at elevated temperature.The particles were readily converted to the uniform EU2O3 with average particle size of 50nm after calcined at 750℃.
ENDOTOXIN REMOVAL BY MEMBRANE AFFINITY CHROMATOGRAPHY
Wei GUO , Zhen Hua SHANG , Yi Nian YU , Liang Mo ZHOU , Zhong Yi SUN , Li Ren MA , Mei Yun CHEN
1995, 6(10): 919-922
[Abstract](145) [FullText HTML] [PDF 207KB](0)
Abstract:
Endotoxin was removed by membrane affinity chromatography.Macropore cellulose membrane was prepared from filter paper by alkaline treatment and chemical crosslinking,and was used as stationary phase for affinity chromatography.The matrix membrane was derived by hexamethylenediamine and activated by glutaraldehyde before histidine was immobilized as affinity ligand.A membrane cartridge containing 40 sheets of affinity membrane was also prepared,which can be used to remove pyrogen from aqueous solutions.
STUDIES ON LOW MOLECULAR WEIGHT MATERIALS CONTAINED IN POLY(P-PHENYLENE SULFIDE)
Mei Ming LUO , Can Shu HOU , Jie YANG , Yong Rong CHEN , Qi Xian WU
1995, 6(10): 923-926
[Abstract](153) [FullText HTML] [PDF 154KB](0)
Abstract:
Low molecular weight materials contained in PPS resin were obtained by extracting PPS powder exhaustively with xylene and examined by solid probe mass spectroscopy.Six families of oligomers have been identified in the extract.Cyclopenta (p-phenylene sulfide) (Ⅰ) and cyclohexa (p-phenylene sulfide) (Ⅱ) have been isolated from PPS by extraction and recrystallization,and characterized.
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