SYNTHESIS OF ANALOGUES OF HUPERZINE A 2. The Preparation of Some Analogues with Huperzine A Skeleton

Xu Chang HE Zhen Rong XU Yun Long LI Zhao Ying WANG Dong Lu BAI

引用本文: Xu Chang HE,  Zhen Rong XU,  Yun Long LI,  Zhao Ying WANG,  Dong Lu BAI. SYNTHESIS OF ANALOGUES OF HUPERZINE A 2. The Preparation of Some Analogues with Huperzine A Skeleton[J]. Chinese Chemical Letters, 1994, 5(6): 471-474. shu
Citation:  Xu Chang HE,  Zhen Rong XU,  Yun Long LI,  Zhao Ying WANG,  Dong Lu BAI. SYNTHESIS OF ANALOGUES OF HUPERZINE A 2. The Preparation of Some Analogues with Huperzine A Skeleton[J]. Chinese Chemical Letters, 1994, 5(6): 471-474. shu

SYNTHESIS OF ANALOGUES OF HUPERZINE A 2. The Preparation of Some Analogues with Huperzine A Skeleton

摘要: Huperzine A (1),a new Lycopodium alkaloid isolated from Chinese traditional medicine Huperzia Serrata,is a potent acetylcholinesterase inhibitor and a promising drug candidate of treating Alzheimer's disease as well.Several analogues of huperzine A,compound 8,10,14,15 and 17 were prepared and their inhibitory activities of acetylcholinesterase were evaluated.

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  • 收稿日期:  1994-03-09
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