引用本文:
Rui Lian SHAO, Cheng Xin ZHI, You Quan ZHU, Jie You XUE. HIGHLY REGIOSELECTIVE O-AND N-ACYLATION OF 5-METHYL-3-HYDROXYISOXAZOLE[J]. Chinese Chemical Letters,
1992, 3(3): 175-176.
Citation: Rui Lian SHAO, Cheng Xin ZHI, You Quan ZHU, Jie You XUE. HIGHLY REGIOSELECTIVE O-AND N-ACYLATION OF 5-METHYL-3-HYDROXYISOXAZOLE[J]. Chinese Chemical Letters, 1992, 3(3): 175-176.
Citation: Rui Lian SHAO, Cheng Xin ZHI, You Quan ZHU, Jie You XUE. HIGHLY REGIOSELECTIVE O-AND N-ACYLATION OF 5-METHYL-3-HYDROXYISOXAZOLE[J]. Chinese Chemical Letters, 1992, 3(3): 175-176.
HIGHLY REGIOSELECTIVE O-AND N-ACYLATION OF 5-METHYL-3-HYDROXYISOXAZOLE
摘要:
Acylation of 5-methyl-3-hydroxyisoxazole (1) with 3-substituted cyclopropanecarboxylic chlorides (3) in the presence of triethylamine (TEA) in acetonitrile yields predominantly O-acylated products (4).The N-acyl isomers (5) are afforded regiospecifically using trimethylsilyl ether of 3-hydroxyisoxazole (2).
English
HIGHLY REGIOSELECTIVE O-AND N-ACYLATION OF 5-METHYL-3-HYDROXYISOXAZOLE
Abstract:
Acylation of 5-methyl-3-hydroxyisoxazole (1) with 3-substituted cyclopropanecarboxylic chlorides (3) in the presence of triethylamine (TEA) in acetonitrile yields predominantly O-acylated products (4).The N-acyl isomers (5) are afforded regiospecifically using trimethylsilyl ether of 3-hydroxyisoxazole (2).
扫一扫看文章
计量
- PDF下载量: 0
- 文章访问数: 0
- HTML全文浏览量: 0
下载:
