引用本文:
朱晨江, 石焱, 吕遐, 唐燕辉, 陈国荣. 新型碳糖苷类熊果苷类似物的合成及其对酪氨酸酶的抑制活性[J]. 应用化学,
2009, 26(3): 253-256.
Citation: ZHU Chen-Jiang, SHI Yan, LV Xia, TANG Yan-Hui, CHEN Guo-Rong. Synthesis of Novel Arbutin C-glycoside Derivates and Their Inhibition to Tyrosinase[J]. Chinese Journal of Applied Chemistry, 2009, 26(3): 253-256.
Citation: ZHU Chen-Jiang, SHI Yan, LV Xia, TANG Yan-Hui, CHEN Guo-Rong. Synthesis of Novel Arbutin C-glycoside Derivates and Their Inhibition to Tyrosinase[J]. Chinese Journal of Applied Chemistry, 2009, 26(3): 253-256.
新型碳糖苷类熊果苷类似物的合成及其对酪氨酸酶的抑制活性
English
Synthesis of Novel Arbutin C-glycoside Derivates and Their Inhibition to Tyrosinase
Abstract:
A series of stable and effective 4-hydroxyphenyl-D-glucopyranoside derivates were synthesized.The 10 new compounds were characterized by 1H NMR and HRMS.The preliminary test of bioactivity showed that they displayed notable inhibitions to tyrosinase.The inhibitions of compounds 13,14,15,16 and 19 to tyrosinase were equal or better than that of natural arbutin.
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Key words:
- arbutin
- / C-glycoside
- / synthesis
- / inhibitions for tyrosinase
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