引用本文:
卢水明, 陈茹玉. 2,4,6-三氧-1,3,5,2-三氮磷杂环己烷衍生物的合成及其生物活性[J]. 应用化学,
1998, 15(5): 18-20.
Citation: Lu Shuiming, Chen Ruyu. Synthesis and Biological Activity of the Derivatives of 2,4,6-Trioxo-1,3,5,2-triazaphosphorine[J]. Chinese Journal of Applied Chemistry, 1998, 15(5): 18-20.
Citation: Lu Shuiming, Chen Ruyu. Synthesis and Biological Activity of the Derivatives of 2,4,6-Trioxo-1,3,5,2-triazaphosphorine[J]. Chinese Journal of Applied Chemistry, 1998, 15(5): 18-20.
2,4,6-三氧-1,3,5,2-三氮磷杂环己烷衍生物的合成及其生物活性
English
Synthesis and Biological Activity of the Derivatives of 2,4,6-Trioxo-1,3,5,2-triazaphosphorine
Abstract:
A series of the title 2,4,6-trioxo-1,3,5,2-triazaphosphorine derivatives have been synthesized by reaction of N,N-bis(2-chloroethyl)aminophosphoryldiisocyanate with ami nes. The structures of the products were confirmed by 1H NMR, IR MS, 31P NMR and elemental analysis. The preliminary bioassay indicated that some of them had antitumor activity.
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Key words:
- triazaphosphorine
- / synthesis
- / biological activity
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