Synthesis and Antitumor Activity of C-2/C-10 Modified Analogues of Docetaxel

Wei Shuo FANG Hong Yan LIU Qi Cheng

引用本文: Wei Shuo FANG,  Hong Yan LIU,  Qi Cheng. Synthesis and Antitumor Activity of C-2/C-10 Modified Analogues of Docetaxel[J]. Chinese Chemical Letters, 2005, 16(1): 38-40. shu
Citation:  Wei Shuo FANG,  Hong Yan LIU,  Qi Cheng. Synthesis and Antitumor Activity of C-2/C-10 Modified Analogues of Docetaxel[J]. Chinese Chemical Letters, 2005, 16(1): 38-40. shu

Synthesis and Antitumor Activity of C-2/C-10 Modified Analogues of Docetaxel

  • 基金项目:

    Financial support from Funding to Outstanding Doctor Thesis Authors of Chinese Universities (Grant No. 199949) is gratefully acknowledged by W. S. Fang.

摘要: Four 10-propionyl docetaxel analogues (11a-d) with 2α-amido substituents were prepared, and their antitumor activity against three solid tumor cell lines and their drug-resistant counterparts were determined.

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  • 收稿日期:  2003-12-11
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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