Synthesis of 3-Substituted-6-(2,4-Dichlorophenyl)-s-Triazolo[3.4-b]-1,3,4-Oxadiazoles

Xiao Ming FENG Xun HE Yao Zhong JIANG

引用本文: Xiao Ming FENG,  Xun HE,  Yao Zhong JIANG. Synthesis of 3-Substituted-6-(2,4-Dichlorophenyl)-s-Triazolo[3.4-b]-1,3,4-Oxadiazoles[J]. Chinese Chemical Letters, 1997, 8(12): 1021-1024. shu
Citation:  Xiao Ming FENG,  Xun HE,  Yao Zhong JIANG. Synthesis of 3-Substituted-6-(2,4-Dichlorophenyl)-s-Triazolo[3.4-b]-1,3,4-Oxadiazoles[J]. Chinese Chemical Letters, 1997, 8(12): 1021-1024. shu

Synthesis of 3-Substituted-6-(2,4-Dichlorophenyl)-s-Triazolo[3.4-b]-1,3,4-Oxadiazoles

摘要: Fourteen new 2-acylhydrazino-5-(2,4-dichlorophenyl)-1,3,4-oxadiazoles were prepared by nucleophilic displacement of acylhydrazine at the 2-position of 2-methylsulfonyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole.Fourteen new 3-substituted-6-(2,4-dichlorophenyl)-s-triazolo[3,4-b]-1,3,4-oxadiazoles were obtained by treating 2-acylhydrazino-5-(2,4-dichlorophenyl)-1,3,4-oxadiazoles with K2CO3 solution.All the new compounds showed significant antibacterial activity.

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  • 收稿日期:  1997-07-14
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