引用本文:
Miao WANG, Jian Wei YAN, Yan Fei LIN, Jian De LU, Xiao Yun FU. Effect of Micelle Composition on Acidic Drugs Separation Behavior by Micellar Electrokinetic Capillary Chromatography[J]. Chinese Chemical Letters,
2002, 13(12): 1203-1204.
Citation: Miao WANG, Jian Wei YAN, Yan Fei LIN, Jian De LU, Xiao Yun FU. Effect of Micelle Composition on Acidic Drugs Separation Behavior by Micellar Electrokinetic Capillary Chromatography[J]. Chinese Chemical Letters, 2002, 13(12): 1203-1204.
Citation: Miao WANG, Jian Wei YAN, Yan Fei LIN, Jian De LU, Xiao Yun FU. Effect of Micelle Composition on Acidic Drugs Separation Behavior by Micellar Electrokinetic Capillary Chromatography[J]. Chinese Chemical Letters, 2002, 13(12): 1203-1204.
Effect of Micelle Composition on Acidic Drugs Separation Behavior by Micellar Electrokinetic Capillary Chromatography
摘要:
Micellar electrokinetic capillary chromatography (MECC) separation of four acidic drugs similar in structure was studied. Both anionic surfactant sodium dodecyl sulfate (SDS) and nonionic surfactant Tween 20 were used to form single micelles and mixed micelles as pseudostationary phases. The effects of the composition of micellar solution on retention behaviors were studied. The results indicate that there is markedly different selectivity among SDS, Tween 20 and the mixed micelles systems.
English
Effect of Micelle Composition on Acidic Drugs Separation Behavior by Micellar Electrokinetic Capillary Chromatography
Abstract:
Micellar electrokinetic capillary chromatography (MECC) separation of four acidic drugs similar in structure was studied. Both anionic surfactant sodium dodecyl sulfate (SDS) and nonionic surfactant Tween 20 were used to form single micelles and mixed micelles as pseudostationary phases. The effects of the composition of micellar solution on retention behaviors were studied. The results indicate that there is markedly different selectivity among SDS, Tween 20 and the mixed micelles systems.
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Key words:
- Micelle
- / electrokinetic chromatography
- / acidic drug
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