Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines, acridine-l,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-a]quinoline moiety and their antimicrobial activity assess

Niraj K. Ladani ,  Divyesh C. Mungra ,  Manish P. Patel ,  Ranjan G. Patel

引用本文: Niraj K. Ladani,  Divyesh C. Mungra,  Manish P. Patel,  Ranjan G. Patel. Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines, acridine-l,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-a]quinoline moiety and their antimicrobial activity assess[J]. Chinese Chemical Letters, 2011, 22(12): 1407-1410. doi: 10.1016/j.cclet.2011.07.009 shu
Citation:  Niraj K. Ladani,  Divyesh C. Mungra,  Manish P. Patel,  Ranjan G. Patel. Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines, acridine-l,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-a]quinoline moiety and their antimicrobial activity assess[J]. Chinese Chemical Letters, 2011, 22(12): 1407-1410. doi: 10.1016/j.cclet.2011.07.009 shu

Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines, acridine-l,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-a]quinoline moiety and their antimicrobial activity assess

  • 基金项目:

    The authors are grateful to the Department of Chemistry, S P University, India for providing laboratory facilities.

摘要: Microwave assisted efficient Hantzsch reaction via four-component coupling reactions of tetrazolo[l, 5-a]quinoline-4-carbal-dehyde, dimedone/cyclohexane-l, 3-dione, ethyl/methyl acetoacetate and ammonium acetate was described as the preparation of tetrazolo[l, 5-a]quinoline based 1, 4-dihydropyridines, acridine-l, 8-diones and polyhydroquinolines. The process presented here is simple, rapid, environmentally welcoming and high yielding. All the derivatives were subjected to an in vitro antimicrobial screening against a representative panel of bacteria and fungi and results worth further investigations.

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  • 收稿日期:  2011-04-25
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