引用本文:
Zhen Yuan MIAO, Wan Nian ZHANG, Jian Zhong YAO, Chun Quan SHENG, Yun Long SONG, Hui XU, Min ZHANG, Jing ZHANG. Synthesis and Antitumor Activity of 7-Substituted Derivatives of Homocamptothecin[J]. Chinese Chemical Letters,
2006, 17(6): 720-722.
Citation: Zhen Yuan MIAO, Wan Nian ZHANG, Jian Zhong YAO, Chun Quan SHENG, Yun Long SONG, Hui XU, Min ZHANG, Jing ZHANG. Synthesis and Antitumor Activity of 7-Substituted Derivatives of Homocamptothecin[J]. Chinese Chemical Letters, 2006, 17(6): 720-722.
Citation: Zhen Yuan MIAO, Wan Nian ZHANG, Jian Zhong YAO, Chun Quan SHENG, Yun Long SONG, Hui XU, Min ZHANG, Jing ZHANG. Synthesis and Antitumor Activity of 7-Substituted Derivatives of Homocamptothecin[J]. Chinese Chemical Letters, 2006, 17(6): 720-722.
Synthesis and Antitumor Activity of 7-Substituted Derivatives of Homocamptothecin
摘要:
Thirteen homocamptothecin derivatives were synthesized and in vitro antitumor activities were evaluated by the standard MTT method. The results showed that some of the homocamptothecin derivatives had higher antitumor activity than topotecan.
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关键词:
- Antitumor activity
- / homocamptothecin
- / synthesis
English
Synthesis and Antitumor Activity of 7-Substituted Derivatives of Homocamptothecin
Abstract:
Thirteen homocamptothecin derivatives were synthesized and in vitro antitumor activities were evaluated by the standard MTT method. The results showed that some of the homocamptothecin derivatives had higher antitumor activity than topotecan.
-
Key words:
- Antitumor activity
- / homocamptothecin
- / synthesis
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