引用本文:
Xiao Yin YANG, Christian HAUG, Yi Ping YANG, Zhi Sheng HE, Yang YE. Stereoselective Synthesis of syn-and anti-3a-Hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydropyrrolo[2,3-b] indole-2-carboxylic Acid[J]. Chinese Chemical Letters,
2003, 14(2): 130-132.
Citation: Xiao Yin YANG, Christian HAUG, Yi Ping YANG, Zhi Sheng HE, Yang YE. Stereoselective Synthesis of syn-and anti-3a-Hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydropyrrolo[2,3-b] indole-2-carboxylic Acid[J]. Chinese Chemical Letters, 2003, 14(2): 130-132.
Citation: Xiao Yin YANG, Christian HAUG, Yi Ping YANG, Zhi Sheng HE, Yang YE. Stereoselective Synthesis of syn-and anti-3a-Hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydropyrrolo[2,3-b] indole-2-carboxylic Acid[J]. Chinese Chemical Letters, 2003, 14(2): 130-132.
Stereoselective Synthesis of syn-and anti-3a-Hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydropyrrolo[2,3-b] indole-2-carboxylic Acid
摘要:
The structure of syn- and anti-Nb-(p-toluenesulfonyl)-3a-hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydro pyrrolo[2,3-b] indole-2-carboxylic t-butyl ester was stereoselectively synthesized by oxidative ring formation of Nb-(p-toluenesulfonyl)-L-tryptophan t-butyl ester in methylene chloride containing dimethyldioxirane (DMDO), the p-toluenesulfonyl group and t-butyl group can be easily removed by sodium naphthalenide and trifluoroacetic acid, respectively.
English
Stereoselective Synthesis of syn-and anti-3a-Hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydropyrrolo[2,3-b] indole-2-carboxylic Acid
Abstract:
The structure of syn- and anti-Nb-(p-toluenesulfonyl)-3a-hydroxyl-1, 2, 3, 3a, 8, 8a-hexahydro pyrrolo[2,3-b] indole-2-carboxylic t-butyl ester was stereoselectively synthesized by oxidative ring formation of Nb-(p-toluenesulfonyl)-L-tryptophan t-butyl ester in methylene chloride containing dimethyldioxirane (DMDO), the p-toluenesulfonyl group and t-butyl group can be easily removed by sodium naphthalenide and trifluoroacetic acid, respectively.
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