Microwave assisted, ligand free, copper catalyzed reaction of aryl halides with phenyl urea

Sandip N. Gavade Ravi S. Balaskar Madhav S. Mane Pramod N. Pabrekar Murlidhar S. Shingare Dhananjay V. Mane

引用本文: Sandip N. Gavade,  Ravi S. Balaskar,  Madhav S. Mane,  Pramod N. Pabrekar,  Murlidhar S. Shingare,  Dhananjay V. Mane. Microwave assisted, ligand free, copper catalyzed reaction of aryl halides with phenyl urea[J]. Chinese Chemical Letters, 2011, 22(3): 292-295. doi: 10.1016/j.cclet.2010.09.037 shu
Citation:  Sandip N. Gavade,  Ravi S. Balaskar,  Madhav S. Mane,  Pramod N. Pabrekar,  Murlidhar S. Shingare,  Dhananjay V. Mane. Microwave assisted, ligand free, copper catalyzed reaction of aryl halides with phenyl urea[J]. Chinese Chemical Letters, 2011, 22(3): 292-295. doi: 10.1016/j.cclet.2010.09.037 shu

Microwave assisted, ligand free, copper catalyzed reaction of aryl halides with phenyl urea

  • 基金项目:

    Authors are thankful to Head of Department of Chemistry V.G. Vaze College, Mulund (E), Mumbai-81(MS), India for providing the necessary laboratory facilities.

摘要: The ligand free coupling reaction of phenyl urea with different functionalized aryl halides in the presence of air stable Cu2O and t-BuOK as a base gives symmetrical and unsymmetrical diarylureas in relatively high yields. This method is milder than the palladium catalyzed arylation and avoids the use of toxic phosphine ligand.

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  • 收稿日期:  2010-06-17
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