引用本文:
Qiong You WU, Xun ZHU, JIN Qiao WAN, Fan Qi QU, Ling PENG. Synthesis of a Photolabeling Probe for the Study of Antiviral Mechanism of Ribavirin[J]. Chinese Chemical Letters,
2004, 15(8): 907-910.
Citation: Qiong You WU, Xun ZHU, JIN Qiao WAN, Fan Qi QU, Ling PENG. Synthesis of a Photolabeling Probe for the Study of Antiviral Mechanism of Ribavirin[J]. Chinese Chemical Letters, 2004, 15(8): 907-910.
Citation: Qiong You WU, Xun ZHU, JIN Qiao WAN, Fan Qi QU, Ling PENG. Synthesis of a Photolabeling Probe for the Study of Antiviral Mechanism of Ribavirin[J]. Chinese Chemical Letters, 2004, 15(8): 907-910.
Synthesis of a Photolabeling Probe for the Study of Antiviral Mechanism of Ribavirin
摘要:
Ribavirin has been used in urgency to treat SARS patients recently.In order to study its antiviral mechanism by photolabeling approach, we have synthesized and characterized 5-azido-1-(-D-ribofuranosyl-1,2,4-triazole-3-carboxiamide 1 as a photolabeling probe of ribavirin.The azidotriazole nucleoside showed rapid and clean photochemical reaction, suggesting that 1 is a promising probe to study the antiviral mechanism of ribarivin by photolabeling.
English
Synthesis of a Photolabeling Probe for the Study of Antiviral Mechanism of Ribavirin
Abstract:
Ribavirin has been used in urgency to treat SARS patients recently.In order to study its antiviral mechanism by photolabeling approach, we have synthesized and characterized 5-azido-1-(-D-ribofuranosyl-1,2,4-triazole-3-carboxiamide 1 as a photolabeling probe of ribavirin.The azidotriazole nucleoside showed rapid and clean photochemical reaction, suggesting that 1 is a promising probe to study the antiviral mechanism of ribarivin by photolabeling.
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