引用本文:
李万梅. 微通道反应器中连续化合成苯亚甲基丙酮——介绍一个大学化学综合实验[J]. 大学化学,
2019, 34(5): 51-56.
doi:
10.3866/PKU.DXHX201810009
Citation: LI Wanmei. Continuous Synthesis of (E)Benzalacetonein Microchannel Reactor: An Introduction of a Comprehensive Chemical Experiment[J]. University Chemistry, 2019, 34(5): 51-56. doi: 10.3866/PKU.DXHX201810009
Citation: LI Wanmei. Continuous Synthesis of (E)Benzalacetonein Microchannel Reactor: An Introduction of a Comprehensive Chemical Experiment[J]. University Chemistry, 2019, 34(5): 51-56. doi: 10.3866/PKU.DXHX201810009
微通道反应器中连续化合成苯亚甲基丙酮——介绍一个大学化学综合实验
English
Continuous Synthesis of (E)Benzalacetonein Microchannel Reactor: An Introduction of a Comprehensive Chemical Experiment
Abstract:
Micro-reaction is an emerging technology that has been developing rapidly in recent years in all research fields of chemistry. In this experiment, benzaldehyde and acetone were used as the starting materials, thus (E)benzalacetone was continuously synthesized by condensation reaction in the presence of sodium hydroxide. By investigating effects of mole ratio, residence time and reaction temperature, the optimized reaction conditions were determined. The product was characterized by NMR and MS. Compared with traditional batch synthetic methods, the presented method has the advantages of high yield, simple operation, and reproducible experimental results. This work gives advanced technology and ideas in laboratory teaching, which not only enhances students' experimental skills, but also helps students to understand the frontiers of science, research situation, tendency of development and application prospects, as well as inspire students' interest greatly.
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Key words:
- (E)Benzalacetone
- / Microchannel reactor
- / Continuous synthesis
- / Comprehensive experiment
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