The Effect of 19-Substituent on the Stereospecific Hydroxylation of Δ5-Steroids Using Performic Acid as Oxidant

Wei Gang LU Jing Yu SU Long Mei ZENG Hong LI

引用本文: Wei Gang LU,  Jing Yu SU,  Long Mei ZENG,  Hong LI. The Effect of 19-Substituent on the Stereospecific Hydroxylation of Δ5-Steroids Using Performic Acid as Oxidant[J]. Chinese Chemical Letters, 2004, 15(8): 899-902. shu
Citation:  Wei Gang LU,  Jing Yu SU,  Long Mei ZENG,  Hong LI. The Effect of 19-Substituent on the Stereospecific Hydroxylation of Δ5-Steroids Using Performic Acid as Oxidant[J]. Chinese Chemical Letters, 2004, 15(8): 899-902. shu

The Effect of 19-Substituent on the Stereospecific Hydroxylation of Δ5-Steroids Using Performic Acid as Oxidant

  • 基金项目:

    We are grateful to the National Natural Science Foundation of China (Project No.29932030) and Youth teacher foundation of Sun Yat-sen (Zhongshan) University (Project No.1131002) for financial support for this work.

摘要: In the studying of the stereospecific hydroxylation of different Δ5-steroids with performic acid, followed by hydrolysis with CH3OH/KOH, we found 19-substituting groups considerably affected the reaction and we put forward the mechanism.

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  • 收稿日期:  2003-07-09
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